STRINGSTRING
EEU98346.1 EEU98346.1 aroK aroK EEU98233.1 EEU98233.1 argC argC galE galE EEU98057.1 EEU98057.1 EEU98059.1 EEU98059.1 ilvC ilvC pdxB pdxB EEU97764.1 EEU97764.1 trkA trkA EEU97299.1 EEU97299.1 gap gap EEU97400.1 EEU97400.1 EEU97410.1 EEU97410.1 EEU97420.1 EEU97420.1 EEU97173.1 EEU97173.1 gpsA gpsA EEU97152.1 EEU97152.1 folD folD pdxB-2 pdxB-2 EEU97000.1 EEU97000.1 proC proC EEU96802.1 EEU96802.1 EEU96820.1 EEU96820.1 LYS1 LYS1 EEU96231.1 EEU96231.1 dxr dxr EEU96221.1 EEU96221.1 EEU96207.1 EEU96207.1 EEU96165.1 EEU96165.1 EEU96109.1 EEU96109.1 dapB dapB asd asd EEU96065.1 EEU96065.1 EEU96066.1 EEU96066.1 EEU95983.1 EEU95983.1 EEU95961.1 EEU95961.1 EEU95716.1 EEU95716.1 rex rex cobK cobK EEU95425.1 EEU95425.1 fabG fabG EEU95187.1 EEU95187.1 EEU95188.1 EEU95188.1 EEU95238.1 EEU95238.1 EEU94944.1 EEU94944.1 rfbD rfbD rfbB rfbB EEU94907.1 EEU94907.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EEU98346.1KEGG: cno:NT01CX_0626 2.0e-48 prephenate dehydrogenase K00210; Psort location: Cytoplasmic, score: 8.96. (286 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (420 aa)
EEU98233.1Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: sph:MGAS10270_Spy1169 8.9e-92 fructuronate reductase K00040; Psort location: Cytoplasmic, score: 9.26; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (284 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (311 aa)
galEKEGG: bat:BAS5304 3.3e-117 UDP-glucose 4-epimerase K01784; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (362 aa)
EEU98057.1TrkA N-terminal domain protein; Psort location: Cytoplasmic, score: 8.96. (221 aa)
EEU98059.1TrkA N-terminal domain protein; Psort location: Cytoplasmic, score: 8.96. (137 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
pdxB4-phosphoerythronate dehydrogenase; KEGG: tbd:Tbd_0950 4.4e-99 D-isomer specific 2-hydroxyacid dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.26. (386 aa)
EEU97764.1Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: sth:STH968 1.2e-50 3-oxoacyl-(acyl-carrier protein) reductase K00059; Psort location: Cytoplasmic, score: 9.26. (295 aa)
trkAPotassium transporter peripheral membrane component; KEGG: tma:TM0754 0.00088 oxidoreductase; Psort location: Cytoplasmic, score: 8.96. (452 aa)
EEU97299.1NAD dependent epimerase/dehydratase family protein; KEGG: sat:SYN_02668 2.3e-15 UDP-glucose 4-epimerase K01784; Psort location: Cytoplasmic, score: 8.96. (334 aa)
gapKEGG: fth:FTH_1121 2.9e-118 gapA; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) K00134; Psort location: Cytoplasmic, score: 9.97. (343 aa)
EEU97400.1KEGG: mta:Moth_0429 8.4e-151 mannitol dehydrogenase K00040. (528 aa)
EEU97410.1Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: bth:BT3232 3.4e-99 gluconate 5-dehydrogenase K00046; Psort location: Cytoplasmic, score: 9.97. (266 aa)
EEU97420.1Mannitol dehydrogenase domain protein; KEGG: cac:CAC0695 1.0e-106 altronate oxidoreductase K00041. (504 aa)
EEU97173.1Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 3.9e-66 oxidoreductase; Psort location: Periplasmic, score: 9.44. (331 aa)
gpsAKEGG: ldb:Ldb1959 6.4e-114 gpsA2; glycerol-3-phosphate dehydrogenase K00057; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (375 aa)
EEU97152.1Ketopantoate reductase PanE/ApbA; KEGG: bce:BC3920 0.00030 2-dehydropantoate 2-reductase K00077. (328 aa)
folDTetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (281 aa)
pdxB-2KEGG: son:SO3631 5.6e-67 hprA; glycerate dehydrogenase K00018; Psort location: Cytoplasmic, score: 9.26; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa)
EEU97000.1GroES-like protein; KEGG: bfs:BF1277 2.7e-145 putative zinc-binding alcohol dehydrogenase K00100; Psort location: Cytoplasmic, score: 9.97. (349 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa)
EEU96802.13-hydroxyacyl-CoA dehydrogenase, NAD binding domain protein; KEGG: fnu:FN1019 9.8e-102 3-hydroxybutyryl-CoA dehydrogenase K00074; Psort location: Cytoplasmic, score: 8.96. (290 aa)
EEU96820.1KEGG: aci:ACIAD2466 6.0e-13 putative xanthine dehydrogenase protein; putative xanthine dehydrogenase accessory factor (XdhC) K00087; Psort location: Cytoplasmic, score: 8.96. (322 aa)
LYS1KEGG: spd:SPD_0812 2.4e-178 lys1; saccharopine dehydrogenase K00290. (419 aa)
EEU96231.1KEGG: mta:Moth_1307 5.1e-73 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.96. (411 aa)
dxrKEGG: gvi:gll2252 1.5e-57 deoxyxylulose 5-phosphate reductoisomerase K00099; Psort location: Cytoplasmic, score: 8.96; overlaps another CDS with the same product name. (254 aa)
EEU96221.1Polysaccharide biosynthesis protein; KEGG: lsl:LSL_0995 3.1e-114 UDP-N-acetylglucosamine 4,6-dehydratase / UDP-D-quinovosamine 4-dehydrogenase K00100:K01726; Psort location: CytoplasmicMembrane, score: 10.00. (632 aa)
EEU96207.1Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; KEGG: blo:BL0630 9.6e-182 gdhA; NADP-specific glutamate dehydrogenase K00262; Psort location: Cytoplasmic, score: 9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (450 aa)
EEU96165.1Ketopantoate reductase PanE/ApbA; KEGG: rpb:RPB_0018 2.0e-08 2-dehydropantoate 2-reductase K00077. (308 aa)
EEU96109.1Hypothetical protein; KEGG: hsa:27294 4.3e-12 DHDH; dihydrodiol dehydrogenase (dimeric) K00212. (123 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (252 aa)
asdKEGG: cac:CAC0568 2.0e-126 asd; aspartate semialdehyde dehydrogenase (gene asd) K00133; Belongs to the aspartate-semialdehyde dehydrogenase family. (378 aa)
EEU96065.1Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_3605 6.8e-26 iolG1; myo-inositol 2-dehydrogenase K00010; Psort location: Periplasmic, score: 9.44. (408 aa)
EEU96066.1Oxidoreductase, NAD-binding domain protein; KEGG: cal:orf19.6899 9.2e-19 oxidoreductase K00010; Psort location: Cytoplasmic, score: 8.96. (336 aa)
EEU95983.1KEGG: ade:Adeh_2159 2.9e-31 2-dehydropantoate 2-reductase K00077; Psort location: Cytoplasmic, score: 8.96. (265 aa)
EEU95961.1NAD dependent epimerase/dehydratase family protein; KEGG: bha:BH3365 1.4e-20 rfbD; spore coat polysaccharide synthesis (dTDP-4-dehydrorhamnose reductase) K00067. (277 aa)
EEU95716.1Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: mtu:Rv1544 4.7e-38 possible ketoacyl reductase; Psort location: Cytoplasmic, score: 9.97; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa)
rexCoA binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (213 aa)
cobKprecorrin-6A reductase; KEGG: mta:Moth_1095 2.2e-33 precorrin-6x reductase K03397; Psort location: Cytoplasmic, score: 8.96. (245 aa)
EEU95425.1Putative dipicolinic acid synthetase, A subunit; KEGG: btk:BT9727_3544 5.7e-26 dapA; dipicolinate synthase subunit A K06410. (264 aa)
fabG3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
EEU95187.1KEGG: gme:Gmet_2821 5.4e-37 NAD-dependent epimerase/dehydratase K00091; Psort location: Cytoplasmic, score: 8.96. (342 aa)
EEU95188.1Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: rso:RSc0215 1.7e-26 RS00647; short chain dehydrogenase; Psort location: Cytoplasmic, score: 8.96. (274 aa)
EEU95238.1TrkA N-terminal domain protein. (215 aa)
EEU94944.1Malic enzyme, NAD binding domain protein; KEGG: cpr:CPR_0140 2.1e-131 NAD-dependent malic enzyme K00027; Psort location: Cytoplasmic, score: 8.96. (488 aa)
rfbDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (306 aa)
rfbBKEGG: cpf:CPF_0482 2.1e-145 rfbB; dTDP-glucose 4,6-dehydratase K01710; Psort location: Cytoplasmic, score: 8.96; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (354 aa)
EEU94907.1Hypothetical protein; KEGG: bth:BT3232 2.4e-27 gluconate 5-dehydrogenase K00046; Psort location: Cytoplasmic, score: 9.26. (82 aa)
Your Current Organism:
Faecalibacterium prausnitzii A2165
NCBI taxonomy Id: 411483
Other names: F. prausnitzii A2-165, Faecalibacterium prausnitzii A2-165
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