STRINGSTRING
LOC111237588 LOC111237588 flrt2 flrt2 ppp2r1b ppp2r1b cbl cbl ppp2ca ppp2ca gab1 gab1 SPRED2 SPRED2 LOC111232356 LOC111232356 LOC111234449 LOC111234449 hras hras fgf5 fgf5 kras kras grb2 grb2 LOC111233537 LOC111233537 LOC111230220 LOC111230220 plcg1 plcg1 LOC111232673 LOC111232673 ubc ubc LOC111220642 LOC111220642 LOC111217085 LOC111217085 LOC111236831 LOC111236831 LOC111232662 LOC111232662 fgf2 fgf2 mknk1 mknk1 ubb ubb LOC111239474 LOC111239474 LOC111226537 LOC111226537 shc1 shc1 LOC111226526 LOC111226526 LOC111235128 LOC111235128 fgf22 fgf22 ANOS1 ANOS1 rps27a rps27a LOC111232634 LOC111232634 flrt3 flrt3 LOC111230392 LOC111230392 LOC111233755 LOC111233755 FGFRL1 FGFRL1 LOC111228103 LOC111228103 FGF6 FGF6 fgf23 fgf23 LOC111228886 LOC111228886 fgf17 fgf17 LOC111229366 LOC111229366 LOC111233334 LOC111233334 mknk2 mknk2 fndc3b fndc3b LOC111222720 LOC111222720 LOC111216523 LOC111216523 LOC111226673 LOC111226673 fgf3 fgf3 fgf4 fgf4 ppp2cb ppp2cb fndc3a fndc3a LOC111228782 LOC111228782 spred1 spred1 CSDE1 CSDE1 pik3ca pik3ca LOC111222298 LOC111222298 SHC4 SHC4 LOC111230214 LOC111230214 ENSSDUP00000022655 ENSSDUP00000022655 LOC111222925 LOC111222925 LOC111239442 LOC111239442 LOC111226155 LOC111226155 fgf10 fgf10 FGF6-2 FGF6-2 LOC111236039 LOC111236039 LOC111236845 LOC111236845 uba52 uba52
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111237588Sprouty related EVH1 domain containing 2a. (425 aa)
flrt2Fibronectin leucine rich transmembrane protein 2. (670 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (636 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (956 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
gab1GRB2-associated binding protein 1. (758 aa)
SPRED2Sprouty related EVH1 domain containing 2. (465 aa)
LOC111232356Anosmin 1a. (627 aa)
LOC111234449Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC111233537Tyrosine-protein kinase. (550 aa)
LOC111230220Zgc:55558. (187 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1289 aa)
LOC111232673Fibronectin leucine rich transmembrane protein 1b. (702 aa)
ubcUncharacterized protein. (748 aa)
LOC111220642Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
LOC111217085Uncharacterized protein. (867 aa)
LOC111236831Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC111232662Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (151 aa)
mknk1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (463 aa)
ubbUncharacterized protein. (153 aa)
LOC111239474Fibronectin leucine rich transmembrane protein 2. (660 aa)
LOC111226537Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (158 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (517 aa)
LOC111226526Serine/threonine-protein phosphatase. (309 aa)
LOC111235128Tyrosine-protein kinase. (543 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
ANOS1Anosmin 1. (673 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC111232634Fibroblast growth factor receptor like 1a. (501 aa)
flrt3Fibronectin leucine rich transmembrane 3. (650 aa)
LOC111230392Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
LOC111233755Fibroblast growth factor receptor substrate 2b. (550 aa)
FGFRL1Fibroblast growth factor receptor like 1. (505 aa)
LOC111228103Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (198 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (197 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (261 aa)
LOC111228886Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1073 aa)
fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
LOC111229366Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (227 aa)
LOC111233334PH domain-containing protein. (770 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
fndc3bFibronectin type III domain containing 3Ba. (1210 aa)
LOC111222720Sprouty RTK signaling antagonist 2. (353 aa)
LOC111216523Uncharacterized protein. (720 aa)
LOC111226673Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
fndc3aFibronectin type III domain containing 3A. (1241 aa)
LOC111228782Ubiquitin A-52 residue ribosomal protein fusion product 1. (132 aa)
spred1Sprouty related EVH1 domain containing 1. (457 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (879 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC111222298Fibronectin leucine rich transmembrane protein 1. (685 aa)
SHC4SHC adaptor protein 4. (533 aa)
LOC111230214Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
ENSSDUP00000022655Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (191 aa)
LOC111222925Fibroblast growth factor receptor substrate 3. (615 aa)
LOC111239442Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (196 aa)
LOC111226155Fibroblast growth factor receptor. (831 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (184 aa)
LOC111236039Cbl proto-oncogene C, E3 ubiquitin protein ligase. (596 aa)
LOC111236845Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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