STRINGSTRING
purM purM purN purN EEU97002.1 EEU97002.1 EEU97003.1 EEU97003.1 purD purD EEU97006.1 EEU97006.1 purB purB dut dut EEU96983.1 EEU96983.1 EEU96888.1 EEU96888.1 EEU96890.1 EEU96890.1 EEU96853.1 EEU96853.1 gmk gmk priA priA coaD coaD coaE coaE EEU96742.1 EEU96742.1 pncB pncB EEU96751.1 EEU96751.1 nadD nadD EEU96783.1 EEU96783.1 cinA cinA atpC-2 atpC-2 atpD-2 atpD-2 atpG-2 atpG-2 atpA-2 atpA-2 atpF-2 atpF-2 atpE-2 atpE-2 atpB-2 atpB-2 adk adk EEU96596.1 EEU96596.1 nusA nusA ribF ribF rpoA rpoA nrdG nrdG EEU95750.1 EEU95750.1 udk udk ackA ackA pyrG-2 pyrG-2 EEU95926.1 EEU95926.1 EEU95912.1 EEU95912.1 EEU95012.1 EEU95012.1 pyrI pyrI EEU95949.1 EEU95949.1 EEU95961.1 EEU95961.1 EEU95958.1 EEU95958.1 EEU95957.1 EEU95957.1 EEU95986.1 EEU95986.1 tgt tgt queA queA EEU96054.1 EEU96054.1 EEU96093.1 EEU96093.1 EEU96107.1 EEU96107.1 EEU96132.1 EEU96132.1 EEU96123.1 EEU96123.1 pyrH pyrH polC polC EEU96297.1 EEU96297.1 EEU96338.1 EEU96338.1 EEU96324.1 EEU96324.1 EEU96311.1 EEU96311.1 nusB nusB EEU96408.1 EEU96408.1 EEU95115.1 EEU95115.1 EEU94891.1 EEU94891.1 EEU96466.1 EEU96466.1 EEU96476.1 EEU96476.1 dacA dacA EEU96555.1 EEU96555.1 EEU96559.1 EEU96559.1 pyrG pyrG EEU96373.1 EEU96373.1 EEU96374.1 EEU96374.1 EEU96375.1 EEU96375.1 EEU96378.1 EEU96378.1 holA holA EEU97637.1 EEU97637.1 atpB atpB atpE atpE atpF atpF atpH atpH atpA atpA EEU97654.1 EEU97654.1 atpG atpG atpD atpD atpC atpC sigA sigA EEU97748.1 EEU97748.1 EEU97998.1 EEU97998.1 EEU97965.1 EEU97965.1 dinB dinB EEU97941.1 EEU97941.1 EEU97933.1 EEU97933.1 EEU97893.1 EEU97893.1 purC purC EEU97823.1 EEU97823.1 EEU97787.1 EEU97787.1 cmk cmk EEU98016.1 EEU98016.1 pyrF pyrF EEU98013.1 EEU98013.1 pyrD pyrD pyrE pyrE carA carA carB carB coaX coaX serS serS dnaN-2 dnaN-2 dnaN dnaN EEU98303.1 EEU98303.1 EEU98275.1 EEU98275.1 EEU98274.1 EEU98274.1 EEU98251.1 EEU98251.1 EEU98161.1 EEU98161.1 EEU98139.1 EEU98139.1 EEU98098.1 EEU98098.1 EEU95244.1 EEU95244.1 xpt xpt murAA murAA EEU95209.1 EEU95209.1 EEU95197.1 EEU95197.1 accA accA sigF sigF rfbD rfbD prs prs murA murA thyX thyX accD accD queH queH purA purA rfbC rfbC EEU95492.1 EEU95492.1 EEU95616.1 EEU95616.1 tdk tdk EEU95029.1 EEU95029.1 EEU95022.1 EEU95022.1 guaA guaA rpoC rpoC rpoB rpoB EEU97615.1 EEU97615.1 rpoD rpoD dnaG dnaG EEU97561.1 EEU97561.1 EEU97520.1 EEU97520.1 EEU97456.1 EEU97456.1 EEU97490.1 EEU97490.1 nadE nadE polA polA nusG nusG EEU97383.1 EEU97383.1 upp upp dnaX dnaX coaX-2 coaX-2 coaBC coaBC hpt hpt dnaB dnaB folD folD EEU97037.1 EEU97037.1 EEU97038.1 EEU97038.1 purE purE purF purF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
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textmining
co-expression
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purMPhosphoribosylformylglycinamidine cyclo-ligase; KEGG: bcl:ABC1032 6.9e-101 purM; phosphoribosylaminoimidazole synthetase K01933; Psort location: Cytoplasmic, score: 8.96. (348 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (198 aa)
EEU97002.1IMP cyclohydrolase-like protein; KEGG: mst:Msp_1398 3.0e-07 purO; PurO K01492; Psort location: Cytoplasmic, score: 8.96. (273 aa)
EEU97003.1AICARFT/IMPCHase bienzyme; KEGG: sce:YMR120C 5.5e-115 ADE17; AICAR transformylase/IMP cyclohydrolase K00602:K01492. (393 aa)
purDKEGG: sth:STH2849 6.8e-110 phosphoribosylamine--glycine ligase K01945; Belongs to the GARS family. (433 aa)
EEU97006.1KEGG: blo:BL1108 2.4e-256 purL; phosphoribosylformylglycinamidine synthase K01952; overlaps another CDS with the same product name. (761 aa)
purBAdenylosuccinate lyase; KEGG: cpf:CPF_1922 3.7e-157 purB; adenylosuccinate lyase K01756; Psort location: Cytoplasmic, score: 8.96. (462 aa)
dutdUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (152 aa)
EEU96983.1Sigma-70 region 2; KEGG: reh:H16_A2373 3.7e-11 rpoS; DNA-directed RNA polymerase sigma subunit (sigma38) K00960; Psort location: Cytoplasmic, score: 9.97; Belongs to the sigma-70 factor family. (153 aa)
EEU96888.1Sigma-70, region 4; Psort location: Cytoplasmic, score: 8.96. (166 aa)
EEU96890.1Sigma-70 region 2; KEGG: shn:Shewana3_0763 1.7e-10 RNA polymerase, sigma-24 subunit, ECF subfamily K00058; Belongs to the sigma-70 factor family. ECF subfamily. (170 aa)
EEU96853.1Carboxyl transferase domain protein; KEGG: sto:ST0591 3.2e-48 methylmalonyl-CoA decarboxylase alpha chain K01604. (439 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (190 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (728 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (167 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (209 aa)
EEU96742.1Putative inosine-5'-monophosphate dehydrogenase; KEGG: lmo:lmo0132 6.5e-208 similar to inosine monophosphate dehydrogenase K00088. (504 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (505 aa)
EEU96751.1Hypothetical protein. (119 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (228 aa)
EEU96783.1Hydrolase, HD family; KEGG: mmy:MSC_0442 1.8e-22 probable nicotinate-nucleotide adenylyltransferase K00969; Psort location: Cytoplasmic, score: 8.96. (195 aa)
cinACompetence/damage-inducible domain protein CinA; KEGG: hsa:80308 2.3e-11 FLAD1; FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae) K00953; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. (439 aa)
atpC-2KEGG: bcl:ABC3850 1.2e-14 atpC; F0F1-type ATP synthase epsilon chain K02114. (116 aa)
atpD-2ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (470 aa)
atpG-2ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (292 aa)
atpA-2ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (584 aa)
atpF-2ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (163 aa)
atpE-2ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (74 aa)
atpB-2ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (227 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (210 aa)
EEU96596.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (58 aa)
nusATranscription termination factor NusA; Participates in both transcription termination and antitermination. (358 aa)
ribFRiboflavin biosynthesis protein RibF; KEGG: bba:Bd1507 2.1e-42 ribC; riboflavin kinase / FAD synthase ribC K00861:K00953; Psort location: Cytoplasmic, score: 8.96; Belongs to the ribF family. (306 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (332 aa)
nrdGAnaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (183 aa)
EEU95750.1ImpB/MucB/SamB family protein; KEGG: btl:BALH_p0040 5.8e-33 uvrX; DNA-damage repair protein (DNA polymerase IV) K00961; Psort location: Cytoplasmic, score: 8.96. (502 aa)
udkUridine kinase; KEGG: sth:STH1046 7.8e-61 uridine kinase K00876; Psort location: Cytoplasmic, score: 8.96. (209 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
pyrG-2CTP synthase; KEGG: chy:CHY_0125 7.2e-35 pyrG; CTP synthetase K01937. (81 aa)
EEU95926.1Sigma-70, region 4; KEGG: reh:H16_B1727 3.4e-12 prtI; DNA-directed RNA polymerase sigma subunit PrtI (ECF sigma factor) K00960; Psort location: Cytoplasmic, score: 8.96; Belongs to the sigma-70 factor family. ECF subfamily. (157 aa)
EEU95912.1Sigma-70 region 2; KEGG: reh:H16_A2563 0.00031 rpoE1; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K00960; Psort location: Cytoplasmic, score: 8.96; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa)
EEU95012.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (967 aa)
pyrIAspartate carbamoyltransferase regulatory chain, allosteric domain protein; KEGG: blo:BL0793 1.1e-24 pyrI; aspartate carbamoyltransferase regulatory chain K00610; Psort location: Cytoplasmic, score: 8.96. (145 aa)
EEU95949.1Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain protein; KEGG: ctc:CTC02384 2.1e-42 aspartate carbamoyltransferase catalytic chain K00609; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (143 aa)
EEU95961.1NAD dependent epimerase/dehydratase family protein; KEGG: bha:BH3365 1.4e-20 rfbD; spore coat polysaccharide synthesis (dTDP-4-dehydrorhamnose reductase) K00067. (277 aa)
EEU95958.1Sigma-70, region 4. (76 aa)
EEU95957.1Sigma-70 region 2; KEGG: reh:H16_A2563 0.00011 rpoE1; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K00960; Belongs to the sigma-70 factor family. (84 aa)
EEU95986.1KEGG: tte:TTE1818 0. dnaE; DNA polymerase III alpha subunit K02337; Psort location: Cytoplasmic, score: 9.97. (1171 aa)
tgttRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (381 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (274 aa)
EEU96054.1Putative S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (121 aa)
EEU96093.1Hypothetical protein; KEGG: ppd:Ppro_1579 0.0015 NAD(+) kinase K00858. (67 aa)
EEU96107.1NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (210 aa)
EEU96132.1Sigma-70, region 4; Psort location: Cytoplasmic, score: 8.96. (118 aa)
EEU96123.1ImpB/MucB/SamB family protein; KEGG: btl:BALH_p0040 1.9e-43 uvrX; DNA-damage repair protein (DNA polymerase IV) K00961. (501 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (236 aa)
polCDNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1417 aa)
EEU96297.1Sigma-70, region 4; KEGG: bcz:BCZK3297 6.8e-07 RNA polymerase ECF-type sigma factor K03088; Psort location: Cytoplasmic, score: 8.96. (101 aa)
EEU96338.1CHC2 zinc finger domain protein; KEGG: dde:Dde_2053 3.0e-12 DNA primase K02316. (214 aa)
EEU96324.1KEGG: reh:H16_A2563 1.0e-10 rpoE1; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K00960; Psort location: Cytoplasmic, score: 8.96; Belongs to the sigma-70 factor family. ECF subfamily. (149 aa)
EEU96311.1RNA polymerase sigma factor, sigma-70 family; Psort location: Cytoplasmic, score: 8.96. (147 aa)
nusBTranscription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (147 aa)
EEU96408.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (133 aa)
EEU95115.1Hypothetical protein; KEGG: dde:Dde_2053 4.9e-05 DNA primase K02316; Psort location: Cytoplasmic, score: 8.96. (205 aa)
EEU94891.1Hypothetical protein. (54 aa)
EEU96466.1Exonuclease; KEGG: chy:CHY_1772 2.3e-14 polC; DNA polymerase III, alpha subunit, Gram-positive type K03763; Psort location: Cytoplasmic, score: 8.96. (244 aa)
EEU96476.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (179 aa)
dacATIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (300 aa)
EEU96555.1RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (767 aa)
EEU96559.1Phosphoribulokinase/uridine kinase family protein; KEGG: cac:CAC0672 1.8e-36 fision threonyl-tRNA synthetase (N-terminal part) and uridine kinase K00876; Psort location: Cytoplasmic, score: 8.96. (312 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (461 aa)
EEU96373.1RNA polymerase sigma factor, sigma-70 family; Psort location: Cytoplasmic, score: 8.96. (165 aa)
EEU96374.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (150 aa)
EEU96375.1Sigma-70, region 4; Psort location: Cytoplasmic, score: 8.96. (142 aa)
EEU96378.1RNA polymerase sigma factor, sigma-70 family; Psort location: Cytoplasmic, score: 8.96. (141 aa)
holAKEGG: bce:BC4321 8.0e-20 DNA polymerase III, delta subunit K02340; Psort location: Cytoplasmic, score: 8.96. (342 aa)
EEU97637.1Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0467 5.8e-72 glutamate synthase, small subunit K00226; Psort location: Cytoplasmic, score: 9.26. (341 aa)
atpBATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (247 aa)
atpEATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (93 aa)
atpFATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (168 aa)
atpHATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (179 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (506 aa)
EEU97654.1KEGG: rso:RSc3318 5.4e-12 atpG, RS02548; probable ATP synthase gamma chain protein K02115; overlaps another CDS with the same product name. (154 aa)
atpGKEGG: ppd:Ppro_1506 4.8e-29 ATP synthase F1, gamma subunit K01550; overlaps another CDS with the same product name. (187 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (464 aa)
atpCATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (132 aa)
sigAPutative RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (461 aa)
EEU97748.1Bacterial transferase hexapeptide repeat protein; KEGG: tte:TTE2572 4.3e-53 glmU; glucosamine-1-phosphate N-acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase K04042:K00972; Psort location: Cytoplasmic, score: 9.26. (251 aa)
EEU97998.1CHC2 zinc finger domain protein; KEGG: dvu:DVU1789 2.8e-06 dnaG; DNA primase K02316. (173 aa)
EEU97965.1RelA/SpoT domain protein; KEGG: bce:BC4341 2.0e-39 GTP pyrophosphokinase K00951; Psort location: Cytoplasmic, score: 8.96. (226 aa)
dinBImpB/MucB/SamB family protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (411 aa)
EEU97941.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (367 aa)
EEU97933.1Sigma-70 region 2; KEGG: reh:H16_A1096 1.1e-06 rpoE3; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K00960; Psort location: Cytoplasmic, score: 8.96; Belongs to the sigma-70 factor family. ECF subfamily. (161 aa)
EEU97893.1KEGG: plt:Plut_2048 4.7e-07 pyrE; orotate phosphoribosyltransferase K00762. (211 aa)
purCKEGG: cef:CE2487 4.0e-80 hemH; phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Belongs to the SAICAR synthetase family. (312 aa)
EEU97823.1Sigma-70 region 2; KEGG: reh:H16_A2373 2.2e-05 rpoS; DNA-directed RNA polymerase sigma subunit (sigma38) K00960; Belongs to the sigma-70 factor family. (221 aa)
EEU97787.1Sigma-70 region 2; KEGG: btl:BALH_3229 1.8e-13 sigW; RNA polymerase sigma-70 factor, ECF subfamily K00960; Psort location: Cytoplasmic, score: 8.96. (163 aa)
cmkCytidylate kinase; KEGG: pca:Pcar_1884 9.4e-49 cytidylate kinase K00945; Psort location: Cytoplasmic, score: 8.96. (221 aa)
EEU98016.1Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (396 aa)
pyrFKEGG: cpr:CPR_1199 3.7e-86 pyrF; orotidine 5'-phosphate decarboxylase K01591; Psort location: Cytoplasmic, score: 8.96; Belongs to the OMP decarboxylase family. Type 2 subfamily. (288 aa)
EEU98013.1Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0392 4.5e-49 dihydroorotate dehydrogenase electron transfer subunit K00226; Psort location: Cytoplasmic, score: 8.96. (257 aa)
pyrDDihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. (308 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (232 aa)
carAKEGG: lmf:LMOf2365_1864 1.9e-89 carA; carbamoyl-phosphate synthase, small subunit K01956; Psort location: Cytoplasmic, score: 8.96; Belongs to the CarA family. (369 aa)
carBKEGG: cpe:CPE2572 0. carB; carbamoyl-phosphate synthetase catalytic subunit K01955; Psort location: Cytoplasmic, score: 8.96. (1083 aa)
coaXPantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (258 aa)
serSserine--tRNA ligase; KEGG: mhu:Mhun_2507 2.3e-86 seryl-tRNA synthetase K01875; Psort location: Cytoplasmic, score: 10.00. (443 aa)
dnaN-2KEGG: cac:CAC0002 2.2e-26 dnaN; DNA polymerase III beta subunit K02338; Psort location: Cytoplasmic, score: 8.96; overlaps another CDS with the same product name. (173 aa)
dnaNKEGG: ctc:CTC00093 2.6e-37 DNA polymerase III, beta chain K02338; Psort location: Cytoplasmic, score: 8.96; overlaps another CDS with the same product name. (221 aa)
EEU98303.1KEGG: fal:FRAAL6581 3.6e-19 holB; DNA polymerase III delta' subunit K02341. (321 aa)
EEU98275.1Phage/plasmid primase, P4 family domain protein; KEGG: hwa:HQ4022A 6.8e-05 putative P4-specific DNA primase; Psort location: Cytoplasmic, score: 8.96. (448 aa)
EEU98274.1CHC2 zinc finger domain protein; KEGG: dvu:DVU1789 1.2e-09 dnaG; DNA primase K02316; Psort location: Cytoplasmic, score: 8.96. (151 aa)
EEU98251.1Hypothetical protein; KEGG: mka:MK0911 7.7e-06 carB_2; carbamoylphosphate synthase large subunit K01955. (457 aa)
EEU98161.1Sigma-70, region 4; KEGG: btl:BALH_3229 1.4e-06 sigW; RNA polymerase sigma-70 factor, ECF subfamily K00960; Psort location: Cytoplasmic, score: 8.96. (140 aa)
EEU98139.1Sigma-70 region 2; KEGG: chu:CHU_3562 4.3e-07 rpoE; RNA polymerase sigma-70 factor, ECF subfamily K00960; Psort location: Cytoplasmic, score: 8.96. (186 aa)
EEU98098.1Hypothetical protein; KEGG: sat:SYN_01231 7.0e-21 cytidylate kinase K00945; Psort location: Cytoplasmic, score: 8.96. (202 aa)
EEU95244.1Sigma-70 region 2; KEGG: reh:H16_A1096 3.3e-14 rpoE3; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K00960; Psort location: Cytoplasmic, score: 8.96; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (208 aa)
murAAKEGG: dvu:DVU3258 6.9e-37 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790; Psort location: Cytoplasmic, score: 8.96; overlaps another CDS with the same product name. (276 aa)
EEU95209.1KEGG: rpc:RPC_4418 4.1e-22 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790; Psort location: Cytoplasmic, score: 8.96; overlaps another CDS with the same product name. (233 aa)
EEU95197.1ACT domain protein; KEGG: nph:NP5006A 3.7e-10 purU; formyltetrahydrofolate deformylase K01433. (94 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
sigFKEGG: hpa:HPAG1_0089 1.9e-18 RNA polymerase sigma-80 factor K00960; Psort location: Cytoplasmic, score: 9.97; Belongs to the sigma-70 factor family. (222 aa)
rfbDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (306 aa)
prsKEGG: cpr:CPR_1519 1.2e-94 prs; ribose-phosphate pyrophosphokinase K00948; Belongs to the ribose-phosphate pyrophosphokinase family. (380 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (458 aa)
thyXThymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (259 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa)
queHHypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (206 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (438 aa)
rfbCdTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (188 aa)
EEU95492.1RNA polymerase sigma factor, sigma-70 family. (271 aa)
EEU95616.1Sigma-70 region 2; KEGG: reh:H16_A2563 7.9e-13 rpoE1; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K00960; Psort location: Cytoplasmic, score: 8.96; Belongs to the sigma-70 factor family. ECF subfamily. (176 aa)
tdkThymidine kinase; KEGG: cpr:CPR_2178 3.5e-58 tdk; thymidine kinase K00857; Psort location: Cytoplasmic, score: 8.96. (202 aa)
EEU95029.1dTMP kinase; KEGG: ctc:CTC00220 5.9e-56 thymidylate kinase K00943. (222 aa)
EEU95022.1RecF/RecN/SMC N-terminal domain protein; KEGG: plt:Plut_1242 0.0010 phosphate transport system permease protein 1 K02036; Psort location: Cytoplasmic, score: 8.96. (417 aa)
guaAGMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. (516 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1191 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (998 aa)
EEU97615.1KEGG: cno:NT01CX_1107 9.7e-89 rpoB; DNA-directed RNA polymerase, beta subunit K00960; Psort location: Cytoplasmic, score: 9.26; overlaps another CDS with the same product name. (292 aa)
rpoDRNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (359 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (591 aa)
EEU97561.1CHC2 zinc finger domain protein; KEGG: gbe:GbCGDNIH1_2285 7.1e-12 DNA primase. (88 aa)
EEU97520.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (125 aa)
EEU97456.1CHC2 zinc finger domain protein; KEGG: dde:Dde_2053 5.0e-12 DNA primase K02316. (212 aa)
EEU97490.1RNA polymerase sigma factor, sigma-70 family; Psort location: Cytoplasmic, score: 8.96. (162 aa)
nadENAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (644 aa)
polAKEGG: sth:STH848 2.4e-176 DNA polymerase I K02335. (859 aa)
nusGTranscription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. (176 aa)
EEU97383.1Putative uridine kinase; KEGG: ana:alr2350 2.1e-10 phosphoribulokinase K00855. (194 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (205 aa)
dnaXDNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (625 aa)
coaX-2Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (295 aa)
coaBCPhosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (398 aa)
hptKEGG: tte:TTE2394 1.5e-59 hpt; hypoxanthine-guanine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.26; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (181 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (467 aa)
folDTetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (281 aa)
EEU97037.1Putative RNA polymerase sigma-G factor; KEGG: reh:H16_A2373 2.0e-23 rpoS; DNA-directed RNA polymerase sigma subunit (sigma38) K00960; Psort location: Cytoplasmic, score: 9.97; Belongs to the sigma-70 factor family. (254 aa)
EEU97038.1KEGG: bcc:BCc_016 2.8e-14 rpoH; RNA polymerase sigma-32 factor K00960; Psort location: Cytoplasmic, score: 8.96; Belongs to the sigma-70 factor family. (188 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (166 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (464 aa)
Your Current Organism:
Faecalibacterium prausnitzii A2165
NCBI taxonomy Id: 411483
Other names: F. prausnitzii A2-165, Faecalibacterium prausnitzii A2-165
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