17 items (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mcm6	DNA helicase; Belongs to the MCM family. (815 aa)
	cdt1	Chromatin licensing and DNA replication factor 1. (534 aa)
	mcm4	DNA helicase; Belongs to the MCM family. (861 aa)
	ZNF830	Zinc finger protein 830. (346 aa)
	DONSON	Downstream neighbor of SON. (626 aa)
	lig1	DNA ligase. (616 aa)
	gins1	GINS complex subunit 1 (Psf1 homolog). (196 aa)
	gmnn	Geminin DNA replication inhibitor. (215 aa)
	mcm2	DNA helicase; Belongs to the MCM family. (888 aa)
	mcm3	DNA helicase; Belongs to the MCM family. (815 aa)
	ENSSDUP00000015520	BRCA2 DNA repair associated. (3048 aa)
	LOC111237687	ATPase family AAA domain containing 5b. (887 aa)
	rad51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (389 aa)
	atad5	ATPase family AAA domain containing 5a. (1852 aa)
	gins3	GINS complex subunit 3. (211 aa)
	pola1	DNA polymerase. (1474 aa)
	cdc45	CDC45 cell division cycle 45 homolog (S. cerevisiae). (576 aa)

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DONSON	cdc45	ENSSDUP00000028378	ENSSDUP00000003823	Downstream neighbor of SON.	CDC45 cell division cycle 45 homolog (S. cerevisiae).	0.560
DONSON	cdt1	ENSSDUP00000028378	ENSSDUP00000021969	Downstream neighbor of SON.	Chromatin licensing and DNA replication factor 1.	0.452
DONSON	mcm2	ENSSDUP00000028378	ENSSDUP00000012879	Downstream neighbor of SON.	DNA helicase; Belongs to the MCM family.	0.738
DONSON	mcm3	ENSSDUP00000028378	ENSSDUP00000010875	Downstream neighbor of SON.	DNA helicase; Belongs to the MCM family.	0.545
DONSON	mcm4	ENSSDUP00000028378	ENSSDUP00000024940	Downstream neighbor of SON.	DNA helicase; Belongs to the MCM family.	0.599
DONSON	mcm6	ENSSDUP00000028378	ENSSDUP00000006275	Downstream neighbor of SON.	DNA helicase; Belongs to the MCM family.	0.508
ENSSDUP00000015520	LOC111237687	ENSSDUP00000015520	ENSSDUP00000000533	BRCA2 DNA repair associated.	ATPase family AAA domain containing 5b.	0.650
ENSSDUP00000015520	atad5	ENSSDUP00000015520	ENSSDUP00000002767	BRCA2 DNA repair associated.	ATPase family AAA domain containing 5a.	0.650
ENSSDUP00000015520	cdc45	ENSSDUP00000015520	ENSSDUP00000003823	BRCA2 DNA repair associated.	CDC45 cell division cycle 45 homolog (S. cerevisiae).	0.538
ENSSDUP00000015520	lig1	ENSSDUP00000015520	ENSSDUP00000029187	BRCA2 DNA repair associated.	DNA ligase.	0.433
ENSSDUP00000015520	pola1	ENSSDUP00000015520	ENSSDUP00000003623	BRCA2 DNA repair associated.	DNA polymerase.	0.605
ENSSDUP00000015520	rad51	ENSSDUP00000015520	ENSSDUP00000001818	BRCA2 DNA repair associated.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.999
LOC111237687	ENSSDUP00000015520	ENSSDUP00000000533	ENSSDUP00000015520	ATPase family AAA domain containing 5b.	BRCA2 DNA repair associated.	0.650
LOC111237687	cdc45	ENSSDUP00000000533	ENSSDUP00000003823	ATPase family AAA domain containing 5b.	CDC45 cell division cycle 45 homolog (S. cerevisiae).	0.747
LOC111237687	cdt1	ENSSDUP00000000533	ENSSDUP00000021969	ATPase family AAA domain containing 5b.	Chromatin licensing and DNA replication factor 1.	0.690
LOC111237687	gins3	ENSSDUP00000000533	ENSSDUP00000003197	ATPase family AAA domain containing 5b.	GINS complex subunit 3.	0.414
LOC111237687	lig1	ENSSDUP00000000533	ENSSDUP00000029187	ATPase family AAA domain containing 5b.	DNA ligase.	0.820
LOC111237687	mcm2	ENSSDUP00000000533	ENSSDUP00000012879	ATPase family AAA domain containing 5b.	DNA helicase; Belongs to the MCM family.	0.759
LOC111237687	mcm4	ENSSDUP00000000533	ENSSDUP00000024940	ATPase family AAA domain containing 5b.	DNA helicase; Belongs to the MCM family.	0.636
LOC111237687	mcm6	ENSSDUP00000000533	ENSSDUP00000006275	ATPase family AAA domain containing 5b.	DNA helicase; Belongs to the MCM family.	0.561