11 items (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111233774	Uncharacterized protein. (193 aa)
	LOC111222939	Ras homolog gene family, member Ab. (246 aa)
	LOC111218955	Uncharacterized protein. (199 aa)
	LOC111218956	Uncharacterized protein. (193 aa)
	LOC111230710	Uncharacterized protein. (193 aa)
	rock1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1364 aa)
	cfl1	Cofilin 1; Belongs to the actin-binding proteins ADF family. (167 aa)
	LOC111219488	Ras homolog family member Ca. (193 aa)
	rock2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1398 aa)
	LOC111237172	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
	RHOB	Ras homolog family member B. (143 aa)

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111218955	rock1	ENSSDUP00000019735	ENSSDUP00000022961	Uncharacterized protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.737
LOC111218955	rock2	ENSSDUP00000019735	ENSSDUP00000025185	Uncharacterized protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.737
LOC111218956	rock1	ENSSDUP00000021075	ENSSDUP00000022961	Uncharacterized protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.972
LOC111218956	rock2	ENSSDUP00000021075	ENSSDUP00000025185	Uncharacterized protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.972
LOC111219488	rock1	ENSSDUP00000029821	ENSSDUP00000022961	Ras homolog family member Ca.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.737
LOC111219488	rock2	ENSSDUP00000029821	ENSSDUP00000025185	Ras homolog family member Ca.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.737
LOC111222939	rock1	ENSSDUP00000018265	ENSSDUP00000022961	Ras homolog gene family, member Ab.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.972
LOC111222939	rock2	ENSSDUP00000018265	ENSSDUP00000025185	Ras homolog gene family, member Ab.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.972
LOC111230710	rock1	ENSSDUP00000022926	ENSSDUP00000022961	Uncharacterized protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.972
LOC111230710	rock2	ENSSDUP00000022926	ENSSDUP00000025185	Uncharacterized protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.972
LOC111233774	rock1	ENSSDUP00000002943	ENSSDUP00000022961	Uncharacterized protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.972
LOC111233774	rock2	ENSSDUP00000002943	ENSSDUP00000025185	Uncharacterized protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.972
LOC111237172	cfl1	ENSSDUP00000000683	ENSSDUP00000024937	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.	Cofilin 1; Belongs to the actin-binding proteins ADF family.	0.901
RHOB	rock1	ENSSDUP00000002301	ENSSDUP00000022961	Ras homolog family member B.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.737
RHOB	rock2	ENSSDUP00000002301	ENSSDUP00000025185	Ras homolog family member B.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.737
cfl1	LOC111237172	ENSSDUP00000024937	ENSSDUP00000000683	Cofilin 1; Belongs to the actin-binding proteins ADF family.	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.	0.901
rock1	LOC111218955	ENSSDUP00000022961	ENSSDUP00000019735	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Uncharacterized protein.	0.737
rock1	LOC111218956	ENSSDUP00000022961	ENSSDUP00000021075	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Uncharacterized protein.	0.972
rock1	LOC111219488	ENSSDUP00000022961	ENSSDUP00000029821	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Ras homolog family member Ca.	0.737
rock1	LOC111222939	ENSSDUP00000022961	ENSSDUP00000018265	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Ras homolog gene family, member Ab.	0.972