(12 nodes) Cell differentiation network (Eubacterium ventriosum)

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Your Input:
	gpr	GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. (300 aa)
	spoIIP	Stage II sporulation protein P; KEGG: wbr:WGLp018 0.042 surA; parvulin-like peptidyl-prolyl isomerase K03771; COG: NOG13213 non supervised orthologous group. (412 aa)
	EDM52503.1	RNA polymerase sigma-K factor; KEGG: reh:H16_A1626 2.5e-11 rpoD1; DNA-directed RNA polymerase sigma subunit (RpoD) K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the sigma-70 factor family. (192 aa)
	EDM52118.1	Hypothetical protein; KEGG: ava:Ava_3181 0.0061 site-specific DNA-methyltransferase (cytosine-specific) K00590; COG: NOG05963 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99. (486 aa)
	EDM51440.1	Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (265 aa)
	spoIVB	SpoIVB peptidase; KEGG: btl:BALH_3781 4.6e-56 spoIVB; stage IV sporulation protein B; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1. (409 aa)
	EDM50381.1	KEGG: ava:Ava_0744 1.9e-06 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (109 aa)
	spoIIAB	Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (194 aa)
	EDM50383.1	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; KEGG: hpa:HPAG1_0089 2.1e-16 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family. (237 aa)
	spoVAC	Stage V sporulation protein AC; KEGG: mbu:Mbur_1239 0.24 H+-transporting two-sector ATPase, C subunit K02124; COG: NOG09745 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 7.63. (152 aa)
	spoVAD	Stage V sporulation protein AD; KEGG: cca:CCA00484 0.011 fabH; 3-oxoacyl-(acyl-carrier-protein) synthase III K00648; COG: NOG06312 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 7.63. (336 aa)
	spoVAE	Stage V sporulation protein AE; KEGG: tfu:Tfu_2682 0.37 proton-translocating NADH-quinone oxidoreductase, chain N K00343; COG: NOG13202 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99. (117 aa)

Your Current Organism:

Eubacterium ventriosum

NCBI taxonomy Id: 411463
Other names: E. ventriosum ATCC 27560, Eubacterium ventriosum ATCC 27560

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDM50381.1	EDM50383.1	EUBVEN_02332	EUBVEN_02334	KEGG: ava:Ava_0744 1.9e-06 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; KEGG: hpa:HPAG1_0089 2.1e-16 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.	0.936
EDM50381.1	EDM51440.1	EUBVEN_02332	EUBVEN_01348	KEGG: ava:Ava_0744 1.9e-06 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	0.834
EDM50381.1	EDM52118.1	EUBVEN_02332	EUBVEN_00646	KEGG: ava:Ava_0744 1.9e-06 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	Hypothetical protein; KEGG: ava:Ava_3181 0.0061 site-specific DNA-methyltransferase (cytosine-specific) K00590; COG: NOG05963 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.	0.803
EDM50381.1	EDM52503.1	EUBVEN_02332	EUBVEN_00259	KEGG: ava:Ava_0744 1.9e-06 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	RNA polymerase sigma-K factor; KEGG: reh:H16_A1626 2.5e-11 rpoD1; DNA-directed RNA polymerase sigma subunit (RpoD) K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the sigma-70 factor family.	0.805
EDM50381.1	gpr	EUBVEN_02332	EUBVEN_00229	KEGG: ava:Ava_0744 1.9e-06 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.	0.771
EDM50381.1	spoIIAB	EUBVEN_02332	EUBVEN_02333	KEGG: ava:Ava_0744 1.9e-06 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.999
EDM50381.1	spoIIP	EUBVEN_02332	EUBVEN_00230	KEGG: ava:Ava_0744 1.9e-06 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	Stage II sporulation protein P; KEGG: wbr:WGLp018 0.042 surA; parvulin-like peptidyl-prolyl isomerase K03771; COG: NOG13213 non supervised orthologous group.	0.813
EDM50381.1	spoIVB	EUBVEN_02332	EUBVEN_01350	KEGG: ava:Ava_0744 1.9e-06 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	SpoIVB peptidase; KEGG: btl:BALH_3781 4.6e-56 spoIVB; stage IV sporulation protein B; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1.	0.773
EDM50381.1	spoVAC	EUBVEN_02332	EUBVEN_02339	KEGG: ava:Ava_0744 1.9e-06 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	Stage V sporulation protein AC; KEGG: mbu:Mbur_1239 0.24 H+-transporting two-sector ATPase, C subunit K02124; COG: NOG09745 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 7.63.	0.871
EDM50381.1	spoVAD	EUBVEN_02332	EUBVEN_02350	KEGG: ava:Ava_0744 1.9e-06 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	Stage V sporulation protein AD; KEGG: cca:CCA00484 0.011 fabH; 3-oxoacyl-(acyl-carrier-protein) synthase III K00648; COG: NOG06312 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 7.63.	0.825
EDM50381.1	spoVAE	EUBVEN_02332	EUBVEN_02351	KEGG: ava:Ava_0744 1.9e-06 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	Stage V sporulation protein AE; KEGG: tfu:Tfu_2682 0.37 proton-translocating NADH-quinone oxidoreductase, chain N K00343; COG: NOG13202 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.	0.821
EDM50383.1	EDM50381.1	EUBVEN_02334	EUBVEN_02332	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; KEGG: hpa:HPAG1_0089 2.1e-16 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.	KEGG: ava:Ava_0744 1.9e-06 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	0.936
EDM50383.1	EDM51440.1	EUBVEN_02334	EUBVEN_01348	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; KEGG: hpa:HPAG1_0089 2.1e-16 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.	Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	0.646
EDM50383.1	EDM52118.1	EUBVEN_02334	EUBVEN_00646	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; KEGG: hpa:HPAG1_0089 2.1e-16 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.	Hypothetical protein; KEGG: ava:Ava_3181 0.0061 site-specific DNA-methyltransferase (cytosine-specific) K00590; COG: NOG05963 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.	0.583
EDM50383.1	gpr	EUBVEN_02334	EUBVEN_00229	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; KEGG: hpa:HPAG1_0089 2.1e-16 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.	GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.	0.620
EDM50383.1	spoIIAB	EUBVEN_02334	EUBVEN_02333	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; KEGG: hpa:HPAG1_0089 2.1e-16 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.	Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.953
EDM50383.1	spoIIP	EUBVEN_02334	EUBVEN_00230	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; KEGG: hpa:HPAG1_0089 2.1e-16 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.	Stage II sporulation protein P; KEGG: wbr:WGLp018 0.042 surA; parvulin-like peptidyl-prolyl isomerase K03771; COG: NOG13213 non supervised orthologous group.	0.434
EDM50383.1	spoIVB	EUBVEN_02334	EUBVEN_01350	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; KEGG: hpa:HPAG1_0089 2.1e-16 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.	SpoIVB peptidase; KEGG: btl:BALH_3781 4.6e-56 spoIVB; stage IV sporulation protein B; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1.	0.696
EDM50383.1	spoVAC	EUBVEN_02334	EUBVEN_02339	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; KEGG: hpa:HPAG1_0089 2.1e-16 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.	Stage V sporulation protein AC; KEGG: mbu:Mbur_1239 0.24 H+-transporting two-sector ATPase, C subunit K02124; COG: NOG09745 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 7.63.	0.773
EDM50383.1	spoVAD	EUBVEN_02334	EUBVEN_02350	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; KEGG: hpa:HPAG1_0089 2.1e-16 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.	Stage V sporulation protein AD; KEGG: cca:CCA00484 0.011 fabH; 3-oxoacyl-(acyl-carrier-protein) synthase III K00648; COG: NOG06312 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 7.63.	0.660