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EFB76659.1 EFB76659.1 EFB75245.1 EFB75245.1 gap gap pfp-2 pfp-2 pfp pfp pgk pgk tpiA tpiA gpmI gpmI ptbA ptbA EFB76155.1 EFB76155.1 EFB76096.1 EFB76096.1 EFB76065.1 EFB76065.1 ppdK ppdK EFB75760.1 EFB75760.1 pyk pyk pgi pgi pfkA-2 pfkA-2 EFB76779.1 EFB76779.1 tpiA-2 tpiA-2 pfkA pfkA EFB76538.1 EFB76538.1 EFB76475.1 EFB76475.1 EFB76853.1 EFB76853.1 EFB77002.1 EFB77002.1 fba fba EFB74345.1 EFB74345.1 EFB74343.1 EFB74343.1 EFB74407.1 EFB74407.1 EFB74399.1 EFB74399.1 fbp fbp EFB74583.1 EFB74583.1 pckA pckA nifJ nifJ EFB74795.1 EFB74795.1 EFB74849.1 EFB74849.1 EFB74848.1 EFB74848.1 EFB74832.1 EFB74832.1 EFB74980.1 EFB74980.1 EFB74938.1 EFB74938.1 EFB74995.1 EFB74995.1 EFB75166.1 EFB75166.1 EFB75285.1 EFB75285.1 pfp-3 pfp-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EFB76659.1ROK family protein; KEGG: tte:TTE1961 1.7e-56 nagC4; transcriptional regulator K00845; Psort location: Cytoplasmic, score: 9.97. (318 aa)
EFB75245.1Ketose-bisphosphate aldolase; KEGG: cte:CT1053 1.6e-56 fbaA; fructose-bisphosphate aldolase, class II K01624; Psort location: Cytoplasmic, score: 8.96. (384 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: nma:NMA0246 4.8e-116 glyceraldehyde 3-phosphate dehydrogenase C K00134; Psort location: Cytoplasmic, score: 9.97; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (342 aa)
pfp-2Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (411 aa)
pfpPhosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (407 aa)
pgkPhosphoglycerate kinase; KEGG: cno:NT01CX_1411 8.9e-140 phosphoglycerate kinase K00927; Psort location: Cytoplasmic, score: 9.26. (402 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (256 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (508 aa)
ptbAKEGG: efa:EF2598 1.1e-32 PTS system, beta-glucoside-specific IIABC component K02755:K02756:K02757; Psort location: CytoplasmicMembrane, score: 9.82. (170 aa)
EFB76155.1Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (349 aa)
EFB76096.1KEGG: cpf:CPF_1070 7.2e-138 PTS system, N-acetylglucosamine-specific IIBC component K02803:K02804; Psort location: CytoplasmicMembrane, score: 10.00. (491 aa)
EFB76065.1Phage prohead protease, HK97 family. (209 aa)
ppdKPyruvate, phosphate dikinase; KEGG: tte:TTE0981 0. ppsA2; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01006; Psort location: Cytoplasmic, score: 9.97; Belongs to the PEP-utilizing enzyme family. (891 aa)
EFB75760.1Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: cpr:CPR_1841 1.6e-131 phosphomannomutase K01840. (560 aa)
pykPyruvate kinase; KEGG: tte:TTE1815 6.5e-160 pykF; pyruvate kinase K00873; Belongs to the pyruvate kinase family. (581 aa)
pgiKEGG: gka:GK2924 1.0e-136 glucose-6-phosphate isomerase K01810; Psort location: Cytoplasmic, score: 9.26; Belongs to the GPI family. (444 aa)
pfkA-2Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (358 aa)
EFB76779.1S1 RNA binding domain protein; KEGG: saa:SAUSA300_0486 8.4e-25 polyribonucleotide nucleotidyltransferase K00962; Psort location: Cytoplasmic, score: 9.26. (154 aa)
tpiA-2KEGG: mag:amb1819 6.1e-22 triosephosphate isomerase K01803; Psort location: Cytoplasmic, score: 8.96. (281 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (324 aa)
EFB76538.1HAD hydrolase, family IA, variant 3; KEGG: ret:RHE_CH00996 7.9e-13 probable hydrolase protein K01560; Psort location: Cytoplasmic, score: 8.96. (203 aa)
EFB76475.1GroES-like protein; KEGG: lsa:LSA0966 4.3e-92 putative zinc-containing alcohol dehydrogenase (oxidoreductase). (333 aa)
EFB76853.1Glycosyl hydrolase, family 1; KEGG: pho:PH0366 6.0e-54 423aa long hypothetical beta-glucosidase K01188; Psort location: Cytoplasmic, score: 9.26; Belongs to the glycosyl hydrolase 1 family. (446 aa)
EFB77002.1Aldose 1-epimerase; KEGG: ldb:Ldb1268 1.8e-45 putative mutarotase K01785; Psort location: Cytoplasmic, score: 8.96. (293 aa)
fbaKEGG: cpr:CPR_1350 1.2e-112 fba; fructose-1,6-bisphosphate aldolase, class II K01624. (287 aa)
EFB74345.1KEGG: sdy:SDY_4132 8.8e-53 putative aldolase K01624. (276 aa)
EFB74343.1ROK family protein; KEGG: eci:UTI89_C0670 2.2e-24 nagC; transcriptional repressor of nag (N-acetylglucosamine) operon K02565; Psort location: Cytoplasmic, score: 9.97. (376 aa)
EFB74407.1PTS system, glucose-like IIB component; KEGG: gka:GK0991 1.0e-153 PTS system, glucose-specific enzyme II, A component K02763:K02764:K02765; Psort location: CytoplasmicMembrane, score: 10.00. (709 aa)
EFB74399.1KEGG: bma:BMA2132 8.8e-21 glucokinase/transcriptional regulator, RpiR family, fusion K00845. (282 aa)
fbpKEGG: cno:NT01CX_1512 1.8e-173 fructose-1,6-bisphosphatase K01086; Psort location: Cytoplasmic, score: 8.96. (656 aa)
EFB74583.1Hypothetical protein; KEGG: ctc:CTC01741 1.0e-113 pyruvate-flavodoxin oxidoreductase K03737. (386 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
nifJPyruvate synthase; KEGG: ctc:CTC01741 3.5e-296 pyruvate-flavodoxin oxidoreductase K03737. (909 aa)
EFB74795.1Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: bcl:ABC1499 1.2e-119 phosphomannomutase K01835:K01840; Psort location: Cytoplasmic, score: 8.96. (557 aa)
EFB74849.1Transcriptional regulator, RpiR family. (268 aa)
EFB74848.1KEGG: efa:EF0272 8.3e-128 glycosyl hydrolase, family 1 K01223; Psort location: Cytoplasmic, score: 9.26. (492 aa)
EFB74832.1SIS domain protein; KEGG: mka:MK1663 3.1e-05 predicted sugar phosphate isomerase K08094. (258 aa)
EFB74980.1Transcriptional regulator, RpiR family. (261 aa)
EFB74938.1ROK family protein; KEGG: cjk:jk0728 1.4e-18 glk; glucokinase K00845; Psort location: Cytoplasmic, score: 9.26. (433 aa)
EFB74995.1KEGG: bte:BTH_I1550 9.4e-09 glucokinase/transcriptional regulator, RpiR family, fusion K00845. (278 aa)
EFB75166.1Hypothetical protein. (183 aa)
EFB75285.1Aldose 1-epimerase; KEGG: rha:RHA1_ro04996 1.1e-10 aldose 1-epimerase K01785. (345 aa)
pfp-3Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (389 aa)
Your Current Organism:
Subdoligranulum variabile
NCBI taxonomy Id: 411471
Other names: S. variabile DSM 15176, Subdoligranulum variabile DSM 15176
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