(65 nodes) Glutathione metabolism network (Aspergillus thermomutatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDV56_101487	Uncharacterized protein; Belongs to the GST superfamily. (196 aa)
	CDV56_102290	Aminopeptidase. (885 aa)
	CDV56_100224	GST N-terminal domain-containing protein. (380 aa)
	CDV56_101887	Thioredoxin domain-containing protein. (229 aa)
	CDV56_101275	Uncharacterized protein. (284 aa)
	CDV56_102440	Glutathione synthetase. (517 aa)
	CDV56_100375	GST C-terminal domain-containing protein. (204 aa)
	CDV56_104238	Uncharacterized protein; Belongs to the GST superfamily. (275 aa)
	CDV56_101189	Uncharacterized protein. (177 aa)
	CDV56_102541	Aminopeptidase. (879 aa)
	CDV56_102892	Uncharacterized protein; Belongs to the GST superfamily. (240 aa)
	GCS1	Zn finger-containing GTPase-Activating Protein for ARF. (670 aa)
	CDV56_104326	Uncharacterized protein; Belongs to the GST superfamily. (237 aa)
	CDV56_105132	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (276 aa)
	CDV56_103776	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (511 aa)
	GND1	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (508 aa)
	CDV56_102449	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (501 aa)
	CDV56_104718	SH3 domain-containing protein. (470 aa)
	CDV56_105383	Uncharacterized protein. (254 aa)
	CDV56_102086	CsbD domain-containing protein. (176 aa)
	CDV56_101944	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (517 aa)
	CDV56_102483	Aldo_ket_red domain-containing protein. (301 aa)
	CDV56_101397	Uncharacterized protein. (602 aa)
	CDV56_102427	Glutathione S-transferase kappa. (223 aa)
	RNR2	Ribonucleotide-diphosphate reductase (RNR), small subunit. (405 aa)
	CDV56_105650	M20_dimer domain-containing protein. (538 aa)
	CDV56_107007	Uncharacterized protein. (708 aa)
	CDV56_106274	Uncharacterized protein; Belongs to the GST superfamily. (256 aa)
	CDV56_105562	Uncharacterized protein; Belongs to the GST superfamily. (287 aa)
	CDV56_101168	Uncharacterized protein; Belongs to the GST superfamily. (255 aa)
	HYR1	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (189 aa)
	RNR1	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (859 aa)
	CDV56_107399	Uncharacterized protein. (417 aa)
	CDV56_100421	Uncharacterized protein. (248 aa)
	CDV56_107894	Uncharacterized protein. (263 aa)
	CDV56_100018	Uncharacterized protein. (151 aa)
	CDV56_103954	Fe2OG dioxygenase domain-containing protein. (244 aa)
	CDV56_105372	Uncharacterized protein; Belongs to the GST superfamily. (262 aa)
	CDV56_107652	Peroxidase; Belongs to the peroxidase family. (320 aa)
	CDV56_106266	Uncharacterized protein; Belongs to the GST superfamily. (235 aa)
	CDV56_105861	Uncharacterized protein. (245 aa)
	CDV56_103145	Uncharacterized protein. (450 aa)
	CCP1	Peroxidase; Belongs to the peroxidase family. (369 aa)
	SPE3	Putrescine aminopropyltransferase; Belongs to the spermidine/spermine synthase family. (251 aa)
	CDV56_107592	Uncharacterized protein. (181 aa)
	CDV56_108693	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (554 aa)
	PRX1_2	Peroxiredoxin 1. (267 aa)
	CDV56_108940	Glutaredoxin domain-containing protein. (183 aa)
	CDV56_107193	Uncharacterized protein. (559 aa)
	CDV56_109208	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (1693 aa)
	CDV56_107400	Uncharacterized protein. (1279 aa)
	PRX1_1	Peroxiredoxin 1. (223 aa)
	CDV56_108910	Uncharacterized protein. (463 aa)
	CDV56_109214	Uncharacterized protein. (327 aa)
	CDV56_109607	GST N-terminal domain-containing protein. (231 aa)
	CDV56_109562	Uncharacterized protein. (1361 aa)
	MT2	Sphingolipid C9-methyltransferase 2. (519 aa)
	CDV56_104281	Isochorismatase domain-containing protein. (394 aa)
	CDV56_107094	F-box domain-containing protein. (726 aa)
	CDV56_108544	Glutaredoxin domain-containing protein. (257 aa)
	CDV56_102443	Uncharacterized protein. (262 aa)
	CDV56_109695	Uncharacterized protein; Belongs to the GST superfamily. (697 aa)
	CDV56_104919	Uncharacterized protein; Belongs to the GST superfamily. (221 aa)
	CDV56_109418	Zn(2)-C6 fungal-type domain-containing protein. (644 aa)
	CDV56_109566	Uncharacterized protein. (871 aa)

Your Current Organism:

Aspergillus thermomutatus

NCBI taxonomy Id: 41047
Other names: A. thermomutatus, Aspergillus fischeri var. thermomutatus, CBS 208.92, NRRL 20748, Neosartorya pseudofischeri

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCP1	CDV56_108693	A0A397H8E2	A0A397HF59	Peroxidase; Belongs to the peroxidase family.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.598
CCP1	CDV56_109214	A0A397H8E2	A0A397HU03	Peroxidase; Belongs to the peroxidase family.	Uncharacterized protein.	0.450
CDV56_100224	CDV56_108693	A0A397G076	A0A397HF59	GST N-terminal domain-containing protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.464
CDV56_100224	CDV56_109214	A0A397G076	A0A397HU03	GST N-terminal domain-containing protein.	Uncharacterized protein.	0.441
CDV56_100224	HYR1	A0A397G076	A0A397GRQ7	GST N-terminal domain-containing protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.479
CDV56_100375	CDV56_101168	A0A397G4F1	A0A397GRK0	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.494
CDV56_100375	CDV56_101397	A0A397G4F1	A0A397GFM9	GST C-terminal domain-containing protein.	Uncharacterized protein.	0.868
CDV56_100375	CDV56_101887	A0A397G4F1	A0A397G1U1	GST C-terminal domain-containing protein.	Thioredoxin domain-containing protein.	0.838
CDV56_100375	CDV56_102440	A0A397G4F1	A0A397G2V9	GST C-terminal domain-containing protein.	Glutathione synthetase.	0.888
CDV56_100375	CDV56_104238	A0A397G4F1	A0A397G5J4	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.494
CDV56_100375	CDV56_104326	A0A397G4F1	A0A397G7C2	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.540
CDV56_100375	CDV56_105562	A0A397G4F1	A0A397GQP8	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.622
CDV56_100375	CDV56_105861	A0A397G4F1	A0A397H400	GST C-terminal domain-containing protein.	Uncharacterized protein.	0.656
CDV56_100375	CDV56_106274	A0A397G4F1	A0A397GQA7	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.494
CDV56_100375	CDV56_107894	A0A397G4F1	A0A397GX32	GST C-terminal domain-containing protein.	Uncharacterized protein.	0.439
CDV56_100375	CDV56_108693	A0A397G4F1	A0A397HF59	GST C-terminal domain-containing protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.888
CDV56_100375	CDV56_109214	A0A397G4F1	A0A397HU03	GST C-terminal domain-containing protein.	Uncharacterized protein.	0.441
CDV56_100375	CDV56_109566	A0A397G4F1	A0A397I3I2	GST C-terminal domain-containing protein.	Uncharacterized protein.	0.866
CDV56_100375	CDV56_109695	A0A397G4F1	A0A397HZ64	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.664
CDV56_100375	HYR1	A0A397G4F1	A0A397GRQ7	GST C-terminal domain-containing protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.548