STRINGSTRING
A0A2I2EXS4 A0A2I2EXS4 A0A2I2EY59 A0A2I2EY59 A0A2I2EY77 A0A2I2EY77 A0A2I2EYD6 A0A2I2EYD6 A0A2I2EYJ7 A0A2I2EYJ7 A0A2I2EYK9 A0A2I2EYK9 A0A2I2EZ78 A0A2I2EZ78 A0A2I2EZT8 A0A2I2EZT8 A0A2I2F041 A0A2I2F041 A0A2I2F0D3 A0A2I2F0D3 A0A2I2F1H4 A0A2I2F1H4 A0A2I2F228 A0A2I2F228 A0A2I2F249 A0A2I2F249 A0A2I2F2M3 A0A2I2F2M3 MCM7 MCM7 A0A2I2F3D6 A0A2I2F3D6 A0A2I2F4D4 A0A2I2F4D4 A0A2I2F4F1 A0A2I2F4F1 A0A2I2F4T4 A0A2I2F4T4 A0A2I2F4V8 A0A2I2F4V8 A0A2I2F630 A0A2I2F630 A0A2I2F646 A0A2I2F646 A0A2I2F6K8 A0A2I2F6K8 A0A2I2F7P5 A0A2I2F7P5 A0A2I2F8I2 A0A2I2F8I2 A0A2I2F995 A0A2I2F995 A0A2I2F9L9 A0A2I2F9L9 A0A2I2FAV3 A0A2I2FAV3 A0A2I2FBR7 A0A2I2FBR7 A0A2I2FBT2 A0A2I2FBT2 A0A2I2FC73 A0A2I2FC73 A0A2I2FCL6 A0A2I2FCL6 A0A2I2FCS0 A0A2I2FCS0 A0A2I2FCY1 A0A2I2FCY1 A0A2I2FDM6 A0A2I2FDM6 A0A2I2FEM2 A0A2I2FEM2 A0A2I2FFJ8 A0A2I2FFJ8 A0A2I2FFL8 A0A2I2FFL8 A0A2I2FFR5 A0A2I2FFR5 A0A2I2FFS7 A0A2I2FFS7 A0A2I2FFW0 A0A2I2FFW0 A0A2I2FFW1 A0A2I2FFW1 A0A2I2FG90 A0A2I2FG90 A0A2I2FH39 A0A2I2FH39 A0A2I2FHH8 A0A2I2FHH8 A0A2I2FHR8 A0A2I2FHR8 A0A2I2FIV0 A0A2I2FIV0 A0A2I2FIV8 A0A2I2FIV8 A0A2I2FJ06 A0A2I2FJ06 A0A2I2FJ14 A0A2I2FJ14 A0A2I2FJ43 A0A2I2FJ43 A0A2I2FJ95 A0A2I2FJ95 A0A2I2FJP4 A0A2I2FJP4 A0A2I2FKM5 A0A2I2FKM5 A0A2I2FKP7 A0A2I2FKP7 A0A2I2FKS7 A0A2I2FKS7 A0A2I2FLD7 A0A2I2FLD7 A0A2I2FLN1 A0A2I2FLN1 FEN1 FEN1 A0A2I2FMU1 A0A2I2FMU1 A0A2I2FMY4 A0A2I2FMY4 A0A2I2FNJ2 A0A2I2FNJ2 A0A2I2FNM5 A0A2I2FNM5 A0A2I2FNP7 A0A2I2FNP7 A0A2I2FNQ8 A0A2I2FNQ8 A0A2I2FPD5 A0A2I2FPD5 A0A2I2FPE1 A0A2I2FPE1 A0A2I2FPH4 A0A2I2FPH4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A2I2EXS4DNA primase; Belongs to the eukaryotic-type primase small subunit family. (521 aa)
A0A2I2EY59DNA replication complex GINS protein psf3. (178 aa)
A0A2I2EY77Cnn_1N domain-containing protein. (1004 aa)
A0A2I2EYD6Pkinase-domain-containing protein; Belongs to the protein kinase superfamily. (374 aa)
A0A2I2EYJ7Putative origin recognition complex subunit Orc4. (696 aa)
A0A2I2EYK9DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (272 aa)
A0A2I2EZ78Zf-primase domain-containing protein. (833 aa)
A0A2I2EZT8RPA_C domain-containing protein. (287 aa)
A0A2I2F041BZIP domain-containing protein. (292 aa)
A0A2I2F0D3Putative origin recognition complex subunit 2. (550 aa)
A0A2I2F1H4Activator 1 37 kDa subunit. (352 aa)
A0A2I2F228UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (448 aa)
A0A2I2F249RING/U-box. (119 aa)
A0A2I2F2M3Uncharacterized protein. (139 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (812 aa)
A0A2I2F3D6P-loop containing nucleoside triphosphate hydrolase protein. (397 aa)
A0A2I2F4D4Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (601 aa)
A0A2I2F4F1DNA polymerase epsilon subunit B. (746 aa)
A0A2I2F4T4Origin recognition complex, subunit 6. (438 aa)
A0A2I2F4V8Uncharacterized protein. (146 aa)
A0A2I2F630DNA ligase. (828 aa)
A0A2I2F646DNA polymerase delta, subunit 4-domain-containing protein. (191 aa)
A0A2I2F6K8Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (867 aa)
A0A2I2F7P5Cell division control protein; Belongs to the CDC6/cdc18 family. (635 aa)
A0A2I2F8I2NLPC_P60 domain-containing protein. (180 aa)
A0A2I2F995Origin recognition complex, subunit 3. (694 aa)
A0A2I2F9L9Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (790 aa)
A0A2I2FAV3DNA polymerase. (1985 aa)
A0A2I2FBR7DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (655 aa)
A0A2I2FBT2Replication factor A protein 3. (127 aa)
A0A2I2FC73Ubiquitin-related domain-containing protein. (305 aa)
A0A2I2FCL6Replication factor C subunit 2. (390 aa)
A0A2I2FCS0Peptidase S8/S53 domain-containing protein. (762 aa)
A0A2I2FCY1Protoporphyrinogen oxidase. (533 aa)
A0A2I2FDM6DNA polymerase delta subunit 2. (532 aa)
A0A2I2FEM2Cyclin-like protein; Belongs to the cyclin family. (416 aa)
A0A2I2FFJ8Putative cell cycle protein kinase. (492 aa)
A0A2I2FFL8Histone H2B; Belongs to the histone H2B family. (141 aa)
A0A2I2FFR5DNA helicase; Belongs to the MCM family. (1830 aa)
A0A2I2FFS7DNA ligase. (880 aa)
A0A2I2FFW0Replication factor C subunit 1. (1046 aa)
A0A2I2FFW1Cytochrome c oxidase assembly protein CtaG/Cox11-domain-containing protein. (607 aa)
A0A2I2FG90G1/S regulator NimO. (645 aa)
A0A2I2FH39Histone-fold-containing protein. (328 aa)
A0A2I2FHH8Uncharacterized protein. (550 aa)
A0A2I2FHR8DnaJ-domain-containing protein. (290 aa)
A0A2I2FIV0DNA polymerase subunit Cdc27. (453 aa)
A0A2I2FIV8DNA polymerase. (1105 aa)
A0A2I2FJ06Putative G2/mitotic-specific cyclin; Belongs to the cyclin family. (627 aa)
A0A2I2FJ14Importin subunit alpha; Belongs to the importin alpha family. (466 aa)
A0A2I2FJ43DNA helicase; Belongs to the MCM family. (894 aa)
A0A2I2FJ95Ubiquitin-related domain-containing protein. (154 aa)
A0A2I2FJP4DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2230 aa)
A0A2I2FKM5DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (275 aa)
A0A2I2FKP7Protein kinase; Belongs to the protein kinase superfamily. (323 aa)
A0A2I2FKS7Zds_C domain-containing protein. (869 aa)
A0A2I2FLD7DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
A0A2I2FLN1Origin recognition complex subunit Orc5. (534 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (359 aa)
A0A2I2FMU1MCM-domain-containing protein; Belongs to the MCM family. (2186 aa)
A0A2I2FMY4Uncharacterized protein. (691 aa)
A0A2I2FNJ2DNA helicase; Belongs to the MCM family. (968 aa)
A0A2I2FNM5Histone-fold-containing protein. (202 aa)
A0A2I2FNP7DNA_LIGASE_A3 domain-containing protein. (1031 aa)
A0A2I2FNQ8DNA helicase; Belongs to the MCM family. (717 aa)
A0A2I2FPD5A/B/D/E cyclin; Belongs to the cyclin family. (480 aa)
A0A2I2FPE1Uncharacterized protein. (518 aa)
A0A2I2FPH4Sld5 domain-containing protein. (217 aa)
Your Current Organism:
Aspergillus candidus
NCBI taxonomy Id: 41067
Other names: A. candidus, CBS 566.65
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