(43 nodes) Axon extension network (Seriola dumerili)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111229784	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2370 aa)
	LOC111229493	Survival of motor neuron 1, telomeric. (297 aa)
	LOC111220461	Family with sequence similarity 53 member B. (423 aa)
	Auts2	Si:dkey-33o22.1. (89 aa)
	LOC111222836	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (790 aa)
	ednra	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (451 aa)
	LOC111219856	Vinculin b. (1066 aa)
	LOC111221027	Sema domain-containing protein. (1042 aa)
	sema5b	Sema domain-containing protein. (1041 aa)
	mycbp2	MYC binding protein 2. (4561 aa)
	LOC111218402	Uncharacterized protein; Belongs to the semaphorin family. (635 aa)
	edn1	Endothelin 1. (187 aa)
	srf	Serum response factor b. (639 aa)
	ssna1	Sjogren syndrome nuclear autoantigen 1. (136 aa)
	LOC111232433	Slit homolog 3 (Drosophila). (1494 aa)
	spast	Spastin; Belongs to the AAA ATPase family. (464 aa)
	LOC111222406	Si:ch211-113g11.6; Belongs to the semaphorin family. (622 aa)
	cyfip1	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
	LOC111228169	Endothelin 2. (172 aa)
	LOC111223136	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2357 aa)
	ENSSDUP00000000417	SPG11 vesicle trafficking associated, spatacsin. (1365 aa)
	ryk	Receptor like tyrosine kinase. (629 aa)
	ulk2	Unc-51 like autophagy activating kinase 2. (1042 aa)
	ubap1	Ubiquitin associated protein 1. (465 aa)
	slit1	Slit homolog 1a (Drosophila). (1456 aa)
	slit2	Slit homolog 2 (Drosophila). (1388 aa)
	LOC111231860	Unc-51 like autophagy activating kinase 1a. (921 aa)
	LOC111224461	Doublecortin-like kinase 1b. (759 aa)
	dcx	Uncharacterized protein. (468 aa)
	sema7a	Semaphorin 7A; Belongs to the semaphorin family. (635 aa)
	LOC111237574	MADS-box domain-containing protein. (520 aa)
	ulk1	Unc-51 like autophagy activating kinase 1. (1027 aa)
	LOC111238733	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b. (1536 aa)
	FAM53B	Family with sequence similarity 53 member B. (454 aa)
	ENSSDUP00000021421	Uncharacterized protein. (515 aa)
	dclk1	Doublecortin-like kinase 1a. (760 aa)
	c9orf72	Zgc:100846. (462 aa)
	LOC111235880	Slit homolog 1b (Drosophila). (1430 aa)
	LOC111222791	Thrombospondin, type I, domain containing 7Aa. (1647 aa)
	LOC111234345	Vinculin a. (1158 aa)
	LOC111221565	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (805 aa)
	LOC111239929	Sema domain-containing protein. (1121 aa)
	LOC111239714	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (435 aa)

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSDUP00000000417	spast	ENSSDUP00000000417	ENSSDUP00000003256	SPG11 vesicle trafficking associated, spatacsin.	Spastin; Belongs to the AAA ATPase family.	0.585
ENSSDUP00000021421	LOC111219856	ENSSDUP00000021421	ENSSDUP00000028778	Uncharacterized protein.	Vinculin b.	0.469
ENSSDUP00000021421	LOC111234345	ENSSDUP00000021421	ENSSDUP00000032206	Uncharacterized protein.	Vinculin a.	0.469
LOC111219856	ENSSDUP00000021421	ENSSDUP00000028778	ENSSDUP00000021421	Vinculin b.	Uncharacterized protein.	0.469
LOC111219856	LOC111238733	ENSSDUP00000028778	ENSSDUP00000030151	Vinculin b.	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b.	0.469
LOC111223136	LOC111232433	ENSSDUP00000000515	ENSSDUP00000003681	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Slit homolog 3 (Drosophila).	0.412
LOC111223136	LOC111235880	ENSSDUP00000000515	ENSSDUP00000018957	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Slit homolog 1b (Drosophila).	0.412
LOC111223136	slit1	ENSSDUP00000000515	ENSSDUP00000031481	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Slit homolog 1a (Drosophila).	0.412
LOC111223136	slit2	ENSSDUP00000000515	ENSSDUP00000031490	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Slit homolog 2 (Drosophila).	0.412
LOC111224461	dclk1	ENSSDUP00000016005	ENSSDUP00000019574	Doublecortin-like kinase 1b.	Doublecortin-like kinase 1a.	0.541
LOC111224461	dcx	ENSSDUP00000016005	ENSSDUP00000013447	Doublecortin-like kinase 1b.	Uncharacterized protein.	0.631
LOC111228169	LOC111239714	ENSSDUP00000001748	ENSSDUP00000032909	Endothelin 2.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.957
LOC111228169	edn1	ENSSDUP00000001748	ENSSDUP00000009806	Endothelin 2.	Endothelin 1.	0.613
LOC111228169	ednra	ENSSDUP00000001748	ENSSDUP00000028254	Endothelin 2.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.957
LOC111229784	LOC111232433	ENSSDUP00000032764	ENSSDUP00000003681	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Slit homolog 3 (Drosophila).	0.412
LOC111229784	LOC111235880	ENSSDUP00000032764	ENSSDUP00000018957	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Slit homolog 1b (Drosophila).	0.412
LOC111229784	slit1	ENSSDUP00000032764	ENSSDUP00000031481	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Slit homolog 1a (Drosophila).	0.412
LOC111229784	slit2	ENSSDUP00000032764	ENSSDUP00000031490	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Slit homolog 2 (Drosophila).	0.412
LOC111231860	c9orf72	ENSSDUP00000031602	ENSSDUP00000019100	Unc-51 like autophagy activating kinase 1a.	Zgc:100846.	0.939
LOC111231860	ulk1	ENSSDUP00000031602	ENSSDUP00000030142	Unc-51 like autophagy activating kinase 1a.	Unc-51 like autophagy activating kinase 1.	0.902