(38 nodes) Mixed, incl. Cell-extracellular matrix interactions, and Alpha-catenin/vinculin-like superfamily network (Seriola dumerili)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	itga11	Integrin, alpha 11a; Belongs to the integrin alpha chain family. (1203 aa)
	ctnna2	Catenin (cadherin-associated protein), alpha 2. (905 aa)
	LOC111227470	Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (527 aa)
	LOC111220639	Uncharacterized protein; Belongs to the peptidase C2 family. (700 aa)
	LOC111220638	Calpain 2, (m/II) large subunit, like; Belongs to the peptidase C2 family. (672 aa)
	LOC111234414	Integrin linked kinase. (452 aa)
	ACTN4	Actinin alpha 4. (932 aa)
	LOC111218754	Talin 2a. (2542 aa)
	LOC111222518	Parvin, alpha a. (390 aa)
	LOC111217917	SH3 and PX domains 2Aa. (1067 aa)
	LOC111238392	LIM domain-containing protein. (335 aa)
	LOC111225279	Actinin, alpha 1. (885 aa)
	ctnna1	Catenin (cadherin-associated protein), alpha 1. (921 aa)
	tln2	Talin 2b. (2552 aa)
	ILK	Integrin linked kinase. (452 aa)
	zyx	Zyxin. (623 aa)
	raver2	Ribonucleoprotein, PTB-binding 2. (878 aa)
	LOC111218163	LIM domain-containing protein. (393 aa)
	LOC111235396	Actinin, alpha 2b. (896 aa)
	ENSSDUP00000025524	Uncharacterized protein. (523 aa)
	pdlim1	PDZ and LIM domain 1 (elfin). (322 aa)
	LOC111220765	Sorbin and SH3 domain containing 1. (908 aa)
	ENSSDUP00000026236	Uncharacterized protein. (455 aa)
	LOC111234167	PDZ and LIM domain 5b. (614 aa)
	pdlim4	PDZ and LIM domain 4. (363 aa)
	LOC111228592	PDZ and LIM domain 2 (mystique). (367 aa)
	LOC111231492	Sorbin and SH3 domain containing 3. (610 aa)
	LOC111219856	Vinculin b. (1066 aa)
	rsu1	Ras suppressor protein 1. (277 aa)
	tln1	Talin 1. (2276 aa)
	LOC111237555	Calpain 2, (m/II) large subunit, like; Belongs to the peptidase C2 family. (701 aa)
	ENSSDUP00000030051	calpain_III domain-containing protein. (117 aa)
	LOC111237556	Calpain 2, (m/II) large subunit b; Belongs to the peptidase C2 family. (698 aa)
	pdlim5	PDZ and LIM domain 5a. (571 aa)
	LOC111221651	Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (530 aa)
	LOC111234345	Vinculin a. (1158 aa)
	parvg	Parvin, gamma. (320 aa)
	parvb	Parvin, beta. (365 aa)

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN4	LOC111219856	ENSSDUP00000004192	ENSSDUP00000028778	Actinin alpha 4.	Vinculin b.	0.965
ACTN4	LOC111222518	ENSSDUP00000004192	ENSSDUP00000005511	Actinin alpha 4.	Parvin, alpha a.	0.618
ACTN4	LOC111225279	ENSSDUP00000004192	ENSSDUP00000008033	Actinin alpha 4.	Actinin, alpha 1.	0.900
ACTN4	LOC111234167	ENSSDUP00000004192	ENSSDUP00000026436	Actinin alpha 4.	PDZ and LIM domain 5b.	0.521
ACTN4	LOC111234345	ENSSDUP00000004192	ENSSDUP00000032206	Actinin alpha 4.	Vinculin a.	0.666
ACTN4	ctnna1	ENSSDUP00000004192	ENSSDUP00000012855	Actinin alpha 4.	Catenin (cadherin-associated protein), alpha 1.	0.931
ACTN4	ctnna2	ENSSDUP00000004192	ENSSDUP00000001004	Actinin alpha 4.	Catenin (cadherin-associated protein), alpha 2.	0.931
ACTN4	itga11	ENSSDUP00000004192	ENSSDUP00000000062	Actinin alpha 4.	Integrin, alpha 11a; Belongs to the integrin alpha chain family.	0.666
ACTN4	parvb	ENSSDUP00000004192	ENSSDUP00000032288	Actinin alpha 4.	Parvin, beta.	0.618
ACTN4	parvg	ENSSDUP00000004192	ENSSDUP00000032276	Actinin alpha 4.	Parvin, gamma.	0.439
ACTN4	pdlim1	ENSSDUP00000004192	ENSSDUP00000026053	Actinin alpha 4.	PDZ and LIM domain 1 (elfin).	0.404
ACTN4	pdlim5	ENSSDUP00000004192	ENSSDUP00000030305	Actinin alpha 4.	PDZ and LIM domain 5a.	0.521
ACTN4	zyx	ENSSDUP00000004192	ENSSDUP00000015500	Actinin alpha 4.	Zyxin.	0.931
ENSSDUP00000025524	LOC111217917	ENSSDUP00000025524	ENSSDUP00000006972	Uncharacterized protein.	SH3 and PX domains 2Aa.	0.495
ENSSDUP00000025524	LOC111218754	ENSSDUP00000025524	ENSSDUP00000004640	Uncharacterized protein.	Talin 2a.	0.439
ENSSDUP00000025524	LOC111219856	ENSSDUP00000025524	ENSSDUP00000028778	Uncharacterized protein.	Vinculin b.	0.724
ENSSDUP00000025524	LOC111221651	ENSSDUP00000025524	ENSSDUP00000031665	Uncharacterized protein.	Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.	0.430
ENSSDUP00000025524	LOC111227470	ENSSDUP00000025524	ENSSDUP00000001811	Uncharacterized protein.	Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.	0.430
ENSSDUP00000025524	LOC111234345	ENSSDUP00000025524	ENSSDUP00000032206	Uncharacterized protein.	Vinculin a.	0.724
ENSSDUP00000025524	ctnna1	ENSSDUP00000025524	ENSSDUP00000012855	Uncharacterized protein.	Catenin (cadherin-associated protein), alpha 1.	0.462