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| | prmA | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (319 aa) |
| | rsmE | RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (245 aa) |
| | EDS08716.1 | O-methyltransferase; KEGG: ctc:CTC01062 2.4e-43 caffeoyl-coA O-methyltransferase K00588; COG: COG4122 Predicted O-methyltransferase; Psort location: Cytoplasmic, score: 8.87. (214 aa) |
| | yhdJ_4 | KEGG: yps:YPTB1797 1.5e-64 putative DNA methyltransferase K07319; COG: COG0863 DNA modification methylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the N(4)/N(6)-methyltransferase family. (293 aa) |
| | ubiE | Methyltransferase domain protein; KEGG: bce:BC0620 5.7e-10 ubiquinone/menaquinone biosynthesis methyltransferase UbiE K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87. (255 aa) |
| | EDS08800.1 | Hypothetical protein. (61 aa) |
| | zntR_2 | Methyltransferase domain protein; KEGG: btk:BT9727_3407 3.2e-14 possible ubiquinone/menaquinone methyltransferase K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87. (393 aa) |
| | EDS08628.1 | Hypothetical protein; KEGG: spb:M28_Spy1090 1.7e-28 tRNA (uracil-5-)-methyltransferase K00599; COG: COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Psort location: Cytoplasmic, score: 8.87. (123 aa) |
| | yhdJ_3 | DNA (cytosine-5-)-methyltransferase; KEGG: spa:M6_Spy1144 5.6e-106 adenine-specific methyltransferase K00571; COG: COG1475 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87. (417 aa) |
| | YhdJ_1 | DNA (cytosine-5-)-methyltransferase; KEGG: hit:NTHI1495 2.1e-76 modification methylase DpnIIB-like K00571; COG: COG0863 DNA modification methylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the N(4)/N(6)-methyltransferase family. (281 aa) |
| | DpnM_1 | D12 class N6 adenine-specific DNA methyltransferase; KEGG: bbr:BB3607 1.2e-23 modification methylase K06223; COG: COG0338 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87. (275 aa) |
| | rrmJ | KEGG: cff:CFF8240_1111 1.0e-26 rrmJ; ribosomal RNA large subunit methyltransferase J K00599; COG: COG1189 Predicted rRNA methylase; Psort location: Cytoplasmic, score: 8.87. (269 aa) |
| | EDS08127.1 | Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: ctc:CTC01807 5.0e-27 putative 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: NOG21937 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (215 aa) |
| | metH_3 | KEGG: ctc:CTC01806 1.4e-203 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: COG1410 Methionine synthase I, cobalamin-binding domain; Psort location: Cytoplasmic, score: 8.87. (795 aa) |
| | rsmD | RNA methyltransferase, RsmD family; KEGG: fnu:FN1329 8.7e-30 methyltransferase K00599; COG: COG0742 N6-adenine-specific methylase; Psort location: Cytoplasmic, score: 8.87. (189 aa) |
| | RsmF | NOL1/NOP2/sun family protein; KEGG: lsl:LSL_0999 8.9e-76 putative 23S rRNA m(5)C methyltransferase K00599; COG: COG3270 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87. (479 aa) |
| | EDS08151.1 | Putative radical SAM protein YgiQ; KEGG: fnu:FN0734 4.3e-131 Fe-S oxidoreductase; COG: COG1032 Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87. (626 aa) |
| | EDS08164.1 | Radical SAM domain protein; KEGG: ctc:CTC02064 5.7e-177 Fe-S oxidoreductase; COG: COG1032 Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87. (621 aa) |
| | EDS08256.1 | DNA N-6-adenine-methyltransferase (Dam); KEGG: sac:SACOL0346 1.1e-40 prophage L54a, N-6-adenine-methyltransferase K00571; COG: NOG18143 non supervised orthologous group. (191 aa) |
| | Dam | D12 class N6 adenine-specific DNA methyltransferase; KEGG: bbr:BB3607 8.9e-21 modification methylase K06223; COG: COG0338 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87. (265 aa) |
| | dcm | DNA (cytosine-5-)-methyltransferase; KEGG: san:gbs1370 1.3e-37 similar to methyl transferase K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (418 aa) |
| | rlmH | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (159 aa) |
| | trmK | Hypothetical protein; KEGG: fnu:FN0907 0.0071 ribosomal RNA small subunit methyltransferase C K00564; COG: COG2384 Predicted SAM-dependent methyltransferase; Psort location: Cytoplasmic, score: 8.87. (232 aa) |
| | thyX | Hypothetical protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (257 aa) |
| | EDS07923.1 | Hypothetical protein; KEGG: fnu:FN0984 8.0e-36 tetracenomycin polyketide synthesis O-methyltransferase TcmP K00599; COG: COG3315 O-Methyltransferase involved in polyketide biosynthesis; Psort location: Cytoplasmic, score: 8.87. (281 aa) |
| | EDS07947.1 | Putative RNA methyltransferase, TrmH family, group 3; KEGG: gka:GK2709 6.1e-38 rRNA methylase K03437; COG: COG0566 rRNA methylases; Psort location: Cytoplasmic, score: 8.87. (263 aa) |
| | trmL | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (163 aa) |
| | hemN_1 | Radical SAM domain protein; KEGG: cpe:CPE1645 2.5e-112 Mg-protoporphyrin IX monomethyl ester oxidative cyclase K04034; COG: COG1032 Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87. (588 aa) |
| | EDS08022.1 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. (234 aa) |
| | trmB | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (233 aa) |
| | mraW | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (311 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (282 aa) |
| | DesVI | Methyltransferase domain protein; KEGG: bce:BC4326 3.0e-45 methyltransferase K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87. (264 aa) |
| | EDS07753.1 | RNA methyltransferase, TrmH family, group 3; KEGG: bce:BC0112 3.0e-68 23S rRNA methyltransferase K03218; COG: COG0566 rRNA methylases; Psort location: Cytoplasmic, score: 8.87; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (250 aa) |
| | trmD | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (244 aa) |
| | EDS07368.1 | MT-A70; KEGG: spj:MGAS2096_Spy1128 2.2e-56 adenine-specific methyltransferase K00571; COG: COG4725 Transcriptional activator, adenine-specific DNA methyltransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the MT-A70-like family. (187 aa) |
| | dcm-2 | KEGG: cac:CAC1222 4.8e-100 DNA-methyltransferase (cytosine-specific) K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87. (324 aa) |
| | EDS07056.1 | Putative rRNA methylase; KEGG: btl:BALH_4325 9.3e-26 mraW; SAM-dependent methyltransferase, MraW methylase family K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87. (187 aa) |
| | prmC | protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (283 aa) |
| | EDS07087.1 | Hypothetical protein; COG: COG3872 Predicted metal-dependent enzyme; Psort location: CytoplasmicMembrane, score: 9.97. (311 aa) |
| | gidB | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (237 aa) |
| | comC | Bacterial peptidase A24, N-terminal domain protein; KEGG: tte:TTE1266 3.5e-42 pppA; leader peptidase (prepilin peptidase) / N-methyltransferase K02654; COG: COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; Psort location: CytoplasmicMembrane, score: 10.00. (257 aa) |
| | RlmL | Hypothetical protein; KEGG: bcz:BCZK1441 1.3e-104 methyltransferase K00599; COG: COG0116 Predicted N6-adenine-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87. (390 aa) |
| | mboIIM_1 | Putative DNA (cytosine-5-)-methyltransferase; KEGG: lic:LIC11323 5.2e-10 methyltransferase DNA modification enzyme K00571; COG: COG0863 DNA modification methylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the N(4)/N(6)-methyltransferase family. (271 aa) |
| | dam | KEGG: mta:Moth_1737 2.2e-63 DNA adenine methylase K06223; COG: COG0338 Site-specific DNA methylase. (639 aa) |
| | MboIIM_2 | DNA (cytosine-5-)-methyltransferase; KEGG: spj:MGAS2096_Spy1124 6.6e-112 adenine-specific methyltransferase K00571; COG: COG0863 DNA modification methylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the N(4)/N(6)-methyltransferase family. (250 aa) |
| | menG | Methyltransferase domain protein; KEGG: sru:SRU_1592 2.7e-19 menaquinone biosynthesis methyltransferase UbiE K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87. (202 aa) |
| | EDS06243.1 | Restriction endonuclease; COG: NOG37482 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (783 aa) |
| | fokIM | KEGG: hhe:HH1050 1.4e-14 putative site-specific DNA-methyltransferase K07318; COG: COG3392 Adenine-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87. (957 aa) |
| | yfiC | Methyltransferase domain protein; KEGG: ctc:CTC00225 2.9e-54 methyltransferase K00599; COG: COG4123 Predicted O-methyltransferase; Psort location: Cytoplasmic, score: 8.87. (246 aa) |
| | rsmI | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (278 aa) |
| | EDS06121.1 | Methyltransferase domain protein; KEGG: plt:Plut_1697 1.2e-11 ubiquinone/menaquinone biosynthesis methyltransferase K03183; COG: COG0500 SAM-dependent methyltransferases. (201 aa) |
| | sun | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (436 aa) |
| | rlmN | 23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (357 aa) |
| | rumA | 23S rRNA (uracil-5-)-methyltransferase RumA; KEGG: ctc:CTC01941 1.1e-120 tRNA (uracil-5-) -methyltransferase K00557; COG: COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (460 aa) |
| | trmO | Methyltransferase, YaeB family; KEGG: eci:UTI89_C0211 9.6e-40 yaeB; hypothetical protein YaeB; COG: COG1720 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87. (236 aa) |
| | ksgA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (291 aa) |
| | EDS05781.1 | Putative FeS-containing Cyanobacterial-specific oxidoreductase; COG: COG1625 Fe-S oxidoreductase, related to NifB/MoaA family; Psort location: Cytoplasmic, score: 8.87. (476 aa) |
| | Ogt | 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (182 aa) |
| | rumA-2 | 23S rRNA (uracil-5-)-methyltransferase RumA; KEGG: bha:BH0687 1.9e-121 RNA methyltransferase K00599; COG: COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (567 aa) |
| | EDS05572.1 | Hypothetical protein. (71 aa) |
| | yhdJ_2 | KEGG: sth:STH334 7.3e-65 DNA modification methylase M.SthI K07319; COG: COG0863 DNA modification methylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the N(4)/N(6)-methyltransferase family. (319 aa) |
| | rlmN-2 | 23S rRNA m2A2503 methyltransferase; KEGG: fnu:FN0127 0.0038 Fe-S oxidoreductase; COG: COG0820 Predicted Fe-S-cluster redox enzyme; Psort location: Cytoplasmic, score: 8.87; Belongs to the radical SAM superfamily. RlmN family. (329 aa) |
| | EDS05616.1 | N-6 DNA Methylase; KEGG: chu:CHU_1468 6.8e-12 dpn; possible adenine-specific DNA methylase K00599; COG: COG4646 DNA methylase; Psort location: Cytoplasmic, score: 8.87. (2488 aa) |
| | EDS05635.1 | N-6 DNA Methylase; KEGG: dde:Dde_2498 1.6e-94 type I restriction-modification system, M subunit K03427; COG: COG0286 Type I restriction-modification system methyltransferase subunit; Psort location: Cytoplasmic, score: 8.87. (304 aa) |
| | EDS05636.1 | Hypothetical protein; KEGG: ana:alr3475 6.3e-43 type I restriction modification enzyme M subunit K03427; COG: COG0286 Type I restriction-modification system methyltransferase subunit. (131 aa) |
| | dinJ | Addiction module antitoxin, RelB/DinJ family; COG: COG3077 DNA-damage-inducible protein J. (101 aa) |
| | dnrC | Methyltransferase domain protein; KEGG: hsa:57412 1.3e-65 AS3MT; arsenic (+3 oxidation state) methyltransferase K07755; COG: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; Psort location: Cytoplasmic, score: 8.87. (423 aa) |
| | EDS05418.1 | Hypothetical protein; COG: COG0727 Predicted Fe-S-cluster oxidoreductase; Psort location: Cytoplasmic, score: 8.87. (229 aa) |
| | hpaIIM | Modification methylase HpaII; KEGG: mpe:MYPE9800 3.9e-75 cytosine-specific DNA methylase K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87. (405 aa) |
| | fliU | Hypothetical protein; KEGG: sec:SC1961 1.6e-10 fliB; N-methylation of lysine residues in flagellin K00599; COG: NOG18602 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (401 aa) |
| | hsdM | KEGG: tde:TDE0369 2.0e-245 hsdM-1; type I restriction-modification system, M subunit K03427; COG: COG0286 Type I restriction-modification system methyltransferase subunit; Psort location: Cytoplasmic, score: 8.87. (890 aa) |
| | cbiD | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (384 aa) |
| | cobI | KEGG: mst:Msp_0038 1.4e-31 cbiL; CbiL K03394; COG: COG2243 Precorrin-2 methylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the precorrin methyltransferase family. (231 aa) |
| | cobM | KEGG: mta:Moth_1092 1.4e-68 precorrin-4 C11-methyltransferase K03396; COG: COG2875 Precorrin-4 methylase. (264 aa) |
| | cbiG | CbiG; KEGG: dde:Dde_3181 1.8e-33 precorrin-3B C17-methyltransferase K02189:K03395:K00594; COG: COG2073 Cobalamin biosynthesis protein CbiG; Psort location: Cytoplasmic, score: 8.87. (348 aa) |
| | cobJ | KEGG: lmo:lmo1199 7.6e-63 cbiH; precorrin-3B C17-methyltransferase K03395; COG: COG1010 Precorrin-3B methylase; Psort location: Cytoplasmic, score: 8.87. (245 aa) |
| | cobK | precorrin-6A reductase; KEGG: ctc:CTC00734 5.1e-57 cbiT; precorrin-6B methylase/decarboxylase cbiT/cbiE K03399:K02191; COG: COG2241 Precorrin-6B methylase 1; Psort location: Cytoplasmic, score: 8.87. (664 aa) |
| | hemC | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (803 aa) |
| | EDS05153.1 | Hypothetical protein; COG: COG5441 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87. (416 aa) |
| | EDS05245.1 | Hypothetical protein; KEGG: bbr:BB1668 1.4e-16 modification methylase K00558; COG: COG0270 Site-specific DNA methylase. (93 aa) |
| | EDS05270.1 | COG: COG4422 Bacteriophage protein gp37. (235 aa) |
| | EDS05280.1 | Hypothetical protein. (46 aa) |
| | rlmK | Hypothetical protein; KEGG: zmo:ZMO1889 7.7e-54 SAM-dependent methyltransferase K00568; COG: COG1092 Predicted SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87. (286 aa) |
