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A0A2I2FMM3 A0A2I2FMM3 A0A2I2FAX3 A0A2I2FAX3 A0A2I2FB16 A0A2I2FB16 A0A2I2FB42 A0A2I2FB42 A0A2I2FC88 A0A2I2FC88 DRE2 DRE2 A0A2I2FE01 A0A2I2FE01 A0A2I2FED1 A0A2I2FED1 A0A2I2FER9 A0A2I2FER9 A0A2I2FES3 A0A2I2FES3 A0A2I2FEX4 A0A2I2FEX4 A0A2I2FEZ7 A0A2I2FEZ7 A0A2I2FF29 A0A2I2FF29 A0A2I2FF48 A0A2I2FF48 A0A2I2FFR9 A0A2I2FFR9 A0A2I2FH98 A0A2I2FH98 A0A2I2FHY2 A0A2I2FHY2 A0A2I2FI15 A0A2I2FI15 A0A2I2FIV8 A0A2I2FIV8 A0A2I2FIZ1 A0A2I2FIZ1 NBP35 NBP35 A0A2I2FJ96 A0A2I2FJ96 A0A2I2FJP4 A0A2I2FJP4 A0A2I2FKC5 A0A2I2FKC5 A0A2I2FKD8 A0A2I2FKD8 A0A2I2FLD7 A0A2I2FLD7 A0A2I2FMG1 A0A2I2FMG1 A0A2I2FMH6 A0A2I2FMH6 A0A2I2FAQ6 A0A2I2FAQ6 A0A2I2FMW9 A0A2I2FMW9 CFD1 CFD1 A0A2I2FPC2 A0A2I2FPC2 A0A2I2FPE1 A0A2I2FPE1 NTH1 NTH1 A0A2I2F5S8 A0A2I2F5S8 A0A2I2F5W2 A0A2I2F5W2 A0A2I2F725 A0A2I2F725 A0A2I2F7F0 A0A2I2F7F0 A0A2I2F8G5 A0A2I2F8G5 A0A2I2F8T6 A0A2I2F8T6 A0A2I2F5F5 A0A2I2F5F5 A0A2I2F2D4 A0A2I2F2D4 A0A2I2F8X7 A0A2I2F8X7 A0A2I2F9B7 A0A2I2F9B7 A0A2I2F9I0 A0A2I2F9I0 A0A2I2FA51 A0A2I2FA51 A0A2I2FAA1 A0A2I2FAA1 A0A2I2EYF2 A0A2I2EYF2 A0A2I2F2M5 A0A2I2F2M5 A0A2I2EZ60 A0A2I2EZ60 A0A2I2EZJ3 A0A2I2EZJ3 A0A2I2EZS1 A0A2I2EZS1 A0A2I2F064 A0A2I2F064 A0A2I2F083 A0A2I2F083 A0A2I2F0H0 A0A2I2F0H0 A0A2I2F0H6 A0A2I2F0H6 A0A2I2F0P5 A0A2I2F0P5 CIA1 CIA1 A0A2I2F213 A0A2I2F213 A0A2I2F3C1 A0A2I2F3C1 A0A2I2F3D2 A0A2I2F3D2 A0A2I2F3Q6 A0A2I2F3Q6 A0A2I2F4X7 A0A2I2F4X7 A0A2I2F588 A0A2I2F588 A0A2I2FAQ2 A0A2I2FAQ2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A2I2FMM3HIRA-interacting protein 5. (324 aa)
A0A2I2FAX3Uncharacterized protein. (80 aa)
A0A2I2FB16NADH-ubiquinone oxidoreductase 49 kDa subunit mitochondrial; Belongs to the complex I 49 kDa subunit family. (476 aa)
A0A2I2FB42MmgE/PrpD family protein. (481 aa)
A0A2I2FC88Putative conserved membrane protein. (581 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (302 aa)
A0A2I2FE01Sulfite reductase beta subunit. (1530 aa)
A0A2I2FED1Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (201 aa)
A0A2I2FER92-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily. (581 aa)
A0A2I2FES3Uncharacterized protein. (840 aa)
A0A2I2FEX4Glutamate synthase Glt1. (2126 aa)
A0A2I2FEZ7Putative dihydroxy-acid dehydratase. (609 aa)
A0A2I2FF29DNA polymerase. (1674 aa)
A0A2I2FF48Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (415 aa)
A0A2I2FFR9Putative NADH-ubiquinone dehydrogenase 24 kDa subunit. (272 aa)
A0A2I2FH98Putative ATP-binding cassette sub-family E member 1. (363 aa)
A0A2I2FHY22-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (435 aa)
A0A2I2FI15Uncharacterized protein. (805 aa)
A0A2I2FIV8DNA polymerase. (1105 aa)
A0A2I2FIZ1Putative dihydroxy acid dehydratase. (655 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (337 aa)
A0A2I2FJ96Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (278 aa)
A0A2I2FJP4DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2230 aa)
A0A2I2FKC5Uncharacterized protein. (391 aa)
A0A2I2FKD82-methylcitrate dehydratase. (558 aa)
A0A2I2FLD7DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
A0A2I2FMG1Iron-sulfur protein IND1. (326 aa)
A0A2I2FMH6Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (775 aa)
A0A2I2FAQ6Putative AIF-like mitochondrial oxidoreductase. (556 aa)
A0A2I2FMW9Dihydroxy-acid dehydratase. (609 aa)
CFD1Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (716 aa)
A0A2I2FPC2Iron hydrogenase; Belongs to the NARF family. (597 aa)
A0A2I2FPE1Uncharacterized protein. (518 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (893 aa)
A0A2I2F5S8Bola-like protein; Belongs to the BolA/IbaG family. (130 aa)
A0A2I2F5W2Molybdenum cofactor biosynthesis prote. (699 aa)
A0A2I2F725Rieske domain-containing protein. (1101 aa)
A0A2I2F7F023 kDa subunit of NADH-quinone oxidoreductase. (222 aa)
A0A2I2F8G5TLDc domain-containing protein. (549 aa)
A0A2I2F8T6Uncharacterized protein. (390 aa)
A0A2I2F5F5Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (786 aa)
A0A2I2F2D4Cysteine desulfurase. (504 aa)
A0A2I2F8X7Glutaredoxin. (273 aa)
A0A2I2F9B7Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (802 aa)
A0A2I2F9I0Frataxin-like domain-containing protein. (209 aa)
A0A2I2FA51Xanthine dehydrogenase. (1404 aa)
A0A2I2FAA1TLDc domain-containing protein. (523 aa)
A0A2I2EYF22Fe-2S iron-sulfur cluster binding domain protein. (209 aa)
A0A2I2F2M5Putative dihydroxy-acid dehydratase. (598 aa)
A0A2I2EZ60Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (634 aa)
A0A2I2EZJ3NADH-quinone oxidoreductase; Belongs to the complex I 75 kDa subunit family. (737 aa)
A0A2I2EZS1Fe-S oxidoreductase. (782 aa)
A0A2I2F064Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (152 aa)
A0A2I2F083Putative NADH-ubiquinone oxidoreductase subunit B; Belongs to the complex I 20 kDa subunit family. (228 aa)
A0A2I2F0H0Uncharacterized protein. (627 aa)
A0A2I2F0H6DNA repair helicase RAD3. (795 aa)
A0A2I2F0P53-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (773 aa)
CIA1Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (435 aa)
A0A2I2F213Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (578 aa)
A0A2I2F3C1Xanthine dehydrogenase. (1362 aa)
A0A2I2F3D2NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (494 aa)
A0A2I2F3Q6Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (239 aa)
A0A2I2F4X7Putative mitochondrial dihydroxy acid dehydratase. (611 aa)
A0A2I2F588Aconitase_C domain-containing protein. (160 aa)
A0A2I2FAQ2Uncharacterized protein. (714 aa)
Your Current Organism:
Aspergillus candidus
NCBI taxonomy Id: 41067
Other names: A. candidus, CBS 566.65
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