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| | A0A2I2EXS4 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (521 aa) |
| | A0A2I2EXT1 | MutL_C domain-containing protein. (910 aa) |
| | A0A2I2EXT2 | Putative exonuclease. (733 aa) |
| | A0A2I2EY59 | DNA replication complex GINS protein psf3. (178 aa) |
| | A0A2I2EY73 | Mating-type switching protein swi10. (325 aa) |
| | A0A2I2EY77 | Cnn_1N domain-containing protein. (1004 aa) |
| | A0A2I2EYG2 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa) |
| | A0A2I2EYJ7 | Putative origin recognition complex subunit Orc4. (696 aa) |
| | A0A2I2EYK9 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (272 aa) |
| | A0A2I2EYP6 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (857 aa) |
| | A0A2I2EZ27 | Uncharacterized protein. (242 aa) |
| | A0A2I2EZ43 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (783 aa) |
| | A0A2I2EZ78 | Zf-primase domain-containing protein. (833 aa) |
| | A0A2I2EZT8 | RPA_C domain-containing protein. (287 aa) |
| | A0A2I2F0D3 | Putative origin recognition complex subunit 2. (550 aa) |
| | A0A2I2F0Z3 | Uncharacterized protein. (1829 aa) |
| | A0A2I2F1H4 | Activator 1 37 kDa subunit. (352 aa) |
| | A0A2I2F1Z1 | Putative DNA mismatch repair protein Msh5. (871 aa) |
| | A0A2I2F2D2 | Rad51 domain-containing protein. (407 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (812 aa) |
| | A0A2I2F386 | DNA/RNA polymerase. (558 aa) |
| | A0A2I2F388 | P-loop containing nucleoside triphosphate hydrolase protein. (883 aa) |
| | A0A2I2F3D6 | P-loop containing nucleoside triphosphate hydrolase protein. (397 aa) |
| | A0A2I2F3X7 | Zn(2)-C6 fungal-type domain-containing protein. (424 aa) |
| | A0A2I2F4D4 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (601 aa) |
| | A0A2I2F4F1 | DNA polymerase epsilon subunit B. (746 aa) |
| | A0A2I2F4T4 | Origin recognition complex, subunit 6. (438 aa) |
| | A0A2I2F5A6 | Vacuolar protein 14 C-terminal Fig4p binding-domain-containing protein. (1725 aa) |
| | A0A2I2F5R4 | PIN domain-like protein. (1084 aa) |
| | SLX1 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (353 aa) |
| | A0A2I2F5Y3 | Uncharacterized protein. (569 aa) |
| | A0A2I2F5Y8 | DNA mismatch repair protein Msh1. (1019 aa) |
| | A0A2I2F689 | Uncharacterized protein. (367 aa) |
| | A0A2I2F6B8 | Putative nuclear transport factor NTF-2. (126 aa) |
| | A0A2I2F6D7 | Uncharacterized protein. (158 aa) |
| | A0A2I2F6K8 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (867 aa) |
| | A0A2I2F6L2 | P-loop containing nucleoside triphosphate hydrolase protein. (375 aa) |
| | A0A2I2F6Q4 | DEAD box-containing helicase-like transcription factor/DNA repair protein. (1495 aa) |
| | A0A2I2F729 | SNF2 family N-terminal domain-domain-containing protein. (888 aa) |
| | A0A2I2F770 | RECA_2 domain-containing protein. (887 aa) |
| | A0A2I2F7N9 | Ribonuclease H-like protein. (299 aa) |
| | A0A2I2F7P2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1439 aa) |
| | A0A2I2F7P5 | Cell division control protein; Belongs to the CDC6/cdc18 family. (635 aa) |
| | A0A2I2F7W5 | Uncharacterized protein. (734 aa) |
| | A0A2I2F8J7 | UVSB PI-3 kinase; Belongs to the PI3/PI4-kinase family. (2460 aa) |
| | A0A2I2F8L9 | Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (286 aa) |
| | A0A2I2F8P7 | DNA topoisomerase I-interacting protein. (1170 aa) |
| | A0A2I2F914 | DNA mismatch repair protein. (887 aa) |
| | A0A2I2F995 | Origin recognition complex, subunit 3. (694 aa) |
| | A0A2I2F9A1 | DNA repair protein Rhp26/Rad26. (1207 aa) |
| | A0A2I2F9F9 | Putative DNA repair protein RAD1. (979 aa) |
| | A0A2I2F9L3 | DNA repair protein. (365 aa) |
| | A0A2I2F9L9 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (790 aa) |
| | A0A2I2F9W6 | Putative dsDNA-dependent ATPase. (970 aa) |
| | A0A2I2FAA6 | DNA/RNA polymerase. (599 aa) |
| | A0A2I2FAI6 | Uncharacterized protein. (290 aa) |
| | A0A2I2FAQ8 | Rad51-domain-containing protein; Belongs to the RecA family. (326 aa) |
| | A0A2I2FAU2 | Rad9-domain-containing protein. (553 aa) |
| | A0A2I2FAV3 | DNA polymerase. (1985 aa) |
| | A0A2I2FBH1 | Putative sister chromatid cohesion protein. (657 aa) |
| | A0A2I2FBN0 | Subunit of DNA polymerase II. (824 aa) |
| | A0A2I2FBQ0 | ERCC4 domain-domain-containing protein. (596 aa) |
| | A0A2I2FBR7 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (655 aa) |
| | A0A2I2FBU1 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2893 aa) |
| | A0A2I2FBX2 | Ribonucleoside-diphosphate reductase small chain. (401 aa) |
| | A0A2I2FBY8 | Uncharacterized protein. (328 aa) |
| | A0A2I2FC99 | Ctf8-domain-containing protein. (345 aa) |
| | A0A2I2FCL6 | Replication factor C subunit 2. (390 aa) |
| | A0A2I2FCU6 | Exonuclease. (574 aa) |
| | A0A2I2FCV0 | Putative RecQ-mediated genome instability protein. (244 aa) |
| | A0A2I2FCY5 | DNA repair protein Mus81. (590 aa) |
| | A0A2I2FDL5 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1206 aa) |
| | A0A2I2FDM6 | DNA polymerase delta subunit 2. (532 aa) |
| | A0A2I2FDS4 | Uncharacterized protein. (492 aa) |
| | A0A2I2FDT9 | DNA repair protein RAD50, ABC-type ATPase/SMC superfamily. (1301 aa) |
| | A0A2I2FE06 | DRMBL-domain-containing protein. (840 aa) |
| | A0A2I2FE84 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (560 aa) |
| | A0A2I2FEA8 | Uncharacterized protein. (608 aa) |
| | A0A2I2FEB1 | Uncharacterized protein. (385 aa) |
| | A0A2I2FF21 | SAE2-domain-containing protein. (690 aa) |
| | A0A2I2FF25 | WD40 repeat-like protein. (838 aa) |
| | A0A2I2FF29 | DNA polymerase. (1674 aa) |
| | A0A2I2FFB8 | Linker histone H1 and H5 family-domain-containing protein. (199 aa) |
| | A0A2I2FFJ8 | Putative cell cycle protein kinase. (492 aa) |
| | A0A2I2FFL6 | RRM domain-containing protein. (316 aa) |
| | A0A2I2FFR5 | DNA helicase; Belongs to the MCM family. (1830 aa) |
| | A0A2I2FFW0 | Replication factor C subunit 1. (1046 aa) |
| | A0A2I2FFW1 | Cytochrome c oxidase assembly protein CtaG/Cox11-domain-containing protein. (607 aa) |
| | A0A2I2FG11 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1149 aa) |
| | A0A2I2FG90 | G1/S regulator NimO. (645 aa) |
| | A0A2I2FGJ6 | Asparaginyl-tRNA synthetase. (570 aa) |
| | A0A2I2FH29 | DNA replication regulator SLD3-domain-containing protein. (972 aa) |
| | A0A2I2FH39 | Histone-fold-containing protein. (328 aa) |
| | A0A2I2FH61 | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (347 aa) |
| | A0A2I2FHP6 | Putative DNA mismatch repair protein. (1071 aa) |
| | A0A2I2FHS1 | Stn1 domain-containing protein. (252 aa) |
| | A0A2I2FHS2 | MAPK related serine/threonine protein kinase. (780 aa) |
| | A0A2I2FIU8 | Postreplication repair E3 ubiquitin-protein ligase rad18. (423 aa) |
| | A0A2I2FIV0 | DNA polymerase subunit Cdc27. (453 aa) |
| | A0A2I2FIV8 | DNA polymerase. (1105 aa) |
| | A0A2I2FJ40 | Putative sister chromatid cohesion protein Dcc1. (419 aa) |
| | A0A2I2FJ43 | DNA helicase; Belongs to the MCM family. (894 aa) |
| | A0A2I2FJ52 | DNA-binding protein. (277 aa) |
| | A0A2I2FJP4 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2230 aa) |
| | A0A2I2FJP6 | Muts domain V-domain-containing protein. (1647 aa) |
| | A0A2I2FK18 | MRC1-like domain-domain-containing protein. (1301 aa) |
| | A0A2I2FKG3 | Checkpoint protein; Belongs to the HUS1 family. (339 aa) |
| | A0A2I2FKM5 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (275 aa) |
| | A0A2I2FL09 | RecQ family helicase MusN. (1541 aa) |
| | A0A2I2FLD7 | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa) |
| | A0A2I2FLK5 | Uncharacterized protein. (1088 aa) |
| | A0A2I2FLN1 | Origin recognition complex subunit Orc5. (534 aa) |
| | A0A2I2FLQ2 | Muts domain V-domain-containing protein. (923 aa) |
| | A0A2I2FLW8 | SNF2 family N-terminal domain-domain-containing protein. (1191 aa) |
| | A0A2I2FM65 | Acetamidase/formamidase family protein. (329 aa) |
| | A0A2I2FMU1 | MCM-domain-containing protein; Belongs to the MCM family. (2186 aa) |
| | A0A2I2FN08 | Uncharacterized protein. (383 aa) |
| | A0A2I2FN89 | Pkinase-domain-containing protein. (815 aa) |
| | A0A2I2FN96 | DNA mismatch repair protein MutL. (733 aa) |
| | A0A2I2FNJ2 | DNA helicase; Belongs to the MCM family. (968 aa) |
| | A0A2I2FNQ8 | DNA helicase; Belongs to the MCM family. (717 aa) |
| | A0A2I2FNS3 | Cytochrome P450; Belongs to the cytochrome P450 family. (468 aa) |
| | A0A2I2FPE1 | Uncharacterized protein. (518 aa) |
| | A0A2I2FPH4 | Sld5 domain-containing protein. (217 aa) |
| | A0A2I2FPW9 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (816 aa) |
| | A0A2I2FPY3 | Chromosome transmission fidelity protein 18. (1055 aa) |
