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A0A2I2F942 A0A2I2F942 A0A2I2EYB5 A0A2I2EYB5 MED5 MED5 A0A2I2EYT6 A0A2I2EYT6 A0A2I2EYT9 A0A2I2EYT9 A0A2I2EZH9 A0A2I2EZH9 A0A2I2EZQ5 A0A2I2EZQ5 A0A2I2F065 A0A2I2F065 A0A2I2F0J4 A0A2I2F0J4 A0A2I2F115 A0A2I2F115 A0A2I2F129 A0A2I2F129 A0A2I2F1E3 A0A2I2F1E3 A0A2I2F1G0 A0A2I2F1G0 A0A2I2F1K8 A0A2I2F1K8 A0A2I2F1P1 A0A2I2F1P1 MED17 MED17 A0A2I2F366 A0A2I2F366 A0A2I2F3G8 A0A2I2F3G8 A0A2I2F3U6 A0A2I2F3U6 A0A2I2F4L5 A0A2I2F4L5 A0A2I2F4N1 A0A2I2F4N1 A0A2I2F570 A0A2I2F570 A0A2I2F683 A0A2I2F683 MED18 MED18 A0A2I2F7C0 A0A2I2F7C0 A0A2I2F8Q2 A0A2I2F8Q2 A0A2I2F957 A0A2I2F957 A0A2I2F9T5 A0A2I2F9T5 A0A2I2FA01 A0A2I2FA01 A0A2I2FAB0 A0A2I2FAB0 A0A2I2FAV6 A0A2I2FAV6 A0A2I2FB14 A0A2I2FB14 A0A2I2FBI6 A0A2I2FBI6 A0A2I2FBW9 A0A2I2FBW9 A0A2I2FCA3 A0A2I2FCA3 MED8 MED8 A0A2I2FF39 A0A2I2FF39 A0A2I2FF85 A0A2I2FF85 A0A2I2FFZ1 A0A2I2FFZ1 A0A2I2FGK8 A0A2I2FGK8 A0A2I2FGT2 A0A2I2FGT2 A0A2I2FHE8 A0A2I2FHE8 A0A2I2FHJ3 A0A2I2FHJ3 A0A2I2FHQ3 A0A2I2FHQ3 A0A2I2FHX1 A0A2I2FHX1 A0A2I2FI41 A0A2I2FI41 A0A2I2FIF2 A0A2I2FIF2 A0A2I2FJ75 A0A2I2FJ75 A0A2I2FJL7 A0A2I2FJL7 A0A2I2FKB9 A0A2I2FKB9 A0A2I2FKZ2 A0A2I2FKZ2 A0A2I2FL25 A0A2I2FL25 A0A2I2FL36 A0A2I2FL36 A0A2I2FLT4 A0A2I2FLT4 A0A2I2FMK5 A0A2I2FMK5 MED10 MED10 A0A2I2FP20 A0A2I2FP20 A0A2I2FP27 A0A2I2FP27 A0A2I2FP41 A0A2I2FP41
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A2I2F942HDAC_interact domain-containing protein. (1624 aa)
A0A2I2EYB5Sin3 associated polypeptide p18-domain-containing protein. (281 aa)
MED5Mediator of RNA polymerase II transcription subunit 5; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (907 aa)
A0A2I2EYT6SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...] (271 aa)
A0A2I2EYT9C2HC5 finger protein. (528 aa)
A0A2I2EZH9Spt20 family-domain-containing protein. (948 aa)
A0A2I2EZQ5Uncharacterized protein. (184 aa)
A0A2I2F065SWI-SNF chromatin remodeling complex, Snf5 subunit. (567 aa)
A0A2I2F0J4TFIID-18kDa-domain-containing protein. (372 aa)
A0A2I2F115Putative SNF2 family helicase. (915 aa)
A0A2I2F129SP-RING-type domain-containing protein. (1038 aa)
A0A2I2F1E3DNA methyltransferase 1-associated protein DMAP1. (599 aa)
A0A2I2F1G0Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (321 aa)
A0A2I2F1K8WD40 repeat-like protein. (585 aa)
A0A2I2F1P1WD40 repeat-like protein. (612 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (628 aa)
A0A2I2F366Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1086 aa)
A0A2I2F3G8Uncharacterized protein. (234 aa)
A0A2I2F3U6Transcription initiation factor IID, 31kD subunit-domain-containing protein. (319 aa)
A0A2I2F4L5Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1088 aa)
A0A2I2F4N1Putative PHD finger and JmjC domain protein. (1431 aa)
A0A2I2F570Opi1-domain-containing protein. (503 aa)
A0A2I2F683Uncharacterized protein. (264 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (271 aa)
A0A2I2F7C0Alpha/beta-hydrolase. (553 aa)
A0A2I2F8Q2Putative SWI-SNF complex subunit. (750 aa)
A0A2I2F957FAS1 domain-containing protein. (240 aa)
A0A2I2F9T5DUF1014-domain-containing protein. (223 aa)
A0A2I2FA01TATA element modulatory factor 1 TATA binding-domain-containing protein. (851 aa)
A0A2I2FAB0Uncharacterized protein. (140 aa)
A0A2I2FAV6Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (518 aa)
A0A2I2FB14Uncharacterized protein. (483 aa)
A0A2I2FBI6Transcription factor. (638 aa)
A0A2I2FBW9Heat shock factor binding protein 1-domain-containing protein. (84 aa)
A0A2I2FCA3Uncharacterized protein. (1439 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (284 aa)
A0A2I2FF39Putative COP9 signalosome subunit 2. (501 aa)
A0A2I2FF85Mediator of RNA polymerase II transcription subunit 12. (1587 aa)
A0A2I2FFZ1Putative transcriptional corepressor Cyc8. (865 aa)
A0A2I2FGK8WD40-repeat-containing domain protein. (268 aa)
A0A2I2FGT2DUF3835 domain-containing protein. (583 aa)
A0A2I2FHE8Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1071 aa)
A0A2I2FHJ3Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (427 aa)
A0A2I2FHQ3Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (195 aa)
A0A2I2FHX1LIM-domain binding protein-domain-containing protein. (847 aa)
A0A2I2FI41CBFD_NFYB_HMF domain-containing protein. (303 aa)
A0A2I2FIF2Fungal-specific transcription factor domain-domain-containing protein. (716 aa)
A0A2I2FJ75Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (153 aa)
A0A2I2FJL7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (365 aa)
A0A2I2FKB9Uncharacterized protein. (210 aa)
A0A2I2FKZ2Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (256 aa)
A0A2I2FL25Uncharacterized protein. (1527 aa)
A0A2I2FL36Mediator of RNA polymerase II transcription subunit 13; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. (1490 aa)
A0A2I2FLT4WD40 repeat-like protein. (480 aa)
A0A2I2FMK5Histone acetyltransferases subunit 3-domain-containing protein. (676 aa)
MED10Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (154 aa)
A0A2I2FP20Transcription initiation factor TFIID complex subunit. (445 aa)
A0A2I2FP27HTAFII28-like protein conserved region-domain-containing protein. (364 aa)
A0A2I2FP41Putative RNA polymerase II transcriptional coactivator. (167 aa)
Your Current Organism:
Aspergillus candidus
NCBI taxonomy Id: 41067
Other names: A. candidus, CBS 566.65
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