STRINGSTRING
dnaB dnaB purA purA accC accC accD accD accA accA murAB murAB comB comB glmU glmU prsA prsA hpt-2 hpt-2 coaX coaX thyX thyX sigH sigH nusG nusG rpoB rpoB rpoC rpoC adK adK rpoA rpoA dacA dacA dnaE dnaE pyrK2 pyrK2 guaB guaB guaA guaA pyrB pyrB pyrI pyrI pyrC pyrC pyrF pyrF pyrK pyrK queA queA tgt tgt apt apt relA relA CBO3039 CBO3039 polA polA coaE coaE nadD nadD CBO2983 CBO2983 selA selA holA holA dnaG dnaG sigA sigA purF-2 purF-2 purE purE purC purC purF purF purM purM purN purN purH purH purD purD pyrR-2 pyrR-2 dinB dinB nrdE nrdE nrdF nrdF CBO2723 CBO2723 CBO2715 CBO2715 fliI fliI sigD sigD ntpE ntpE ntpG ntpG ntpA ntpA ntpB ntpB ntpD ntpD CBO2601 CBO2601 CBO2591 CBO2591 purL purL udk udk sigK sigK sigE sigE sigG sigG gmk gmk rpoZ rpoZ coaBC coaBC priA priA coaD coaD ptA ptA ackA ackA pyrH pyrH polC polC nusA nusA ribF ribF purB purB CBO2376 CBO2376 CBO2361 CBO2361 CBO2299 CBO2299 CBO2274 CBO2274 CBO2240 CBO2240 nusB nusB nadK nadK cmk cmk CBO1717 CBO1717 pyrK1 pyrK1 acoC acoC acoX acoX acoA acoA CBO1626 CBO1626 CBO1625 CBO1625 CBO1618 CBO1618 CBO1596 CBO1596 CBO1592 CBO1592 queC queC queE queE queD-2 queD-2 pyrR pyrR nadA nadA nadC nadC CBO1410 CBO1410 CBO1321 CBO1321 dut dut folD folD CBO1157 CBO1157 xpt-2 xpt-2 nrdG-2 nrdG-2 add add asrB asrB CBO0935 CBO0935 CBO0897 CBO0897 CBO0879 CBO0879 CBO0858 CBO0858 CBO0836 CBO0836 queD queD CBO0822 CBO0822 botR botR CBO0768 CBO0768 CBO0736 CBO0736 CBO0674 CBO0674 nadE nadE serS-2 serS-2 xpt xpt CBO0254 CBO0254 rpoN rpoN cinA cinA queG queG CBO0196 CBO0196 CBO0185 CBO0185 murA murA atpC-2 atpC-2 atpD atpD atpG atpG atpA-2 atpA-2 atpH atpH atpB atpB atpC atpC atpA atpA upp upp tdK tdK rho rho pyrG pyrG CBO0105 CBO0105 nrdG nrdG CBO0056 CBO0056 tmk tmk CBO0043A CBO0043A CBO0043 CBO0043 dnaX dnaX serS serS dnaN dnaN pyrD pyrD pyrE pyrE sigF sigF hpt hpt
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (445 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa)
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (279 aa)
murABUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (421 aa)
comBPutative 2-phosphosulfolactate phosphatase; Belongs to the ComB family. (223 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (457 aa)
prsARibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (319 aa)
hpt-2Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (181 aa)
coaXConserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (258 aa)
thyXThymidylate synthase complementing protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (252 aa)
sigHRNA polymerase sigma-H factor; Belongs to the sigma-70 factor family. (190 aa)
nusGTranscription antitermination protein; Participates in transcription elongation, termination and antitermination. (174 aa)
rpoBDNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1232 aa)
rpoCDNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1178 aa)
adKAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa)
rpoADNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (315 aa)
dacAConserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (282 aa)
dnaEDNA polymerase III alpha subunit. (1185 aa)
pyrK2Putative dihydroorotate dehydrogenase electron transfer subunit; Self match: 67.698 38dentity (67.9310ngapped) in 291 aa overlap with CBO1644. (296 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (484 aa)
guaAGMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. (510 aa)
pyrBAspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (307 aa)
pyrIAspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. (146 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (396 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (283 aa)
pyrKDihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (251 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (341 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (376 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (172 aa)
relAGTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (723 aa)
CBO3039Conserved hypothetical protein. (173 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (875 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (212 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (201 aa)
CBO2983Putative phosphohydrolase. (189 aa)
selAL-seryl-tRNA(sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (462 aa)
holAConserved hypothetical protein. (343 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (590 aa)
sigARNA polymerase sigma factor (sigma-43); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (361 aa)
purF-2Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (460 aa)
purEPhosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (159 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (234 aa)
purFAmidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (482 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (334 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (205 aa)
purHBifunctional purine biosynthesis protein [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase. (499 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (413 aa)
pyrR-2Pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (182 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (349 aa)
nrdERibonucleoside-diphosphate reductase 2 alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (763 aa)
nrdFRibonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (342 aa)
CBO2723Conserved hypothetical protein. (342 aa)
CBO2715Probable DTDP-4-dehydrorhamnose 3,5-epimerase. (177 aa)
fliIFlagellum-specific ATP synthase. (438 aa)
sigDRNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (242 aa)
ntpEV-type sodium ATP synthase subunit E. (200 aa)
ntpGV-type sodium ATP synthase subunit G; Produces ATP from ADP in the presence of a proton gradient across the membrane. (102 aa)
ntpAV-type sodium ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (592 aa)
ntpBV-type sodium ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (461 aa)
ntpDV-type sodium ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (219 aa)
CBO2601Putative transferase; No significant database matches to the full length CDS. (1621 aa)
CBO2591Hypothetical protein; Poor database matches. C-terminus is weakly similar to the C-terminal region of Methanococcus maripaludis seryl-tRNA synthetase SerS or MMP0879 SWALL:SYS_METMP (SWALL:O30520) (514 aa) fasta scores: E(): 5.2e-12, 22.86 id in 363 aa. (397 aa)
purLFormylglycinamidine ribonucleotide synthetase. (1221 aa)
udkUridine kinase. (206 aa)
sigKRNA polymerase sigma-28 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (234 aa)
sigERNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (235 aa)
sigGRNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (257 aa)
gmkPutative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (209 aa)
rpoZPutative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (72 aa)
coaBCPutative coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (395 aa)
priAPutative primosomal protein n'(replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (735 aa)
coaDPutative phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (164 aa)
ptAPhosphate acetyltransferase. (332 aa)
ackAConserved hypothetical protein (pseudogene); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (238 aa)
polCDNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1432 aa)
nusAPutative transcription elongation protein NusA; Participates in both transcription termination and antitermination. (457 aa)
ribFPutative riboflavin biosynthesis protein RibC; Belongs to the ribF family. (306 aa)
purBAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (476 aa)
CBO2376N-terminal region is similar to Bacillus subtilis RNA polymerase sigma-E factor precursor SigE or SpoIIGB or BSU15320 SWALL:RPSE_BACSU (SWALL:P06222) (239 aa) fasta scores: E(): 7.1e-08, 32.95 38d in 176 aa. (317 aa)
CBO2361Hypothetical phage protein. (177 aa)
CBO2299Putative RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (170 aa)
CBO2274Putative ferredoxin; Similar to Clostridium acetobutylicum predicted flavodoxin oxidoreductase CAC1860 SWALL:Q97HZ6 (EMBL:AE007694) (328 aa) fasta scores: E(): 8.3e-70,54.87 38d in 328 aa. C-terminal region is weakly similar to Bacillus subtilis dihydroorotate dehydrogenase electron transfer subunit PyrK or PyrZ or BSU15530 SWALL:PYRK_BACSU (SWALL:P25983) (256 aa) fasta scores: E(): 1.4e-06, 24.47 id in 237 aa. (327 aa)
CBO2240Acetyltransferase (GNAT) family protein. (149 aa)
nusBN utilization substance protein b; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (143 aa)
nadKProbable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (281 aa)
cmkCytidylate kinase. (217 aa)
CBO1717Phage protein. (171 aa)
pyrK1Putative dihydroorotate dehydrogenase electron transfer subunit; Also similar to CBO3305 (67.698 38d. in 291 aa overlap). (295 aa)
acoCDihydrolipoamide acetyltransferase component of acetoin dehydrogenase complex. (436 aa)
acoXAcetoin catabolism protein X; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (331 aa)
acoAAcetoin:2,6-dichlorophenolindophenol oxidoreductase alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (327 aa)
CBO1626Putative membrane protein. (484 aa)
CBO1625RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (190 aa)
CBO1618Weak similarity to the listed RNA polymerase sigma factors. (176 aa)
CBO1596Putative GTP pyrophosphatase. (271 aa)
CBO1592Probable gene remnant. Similar to the N-terminus of several two-component response regulators; was marked partial. (186 aa)
queCConserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). (219 aa)
queEPutative radical SAM-superfamily protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (221 aa)
queD-2Conserved hypothetical protein. (143 aa)
pyrRPutative pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (178 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (304 aa)
nadCNicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. (278 aa)
CBO1410Putative nicotinate phosphribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (493 aa)
CBO1321Putative DNA helicase. (855 aa)
dutPutative deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (208 aa)
folDPutative methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (282 aa)
CBO1157Putative membrane protein. (388 aa)
xpt-2Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (190 aa)
nrdG-2Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (197 aa)
addAdenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (335 aa)
asrBAnaerobic sulfite reductase subunit B. (265 aa)
CBO0935Conserved hypothetical protein. (177 aa)
CBO0897Conserved hypothetical protein. (195 aa)
CBO0879Putative iron-sulfur cluster-binding protein. (268 aa)
CBO0858Conserved hypothetical protein. (171 aa)
CBO0836RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (170 aa)
queDPutative 6-pyruvoyl tetrahydrobiopterin synthase. (117 aa)
CBO0822Conserved hypothetical protein. (258 aa)
botRRNA polymerase ECF-type sigma factor; Previously sequenced as Clostridium botulinum hypothetical protein p-21 or botR SWALL:Q57176 (EMBL:X79104) (178 aa) fasta scores: E(): 9.6e-61, 100 38d in 178 aa. (178 aa)
CBO0768Putative phage-related deoxyuridylate hydroxymethyltransferase. (324 aa)
CBO0736Putative RNA polymerase sigma factor; Belongs to the sigma-70 factor family. (179 aa)
CBO0674RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa)
nadEGlutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (638 aa)
serS-2seryl-tRNA synthetase. (425 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (190 aa)
CBO0254Putative acetyltransferase; Similar to Listeria innocua hypothetical protein Lin2361 SWALL:Q929B6 (EMBL:AL596172) (291 aa) fasta scores: E(): 3.5e-39, 37.75 38d in 294 aa, and to Bacillus halodurans hypothetical protein Bh3929 bh3929 SWALL:Q9K606 (EMBL:AP001520) (286 aa) fasta scores: E(): 1.7e-23,30.47 38d in 292 aa. (300 aa)
rpoNSimilar to Alcaligenes eutrophus RNA polymerase sigma-54 factor RpoN or NtrA or Hno SWALL:RP54_ALCEU (SWALL:P28615) (493 aa) fasta scores: E(): 6.6e-36, 33.6 id in 494 aa, and to Clostridium tetani RNA polymerase sigma-54 factor RpoN or ctc00376 SWALL:Q898R6 (EMBL:AE015937) (461 aa) fasta scores: E(): 2.6e-87,60.47 38d in 463 aa. (457 aa)
cinAPutative molybdopterin binding; Similar to Bacillus subtilis cina-like protein CinA or bsu16930 SWALL:CINA_BACSU (SWALL:P46323) (416 aa) fasta scores: E(): 6.2e-57, 44.92 38d in 394 aa, and to Clostridium acetobutylicum competence-damage inducible protein, cina cac3586 SWALL:Q97D94 (EMBL:AE007855) (411 aa) fasta scores: E(): 1.3e-92, 60.29 38d in 408 aa; Belongs to the CinA family. (409 aa)
queGSimilar to Clostridium tetani iron-sulfur cluster-binding protein ctc00352 SWALL:Q898T9 (EMBL:AE015937) (327 aa) fasta scores: E(): 2.3e-75,61.12 38d in 319 aa. (321 aa)
CBO0196Putative kinase; Similar to Clostridium tetani uridine kinase ctc00344 SWALL:Q898U6 (EMBL:AE015937) (552 aa) fasta scores: E(): 6.7e-122, 61.05 38d in 552 aa, and to Clostridium acetobutylicum fision threonyl-trna synthetase cac0672 SWALL:Q97L90 (EMBL:AE007582) (553 aa) fasta scores: E(): 4.3e-123, 61.84 38d in 553 aa. (552 aa)
CBO0185Putative guanosine 3',5'-bis-pyrophosphate (ppGpp) synthesis/degradation protein; Similar to Clostridium tetani GTP pyrophosphokinase ctc00336 SWALL:Q898V3 (EMBL:AE015937) (262 aa) fasta scores: E(): 8.5e-70, 77.86 38d in 262 aa. (262 aa)
murAudp-N-acetylglucosamine 1-carboxyvinyltransferase 1; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa)
atpC-2ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. (133 aa)
atpDATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (463 aa)
atpGATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (282 aa)
atpA-2ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (504 aa)
atpHATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (179 aa)
atpBATP synthase B chain; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (159 aa)
atpCATP synthase c chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (79 aa)
atpAATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (226 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)
tdKThymidine kinase; Similar to Rhodothermus sp. thymidine kinase Tdk SWALL:KITH_RHOSI (SWALL:Q9ZIG2) (213 aa) fasta scores: E(): 2.6e-34, 53.26 38d in 184 aa, and to Clostridium acetobutylicum thymidine kinase cac2887 SWALL:Q97F65 (EMBL:AE007786) (195 aa) fasta scores: E(): 5.1e-56,77.48 38d in 191 aa. (191 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (481 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (533 aa)
CBO0105Conserved hypothetical protein; Similar to Myxococcus xanthus phosphoribosyl amino imidizole carboxylase-like protein SWALL:Q8VQZ2 (EMBL:AF449411) (250 aa) fasta scores: E(): 2.7e-43,52.43 38d in 246 aa, and to Clostridium acetobutylicum ncair mutase cac0776 SWALL:Q97KZ0 (EMBL:AE007592) (248 aa) fasta scores: E(): 4.2e-63, 71.37 38d in 248 aa. (248 aa)
nrdGAnaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (171 aa)
CBO0056Similar to Escherichia coli DNA polymerase III,delta' subunit HolB or b1099 SWALL:HOLB_ECOLI (SWALL:P28631) (334 aa) fasta scores: E(): 1.3e-05, 22.05 id in 263 aa, and to Clostridium tetani DNA polymerase III delta subunit ctc00221 SWALL:Q899F8 (EMBL:AE015936) (322 aa) fasta scores: E(): 1.1e-52, 53.35 38d in 313 aa. (314 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (231 aa)
CBO0043ASimilar to Clostridium tetani conserved protein ctc01787 SWALL:Q893M8 (EMBL:AE015942) (477 aa) fasta scores: E(): 5.7e-98, 58.62 38d in 481 aa, and to Bacillus anthracis conserved domain protein ba1754 SWALL:Q81SB1 (EMBL:AE017029) (366 aa) fasta scores: E(): 9.9e-18, 27.1 id in 380 aa. (480 aa)
CBO0043Similar to Clostridium tetani RNA polymerase sigma factor ctc01788 SWALL:Q893M7 (EMBL:AE015942) (212 aa) fasta scores: E(): 2.1e-44, 65.95 38d in 188 aa, and to Clostridium acetobutylicum predicted sigma factor cac1766 SWALL:Q97I86 (EMBL:AE007685) (185 aa) fasta scores: E(): 2.2e-20, 37.64 38d in 178 aa; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (541 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa)
dnaNDNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] (367 aa)
pyrDDihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (298 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (191 aa)
sigFRNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (251 aa)
hptHypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (181 aa)
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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