(6 nodes) Mre11 complex, and BRCA1-BARD1 complex network (Seriola dumerili)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Rbbp8	SAE2 domain-containing protein. (86 aa)
	atm	Non-specific serine/threonine protein kinase. (2999 aa)
	bard1	BRCA1 associated RING domain 1. (809 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1312 aa)
	mre11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (696 aa)
	brca1	Uncharacterized protein. (1251 aa)

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Rbbp8	atm	ENSSDUP00000009367	ENSSDUP00000015925	SAE2 domain-containing protein.	Non-specific serine/threonine protein kinase.	0.915
Rbbp8	bard1	ENSSDUP00000009367	ENSSDUP00000019914	SAE2 domain-containing protein.	BRCA1 associated RING domain 1.	0.985
Rbbp8	brca1	ENSSDUP00000009367	ENSSDUP00000029899	SAE2 domain-containing protein.	Uncharacterized protein.	0.998
Rbbp8	mre11	ENSSDUP00000009367	ENSSDUP00000029727	SAE2 domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.996
Rbbp8	rad50	ENSSDUP00000009367	ENSSDUP00000029174	SAE2 domain-containing protein.	RAD50 homolog, double strand break repair protein.	0.995
atm	Rbbp8	ENSSDUP00000015925	ENSSDUP00000009367	Non-specific serine/threonine protein kinase.	SAE2 domain-containing protein.	0.915
atm	bard1	ENSSDUP00000015925	ENSSDUP00000019914	Non-specific serine/threonine protein kinase.	BRCA1 associated RING domain 1.	0.987
atm	brca1	ENSSDUP00000015925	ENSSDUP00000029899	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.979
atm	mre11	ENSSDUP00000015925	ENSSDUP00000029727	Non-specific serine/threonine protein kinase.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.999
atm	rad50	ENSSDUP00000015925	ENSSDUP00000029174	Non-specific serine/threonine protein kinase.	RAD50 homolog, double strand break repair protein.	0.998
bard1	Rbbp8	ENSSDUP00000019914	ENSSDUP00000009367	BRCA1 associated RING domain 1.	SAE2 domain-containing protein.	0.985
bard1	atm	ENSSDUP00000019914	ENSSDUP00000015925	BRCA1 associated RING domain 1.	Non-specific serine/threonine protein kinase.	0.987
bard1	brca1	ENSSDUP00000019914	ENSSDUP00000029899	BRCA1 associated RING domain 1.	Uncharacterized protein.	0.999
bard1	mre11	ENSSDUP00000019914	ENSSDUP00000029727	BRCA1 associated RING domain 1.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.980
bard1	rad50	ENSSDUP00000019914	ENSSDUP00000029174	BRCA1 associated RING domain 1.	RAD50 homolog, double strand break repair protein.	0.969
brca1	Rbbp8	ENSSDUP00000029899	ENSSDUP00000009367	Uncharacterized protein.	SAE2 domain-containing protein.	0.998
brca1	atm	ENSSDUP00000029899	ENSSDUP00000015925	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.979
brca1	bard1	ENSSDUP00000029899	ENSSDUP00000019914	Uncharacterized protein.	BRCA1 associated RING domain 1.	0.999
brca1	mre11	ENSSDUP00000029899	ENSSDUP00000029727	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.984
brca1	rad50	ENSSDUP00000029899	ENSSDUP00000029174	Uncharacterized protein.	RAD50 homolog, double strand break repair protein.	0.957