(26 nodes) Stem cell proliferation network (Seriola dumerili)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSDUP00000010765	Uncharacterized protein. (574 aa)
	bysl	Bystin-like. (436 aa)
	lig4	DNA ligase. (914 aa)
	ENSSDUP00000015520	BRCA2 DNA repair associated. (3048 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
	ETV6	ETS variant 6. (471 aa)
	ythdf2	YTH N(6)-methyladenosine RNA binding protein 2. (639 aa)
	arih2	RBR-type E3 ubiquitin transferase. (511 aa)
	kdf1	Keratinocyte differentiation factor 1a. (371 aa)
	xrcc5	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (726 aa)
	LOC111222303	RING-type domain-containing protein. (836 aa)
	znrf3	Zinc and ring finger 3. (894 aa)
	cdkn2c	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (164 aa)
	LOC111224124	Uncharacterized protein. (340 aa)
	LOC111228103	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (198 aa)
	LOC111216899	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	trim71	Tripartite motif containing 71, E3 ubiquitin protein ligase. (830 aa)
	LOC111230392	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
	ism1	Isthmin 1. (455 aa)
	mecom	MDS1 and EVI1 complex locus. (1051 aa)
	cep120	Centrosomal protein 120. (960 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	mettl3	Methyltransferase like 3; Belongs to the MT-A70-like family. (592 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (151 aa)
	Nf1	Uncharacterized protein. (620 aa)

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSDUP00000010765	ENSSDUP00000015520	ENSSDUP00000010765	ENSSDUP00000015520	Uncharacterized protein.	BRCA2 DNA repair associated.	0.436
ENSSDUP00000010765	Nf1	ENSSDUP00000010765	ENSSDUP00000010667	Uncharacterized protein.	Uncharacterized protein.	0.943
ENSSDUP00000015520	ENSSDUP00000010765	ENSSDUP00000015520	ENSSDUP00000010765	BRCA2 DNA repair associated.	Uncharacterized protein.	0.436
ENSSDUP00000015520	Nf1	ENSSDUP00000015520	ENSSDUP00000010667	BRCA2 DNA repair associated.	Uncharacterized protein.	0.436
ENSSDUP00000015520	ercc2	ENSSDUP00000015520	ENSSDUP00000003205	BRCA2 DNA repair associated.	Excision repair cross-complementation group 2.	0.649
ENSSDUP00000015520	lig4	ENSSDUP00000015520	ENSSDUP00000014199	BRCA2 DNA repair associated.	DNA ligase.	0.645
ENSSDUP00000015520	xrcc5	ENSSDUP00000015520	ENSSDUP00000023908	BRCA2 DNA repair associated.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.601
LOC111216899	fgf2	ENSSDUP00000001524	ENSSDUP00000010321	Transforming growth factor beta; Belongs to the TGF-beta family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.601
LOC111222303	znrf3	ENSSDUP00000024222	ENSSDUP00000024566	RING-type domain-containing protein.	Zinc and ring finger 3.	0.753
Nf1	ENSSDUP00000010765	ENSSDUP00000010667	ENSSDUP00000010765	Uncharacterized protein.	Uncharacterized protein.	0.943
Nf1	ENSSDUP00000015520	ENSSDUP00000010667	ENSSDUP00000015520	Uncharacterized protein.	BRCA2 DNA repair associated.	0.436
ercc2	ENSSDUP00000015520	ENSSDUP00000003205	ENSSDUP00000015520	Excision repair cross-complementation group 2.	BRCA2 DNA repair associated.	0.649
ercc2	lig4	ENSSDUP00000003205	ENSSDUP00000014199	Excision repair cross-complementation group 2.	DNA ligase.	0.627
ercc2	xrcc5	ENSSDUP00000003205	ENSSDUP00000023908	Excision repair cross-complementation group 2.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.592
fgf2	LOC111216899	ENSSDUP00000010321	ENSSDUP00000001524	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.601
lig4	ENSSDUP00000015520	ENSSDUP00000014199	ENSSDUP00000015520	DNA ligase.	BRCA2 DNA repair associated.	0.645
lig4	ercc2	ENSSDUP00000014199	ENSSDUP00000003205	DNA ligase.	Excision repair cross-complementation group 2.	0.627
lig4	xrcc5	ENSSDUP00000014199	ENSSDUP00000023908	DNA ligase.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.985
mettl3	ythdf2	ENSSDUP00000008329	ENSSDUP00000022443	Methyltransferase like 3; Belongs to the MT-A70-like family.	YTH N(6)-methyladenosine RNA binding protein 2.	0.580
xrcc5	ENSSDUP00000015520	ENSSDUP00000023908	ENSSDUP00000015520	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	BRCA2 DNA repair associated.	0.601