STRINGSTRING
AAW51_3062 AAW51_3062 AAW51_3082 AAW51_3082 AAW51_3083 AAW51_3083 AAW51_3126 AAW51_3126 cheR-2 cheR-2 AAW51_3161 AAW51_3161 cobA-2 cobA-2 lasT lasT thyA thyA AAW51_3688 AAW51_3688 ubiG ubiG trmD trmD ubiE-2 ubiE-2 AAW51_3795 AAW51_3795 AAW51_3873 AAW51_3873 AAW51_3972 AAW51_3972 cmoA cmoA AAW51_4130 AAW51_4130 AAW51_4229 AAW51_4229 cheR-3 cheR-3 AAW51_4310 AAW51_4310 cheR-4 cheR-4 hemX hemX hemK hemK rsmI rsmI AAW51_4488 AAW51_4488 hemK-2 hemK-2 pilD pilD AAW51_5075 AAW51_5075 metH metH AAW51_5131 AAW51_5131 rsmI-2 rsmI-2 rlmJ rlmJ gidB gidB AAW51_5428 AAW51_5428 hsdM hsdM ypsC ypsC AAW51_0236 AAW51_0236 AAW51_0245 AAW51_0245 rsmE rsmE ksgA ksgA AAW51_0334 AAW51_0334 rsmB rsmB AAW51_0489 AAW51_0489 AAW51_0528 AAW51_0528 AAW51_0530 AAW51_0530 cobL cobL cbiD cbiD cobM cobM AAW51_0568 AAW51_0568 hsdM-2 hsdM-2 bpsB bpsB AAW51_0672 AAW51_0672 AAW51_0891 AAW51_0891 tlyA tlyA rlmI rlmI cheR cheR AAW51_0987 AAW51_0987 AAW51_1041 AAW51_1041 prmA prmA trmL trmL mraW mraW ubiE ubiE AAW51_1304 AAW51_1304 rsmB-2 rsmB-2 rlmH rlmH ogt ogt adaalkA adaalkA AAW51_1611 AAW51_1611 trmB trmB AAW51_1695 AAW51_1695 AAW51_1881 AAW51_1881 AAW51_1995 AAW51_1995 AAW51_2027 AAW51_2027 mnmC mnmC AAW51_2094 AAW51_2094 AAW51_2188 AAW51_2188 AAW51_2203 AAW51_2203 rumA rumA AAW51_2212 AAW51_2212 rlmE rlmE AAW51_2256 AAW51_2256 rlmN rlmN spoU spoU AAW51_2349 AAW51_2349 prmB prmB AAW51_2863 AAW51_2863 metE metE rlmB rlmB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AAW51_3062protein-S-isoprenylcysteine methyltransferase. (205 aa)
AAW51_3082Urea carboxylase. (245 aa)
AAW51_3083Urea carboxylase. (223 aa)
AAW51_3126Lysine methyltransferase. (140 aa)
cheR-2Chemotaxis protein CheR. (274 aa)
AAW51_3161Methyltransferase. (182 aa)
cobA-2uroporphyrin-III methyltransferase; Belongs to the precorrin methyltransferase family. (252 aa)
lasTrRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (274 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (270 aa)
AAW51_3688Hypothetical protein. (204 aa)
ubiG3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (249 aa)
trmDtRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (254 aa)
ubiE-2Dimethylmenaquinone methyltransferase. (257 aa)
AAW51_3795Ferredoxin. (117 aa)
AAW51_3873tRNA(guanine46-N7-)-methyltransferase. (209 aa)
AAW51_3972DNA methylase N-4; Belongs to the N(4)/N(6)-methyltransferase family. (393 aa)
cmoAtRNA (cmo5U34)-methyltransferase. (227 aa)
AAW51_4130Hypothetical protein. (46 aa)
AAW51_4229Plasmid replication/partition related protein. (287 aa)
cheR-3Chemotaxis protein methyltransferase CheR. (276 aa)
AAW51_4310SAM-dependent methyltransferase. (407 aa)
cheR-4Chemotaxis protein CheR; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (285 aa)
hemXuroporphyrin-III methyltransferase. (344 aa)
hemKRelease factor glutamine methyltransferase. (314 aa)
rsmIuroporphyrin-III methyltransferase. (253 aa)
AAW51_4488Methyltransferase type 11. (247 aa)
hemK-2SAM-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (294 aa)
pilDPeptidase A24; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (284 aa)
AAW51_50755-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (897 aa)
metH5-methyltetrahydrofolate--homocysteine methyltransferase. (348 aa)
AAW51_5131SAM-dependent methyltransferase. (293 aa)
rsmI-216S rRNA methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (303 aa)
rlmJCompetence protein ComJ; Specifically methylates the adenine in position 2030 of 23S rRNA. (280 aa)
gidB16S rRNA methyltransferase; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (227 aa)
AAW51_5428Adenylate cyclase. (170 aa)
hsdMType I restriction enzyme M protein. (620 aa)
ypsCRNA methyltransferase; Belongs to the methyltransferase superfamily. (411 aa)
AAW51_0236SAM-dependent methyltransferase. (254 aa)
AAW51_0245Methionine biosynthesis protein MetW. (188 aa)
rsmE16S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (250 aa)
ksgA16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (256 aa)
AAW51_0334Hypothetical protein. (172 aa)
rsmB16S rRNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (454 aa)
AAW51_0489Hypothetical protein. (128 aa)
AAW51_0528Cobalt-precorrin-3b C17-methyltransferase. (486 aa)
AAW51_0530Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. (266 aa)
cobLprecorrin-6Y C5,15-methyltransferase. (443 aa)
cbiDcobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (393 aa)
cobMCobalt-precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family. (263 aa)
AAW51_0568Hypothetical protein. (385 aa)
hsdM-2DNA methyltransferase. (476 aa)
bpsBMethyltransferase. (179 aa)
AAW51_0672Hypothetical protein. (321 aa)
AAW51_0891Transcriptional regulator, MerR family; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. (283 aa)
tlyAHemolysin. (250 aa)
rlmI23S rRNA methyltransferase. (395 aa)
cheRSAM-dependent methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (270 aa)
AAW51_0987Methylase; Belongs to the methyltransferase superfamily. (375 aa)
AAW51_1041Methyltransferase. (193 aa)
prmARibosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (301 aa)
trmLrRNA methylase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (156 aa)
mraW16S rRNA methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (311 aa)
ubiEUbiquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (243 aa)
AAW51_1304BchE/P-methylase family protein. (511 aa)
rsmB-2SAM-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (419 aa)
rlmH50S rRNA methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (156 aa)
ogtCysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (180 aa)
adaalkADNA-3-methyladenine glycosylase II. (510 aa)
AAW51_1611protein-L-isoaspartate O-methyltransferase. (221 aa)
trmBtRNA (guanine-N7)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (212 aa)
AAW51_1695SAM-dependent methyltransferase. (193 aa)
AAW51_1881Hypothetical protein. (230 aa)
AAW51_1995Hypothetical protein. (218 aa)
AAW51_2027uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. (269 aa)
mnmCOxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. (649 aa)
AAW51_2094Adenine-specific methyltransferase. (532 aa)
AAW51_2188Hypothetical protein. (448 aa)
AAW51_2203protein-L-isoaspartate O-methyltransferase. (294 aa)
rumA23S rRNA methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (452 aa)
AAW51_2212Farnesyl cysteine carboxyl-methyltransferase. (223 aa)
rlmERibosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (226 aa)
AAW51_2256Methyltransferase type 11. (275 aa)
rlmN50S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (379 aa)
spoUrRNA methyltransferase. (260 aa)
AAW51_2349SAM-dependent methyltransferase. (222 aa)
prmBprotein-(glutamine-N5) methyltransferase; Belongs to the protein N5-glutamine methyltransferase family. (291 aa)
AAW51_2863ABC transporter ATP-binding protein. (347 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (796 aa)
rlmB23S rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. (243 aa)
Your Current Organism:
Polyangium brachysporum
NCBI taxonomy Id: 413882
Other names: ATCC 53080, DSM 7029, NBRC 100090, [. brachysporum, [Polyangium] brachysporum, strain K481-B101
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.