STRINGSTRING
ilvB-2 ilvB-2 EDR47539.1 EDR47539.1 EDR47352.1 EDR47352.1 pflB pflB EDR47141.1 EDR47141.1 EDR47142.1 EDR47142.1 EDR47143.1 EDR47143.1 EDR45577.1 EDR45577.1 EDR45640.1 EDR45640.1 nifJ nifJ ilvN-2 ilvN-2 ilvN ilvN EDR48334.1 EDR48334.1 EDR48333.1 EDR48333.1 EDR48332.1 EDR48332.1 sdhB sdhB sdhA sdhA EDR48335.1 EDR48335.1 EDR47718.1 EDR47718.1 ilvB ilvB EDR47918.1 EDR47918.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ilvB-2Acetolactate synthase, large subunit, biosynthetic type; KEGG: mma:MM0670 1.1e-155 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score: 8.87. (575 aa)
EDR47539.1Putative formate C-acetyltransferase; KEGG: cno:NT01CX_0385 3.1e-144 pyruvate formate-lyase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98. (803 aa)
EDR47352.1Aldehyde dehydrogenase (NAD) family protein; KEGG: cpe:CPE2531 0. adhE; alcohol dehydrogenase / acetaldehyde dehydrogenase K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (868 aa)
pflBKEGG: bli:BL01863 3.6e-269 hypothetical formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98. (769 aa)
EDR47141.1Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (383 aa)
EDR47142.1Biotin-requiring enzyme; KEGG: sph:MGAS10270_Spy1010 2.1e-19 biotin carboxyl carrier protein of oxaloacetate decarboxylase K01570; COG: COG0511 Biotin carboxyl carrier protein. (121 aa)
EDR47143.1Sodium pump decarboxylase, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the OadG family. (245 aa)
EDR45577.1KEGG: cac:CAC2000 2.0e-48 iorB; indolepyruvate ferredoxin oxidoreductase, subunit beta K00180; COG: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; Psort location: Cytoplasmic, score: 8.87. (189 aa)
EDR45640.1Indolepyruvate oxidoreductase subunit B; KEGG: mma:MM2635 1.3e-35 putative pyruvate:ferredoxin oxidoreductase K00180; COG: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; Psort location: Cytoplasmic, score: 8.87. (209 aa)
nifJKEGG: ctc:CTC01741 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87. (1179 aa)
ilvN-2KEGG: noc:Noc_2519 6.8e-30 acetolactate synthase, small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit; Psort location: Cytoplasmic, score: 8.87. (172 aa)
ilvNKEGG: chy:CHY_1594 4.3e-37 ilvN2; acetolactate synthase, small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit; Psort location: Cytoplasmic, score: 8.87. (165 aa)
EDR48334.1Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; KEGG: ctc:CTC02526 2.0e-126 porA; pyruvate synthase subunit porA K00169; COG: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Psort location: Cytoplasmic, score: 8.87. (394 aa)
EDR48333.12-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family; KEGG: cno:NT01CX_0146 4.8e-22 porD; pyruvate synthase subunit PorD K00168; COG: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit; Psort location: Cytoplasmic, score: 8.87. (100 aa)
EDR48332.12-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family; KEGG: cno:NT01CX_0147 5.6e-67 porG; pyruvate synthase subunit PorC K00168; COG: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; Psort location: Cytoplasmic, score: 8.87. (190 aa)
sdhBKEGG: sha:SH1812 1.0e-35 sdhB; succinate dehydrogenase iron-sulfur protein subunit K00240; COG: COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (236 aa)
sdhAKEGG: gka:GK2672 5.6e-83 sdhA; succinate dehydrogenase (flavoprotein subunit) K00239; COG: COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Psort location: Cytoplasmic, score: 9.36. (472 aa)
EDR48335.1Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein; KEGG: ctc:CTC02525 4.2e-101 porB; pyruvate synthase subunit porB K00170; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87. (311 aa)
EDR47718.1Alcohol dehydrogenase, iron-dependent; KEGG: tte:TTE0313 9.2e-90 uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family K00120; COG: COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family; Psort location: Cytoplasmic, score: 9.98. (405 aa)
ilvBAcetolactate synthase, large subunit, biosynthetic type; KEGG: cac:CAC3169 4.9e-171 ilvB; acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score: 8.87. (558 aa)
EDR47918.1KEGG: dra:DRA0143 1.2e-55 3-hydroxyacyl-CoA dehydrogenase, putative K00022; COG: COG1250 3-hydroxyacyl-CoA dehydrogenase. (238 aa)
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.