19 items (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (439 aa)
	dtl	Denticleless E3 ubiquitin protein ligase homolog (Drosophila). (657 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	Parp10	Poly [ADP-ribose] polymerase. (256 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (386 aa)
	rev3l	REV3 like, DNA directed polymerase zeta catalytic subunit. (2803 aa)
	polh	Polymerase (DNA directed), eta. (690 aa)
	vcp	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	pole2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (526 aa)
	polk	Polymerase (DNA directed) kappa. (884 aa)
	pold1	DNA polymerase. (1121 aa)
	zbtb1	Zinc finger and BTB domain containing 1. (686 aa)
	pclaf	PCNA clamp associated factor. (117 aa)
	pold2	Polymerase (DNA directed), delta 2, regulatory subunit. (491 aa)
	poli	Polymerase (DNA directed) iota. (728 aa)
	LOC111229268	Zgc:136908; Belongs to the AAA ATPase family. (708 aa)
	rev1	REV1 DNA directed polymerase. (1431 aa)
	sprtn	SprT-like N-terminal domain. (624 aa)
	primpol	Primase and polymerase (DNA-directed). (540 aa)

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111229268	pcna	ENSSDUP00000011790	ENSSDUP00000004184	Zgc:136908; Belongs to the AAA ATPase family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.651
LOC111229268	polh	ENSSDUP00000011790	ENSSDUP00000015777	Zgc:136908; Belongs to the AAA ATPase family.	Polymerase (DNA directed), eta.	0.565
LOC111229268	poli	ENSSDUP00000011790	ENSSDUP00000031056	Zgc:136908; Belongs to the AAA ATPase family.	Polymerase (DNA directed) iota.	0.495
LOC111229268	sprtn	ENSSDUP00000011790	ENSSDUP00000007071	Zgc:136908; Belongs to the AAA ATPase family.	SprT-like N-terminal domain.	0.854
LOC111229268	vcp	ENSSDUP00000011790	ENSSDUP00000020163	Zgc:136908; Belongs to the AAA ATPase family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.900
dtl	pclaf	ENSSDUP00000004294	ENSSDUP00000029649	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	PCNA clamp associated factor.	0.597
dtl	pcna	ENSSDUP00000004294	ENSSDUP00000004184	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.985
dtl	pold1	ENSSDUP00000004294	ENSSDUP00000023525	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	DNA polymerase.	0.754
dtl	pold2	ENSSDUP00000004294	ENSSDUP00000030358	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	Polymerase (DNA directed), delta 2, regulatory subunit.	0.762
dtl	pole2	ENSSDUP00000004294	ENSSDUP00000021487	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.863
dtl	rev3l	ENSSDUP00000004294	ENSSDUP00000014191	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.635
pclaf	dtl	ENSSDUP00000029649	ENSSDUP00000004294	PCNA clamp associated factor.	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	0.597
pclaf	pcna	ENSSDUP00000029649	ENSSDUP00000004184	PCNA clamp associated factor.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.963
pclaf	pold1	ENSSDUP00000029649	ENSSDUP00000023525	PCNA clamp associated factor.	DNA polymerase.	0.507
pclaf	pold2	ENSSDUP00000029649	ENSSDUP00000030358	PCNA clamp associated factor.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.616
pclaf	pole2	ENSSDUP00000029649	ENSSDUP00000021487	PCNA clamp associated factor.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.633
pcna	LOC111229268	ENSSDUP00000004184	ENSSDUP00000011790	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Zgc:136908; Belongs to the AAA ATPase family.	0.651
pcna	dtl	ENSSDUP00000004184	ENSSDUP00000004294	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	0.985
pcna	pclaf	ENSSDUP00000004184	ENSSDUP00000029649	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	PCNA clamp associated factor.	0.963
pcna	pold1	ENSSDUP00000004184	ENSSDUP00000023525	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase.	0.999