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exosc1 exosc1 nabp1 nabp1 lig3 lig3 LOC111220469 LOC111220469 mcm3 mcm3 spout1 spout1 LOC111220449 LOC111220449 LOC111220450 LOC111220450 ENSSDUP00000015520 ENSSDUP00000015520 carhsp1 carhsp1 helz2 helz2 psmc1 psmc1 LOC111240105 LOC111240105 polr2h polr2h LOC111233136 LOC111233136 psmc3 psmc3 rps11 rps11 PNPT1 PNPT1 rmi2 rmi2 ten1 ten1 EIF5AL1 EIF5AL1 psmc4 psmc4 ENSSDUP00000015967 ENSSDUP00000015967 ENSSDUP00000016000 ENSSDUP00000016000 rpa1 rpa1 nars1 nars1 mrps12 mrps12 YBX2 YBX2 ENSSDUP00000014379 ENSSDUP00000014379 psmc5 psmc5 pdcd11 pdcd11 lig1 lig1 mcm8 mcm8 ybx1 ybx1 rps23 rps23 mcm4 mcm4 mrps17 mrps17 dis3 dis3 mcm5 mcm5 psmc2 psmc2 dars1 dars1 rps28 rps28 rpa3 rpa3 eif1ad eif1ad nars2 nars2 mcm10 mcm10 polr3h polr3h radx radx CSDC2 CSDC2 polr2g polr2g pot1 pot1 CSDE1 CSDE1 exosc3 exosc3 ssbp1 ssbp1 RPA1 RPA1 kars1 kars1 ttc14 ttc14 supt6h supt6h lig4 lig4 rpl8 rpl8 yars1 yars1 aimp1 aimp1 LOC111239985 LOC111239985 ddias ddias dis3l dis3l dars2 dars2 LOC111238298 LOC111238298 mcm7 mcm7 mrpl2 mrpl2 shld2 shld2 eif2s1 eif2s1 rngtt rngtt ENSSDUP00000005865 ENSSDUP00000005865 LOC111238303 LOC111238303 mcm6 mcm6 exosc2 exosc2 stn1 stn1 dis3l2 dis3l2 meiob meiob psmc6 psmc6 LOC111236850 LOC111236850 lin28a lin28a rpa2 rpa2 mcm2 mcm2 ccar1 ccar1 zcchc17 zcchc17
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
exosc1Exosome component 1. (194 aa)
nabp1Nucleic acid binding protein 1a. (218 aa)
lig3DNA ligase. (1013 aa)
LOC111220469Cold shock domain containing C2, RNA binding a. (157 aa)
mcm3DNA helicase; Belongs to the MCM family. (815 aa)
spout1SPOUT domain containing methyltransferase 1. (380 aa)
LOC111220449DEAH (Asp-Glu-Ala-His) box polypeptide 8. (1222 aa)
LOC111220450DEAH (Asp-Glu-Ala-His) box polypeptide 8. (1192 aa)
ENSSDUP00000015520BRCA2 DNA repair associated. (3048 aa)
carhsp1Calcium regulated heat stable protein 1. (161 aa)
helz2Uncharacterized protein. (2900 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (455 aa)
LOC111240105tRNA-binding domain-containing protein. (316 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
LOC111233136Aminoacyl tRNA synthetase complex interacting multifunctional protein 1b. (322 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
rps11Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (210 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (770 aa)
rmi2RecQ mediated genome instability 2. (166 aa)
ten1TEN1 subunit of CST complex. (132 aa)
EIF5AL1Eukaryotic translation initiation factor 5A. (155 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (441 aa)
ENSSDUP00000015967Lin-28 homolog A (C. elegans). (178 aa)
ENSSDUP00000016000RPA_C domain-containing protein. (250 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
nars1Asparaginyl-tRNA synthetase. (558 aa)
mrps12Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family. (145 aa)
YBX2Y-box binding protein 2. (323 aa)
ENSSDUP00000014379eIF-5a domain-containing protein. (83 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
pdcd11Programmed cell death 11. (1574 aa)
lig1DNA ligase. (616 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (846 aa)
ybx1Y box binding protein 1. (302 aa)
rps23Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (143 aa)
mcm4DNA helicase; Belongs to the MCM family. (861 aa)
mrps17Mitochondrial ribosomal protein S17. (148 aa)
dis3DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (951 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
dars1Aspartyl-tRNA synthetase. (530 aa)
rps28Ribosomal protein S28. (53 aa)
rpa3Replication protein A3. (122 aa)
eif1adEukaryotic translation initiation factor 1A domain containing. (168 aa)
nars2Asparaginyl-tRNA synthetase 2, mitochondrial. (484 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (921 aa)
polr3hPolymerase (RNA) III (DNA directed) polypeptide H. (215 aa)
radxRPA1 related single stranded DNA binding protein. (848 aa)
CSDC2Cold shock domain containing C2. (155 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (188 aa)
pot1Protection of telomeres 1 homolog. (811 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (879 aa)
exosc3Exosome component 3. (244 aa)
ssbp1Single-stranded DNA binding protein 1. (147 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (680 aa)
kars1Lysine--tRNA ligase. (610 aa)
ttc14Tetratricopeptide repeat domain 14. (403 aa)
supt6hTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1675 aa)
lig4DNA ligase. (914 aa)
rpl8Ribosomal protein L8. (257 aa)
yars1Tyrosine--tRNA ligase. (530 aa)
aimp1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1a. (317 aa)
LOC111239985Uncharacterized protein. (605 aa)
ddiasRep_fac-A_C domain-containing protein. (854 aa)
dis3lDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1049 aa)
dars2Aspartyl-tRNA synthetase 2, mitochondrial. (661 aa)
LOC111238298Eukaryotic translation initiation factor 5A. (156 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
mrpl2Mitochondrial ribosomal protein L2. (297 aa)
shld2Si:ch211-134m17.9. (770 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha b. (330 aa)
rngttPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (601 aa)
ENSSDUP00000005865Uncharacterized protein. (2165 aa)
LOC111238303Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
mcm6DNA helicase; Belongs to the MCM family. (815 aa)
exosc2Exosome component 2. (294 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (365 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1074 aa)
meiobMethionine sulfoxide reductase B1b. (472 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
LOC111236850Lin-28 homolog B (C. elegans). (231 aa)
lin28aLin-28 homolog A. (195 aa)
rpa2Replication protein A2. (278 aa)
mcm2DNA helicase; Belongs to the MCM family. (888 aa)
ccar1Cell division cycle and apoptosis regulator 1. (1250 aa)
zcchc17Zinc finger, CCHC domain containing 17. (251 aa)
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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