(28 nodes) Cellular response to hydrogen peroxide network (Seriola dumerili)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tnfaip3	Tumor necrosis factor, alpha-induced protein 3. (825 aa)
	ankzf1	Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (736 aa)
	oser1	Oxidative stress responsive serine-rich 1. (477 aa)
	LOC111231057	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
	LOC111231217	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
	ENSSDUP00000023221	Aquaporin 1a (Colton blood group), tandem duplicate 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (238 aa)
	ENSSDUP00000021538	Lysine (K)-specific demethylase 6B, b. (601 aa)
	park7	Parkinson protein 7. (189 aa)
	LOC111228668	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (447 aa)
	ripk1	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (682 aa)
	LOC111238592	Receptor-interacting serine-threonine kinase 3. (514 aa)
	aifm1	Apoptosis inducing factor mitochondrion associated 1. (721 aa)
	trpa1	Transient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family. (1101 aa)
	ENSSDUP00000013560	Cytochrome P450, family 1, subfamily C, polypeptide 2; Belongs to the cytochrome P450 family. (533 aa)
	ENSSDUP00000013550	Uncharacterized protein. (191 aa)
	LOC111225396	Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (525 aa)
	LOC111240229	Uncharacterized protein; Belongs to the cytochrome P450 family. (401 aa)
	fxn	Frataxin. (215 aa)
	edn1	Endothelin 1. (187 aa)
	LOC111220280	Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b. (428 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (612 aa)
	znf277	Zinc finger protein 277. (440 aa)
	kdm6b	Lysine (K)-specific demethylase 6B, a. (2290 aa)
	ect2	Epithelial cell transforming 2. (1129 aa)
	impact	Impact RWD domain protein. (323 aa)
	smpd3	Sphingomyelin phosphodiesterase 3, neutral. (694 aa)
	ENSSDUP00000026942	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (515 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (695 aa)

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111228668	LOC111238592	ENSSDUP00000019685	ENSSDUP00000019573	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Receptor-interacting serine-threonine kinase 3.	0.907
LOC111228668	ripk1	ENSSDUP00000019685	ENSSDUP00000027765	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.997
LOC111228668	tnfaip3	ENSSDUP00000019685	ENSSDUP00000025868	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Tumor necrosis factor, alpha-induced protein 3.	0.953
LOC111238592	LOC111228668	ENSSDUP00000019573	ENSSDUP00000019685	Receptor-interacting serine-threonine kinase 3.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.907
LOC111238592	ripk1	ENSSDUP00000019573	ENSSDUP00000027765	Receptor-interacting serine-threonine kinase 3.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.997
LOC111238592	tnfaip3	ENSSDUP00000019573	ENSSDUP00000025868	Receptor-interacting serine-threonine kinase 3.	Tumor necrosis factor, alpha-induced protein 3.	0.953
nfe2l2	sirt1	ENSSDUP00000000473	ENSSDUP00000024624	Nuclear factor, erythroid 2-like 2a.	Deacetylase sirtuin-type domain-containing protein.	0.430
ripk1	LOC111228668	ENSSDUP00000027765	ENSSDUP00000019685	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.997
ripk1	LOC111238592	ENSSDUP00000027765	ENSSDUP00000019573	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	Receptor-interacting serine-threonine kinase 3.	0.997
ripk1	tnfaip3	ENSSDUP00000027765	ENSSDUP00000025868	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	Tumor necrosis factor, alpha-induced protein 3.	0.981
sirt1	nfe2l2	ENSSDUP00000024624	ENSSDUP00000000473	Deacetylase sirtuin-type domain-containing protein.	Nuclear factor, erythroid 2-like 2a.	0.430
tnfaip3	LOC111228668	ENSSDUP00000025868	ENSSDUP00000019685	Tumor necrosis factor, alpha-induced protein 3.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.953
tnfaip3	LOC111238592	ENSSDUP00000025868	ENSSDUP00000019573	Tumor necrosis factor, alpha-induced protein 3.	Receptor-interacting serine-threonine kinase 3.	0.953
tnfaip3	ripk1	ENSSDUP00000025868	ENSSDUP00000027765	Tumor necrosis factor, alpha-induced protein 3.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.981