(14 nodes) MAPK cascade, and Negative regulation of MAPK cascade network (Aspergillus candidus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2I2EXX2	Uncharacterized protein. (720 aa)
	A0A2I2EXX9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (422 aa)
	A0A2I2F1X2	Phosphatase 2C-domain-containing protein. (339 aa)
	A0A2I2F2M4	DUF1857-domain-containing protein. (163 aa)
	A0A2I2F5B5	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (354 aa)
	A0A2I2F698	Serine/threonine protein kinase. (1526 aa)
	A0A2I2F761	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
	A0A2I2FA67	MAP kinase SakA. (373 aa)
	A0A2I2FBL1	PP2C-domain-containing protein. (585 aa)
	A0A2I2FCN5	MADS-box domain-containing protein. (607 aa)
	A0A2I2FEV7	Pleckstrin homology domain-domain-containing protein. (1014 aa)
	A0A2I2FFE8	Protein kinase-like protein. (514 aa)
	A0A2I2FL16	Alternative oxidase. (351 aa)
	A0A2I2FN22	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (495 aa)

Your Current Organism:

Aspergillus candidus

NCBI taxonomy Id: 41067
Other names: A. candidus, CBS 566.65

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2I2EXX2	A0A2I2EXX9	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.986
A0A2I2EXX2	A0A2I2F2M4	Uncharacterized protein.	DUF1857-domain-containing protein.	0.914
A0A2I2EXX2	A0A2I2F5B5	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.980
A0A2I2EXX2	A0A2I2F698	Uncharacterized protein.	Serine/threonine protein kinase.	0.585
A0A2I2EXX2	A0A2I2F761	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.646
A0A2I2EXX2	A0A2I2FA67	Uncharacterized protein.	MAP kinase SakA.	0.646
A0A2I2EXX2	A0A2I2FBL1	Uncharacterized protein.	PP2C-domain-containing protein.	0.453
A0A2I2EXX2	A0A2I2FCN5	Uncharacterized protein.	MADS-box domain-containing protein.	0.485
A0A2I2EXX2	A0A2I2FEV7	Uncharacterized protein.	Pleckstrin homology domain-domain-containing protein.	0.477
A0A2I2EXX2	A0A2I2FFE8	Uncharacterized protein.	Protein kinase-like protein.	0.481
A0A2I2EXX2	A0A2I2FL16	Uncharacterized protein.	Alternative oxidase.	0.449
A0A2I2EXX2	A0A2I2FN22	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.475
A0A2I2EXX9	A0A2I2EXX2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.986
A0A2I2EXX9	A0A2I2F1X2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Phosphatase 2C-domain-containing protein.	0.687
A0A2I2EXX9	A0A2I2F5B5	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.691
A0A2I2EXX9	A0A2I2F698	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Serine/threonine protein kinase.	0.931
A0A2I2EXX9	A0A2I2F761	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.430
A0A2I2EXX9	A0A2I2FA67	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MAP kinase SakA.	0.466
A0A2I2EXX9	A0A2I2FBL1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	PP2C-domain-containing protein.	0.800
A0A2I2EXX9	A0A2I2FCN5	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MADS-box domain-containing protein.	0.972