STRINGSTRING
mcm4 mcm4 prim2 prim2 ENSSDUP00000032464 ENSSDUP00000032464 ENSSDUP00000032462 ENSSDUP00000032462 rfc2 rfc2 kpnb1 kpnb1 ENSSDUP00000022454 ENSSDUP00000022454 RPA1 RPA1 ENSSDUP00000022496 ENSSDUP00000022496 ENSSDUP00000022505 ENSSDUP00000022505 kpna1 kpna1 LOC111220098 LOC111220098 ubc ubc pold1 pold1 psmc2 psmc2 rfc5 rfc5 mcm5 mcm5 LOC111223275 LOC111223275 orc3 orc3 LOC111230957 LOC111230957 fen1 fen1 ube2c ube2c anapc16 anapc16 orc5 orc5 anapc1 anapc1 psmb7 psmb7 psmd13 psmd13 LOC111227991 LOC111227991 ENSSDUP00000027664 ENSSDUP00000027664 gins2 gins2 pole3 pole3 ENSSDUP00000027840 ENSSDUP00000027840 prim1 prim1 dna2 dna2 rbx1 rbx1 ENSSDUP00000000054 ENSSDUP00000000054 ENSSDUP00000000081 ENSSDUP00000000081 anapc5 anapc5 ENSSDUP00000027851 ENSSDUP00000027851 ENSSDUP00000028071 ENSSDUP00000028071 psme1 psme1 psmd14 psmd14 LOC111217160 LOC111217160 LOC111222397 LOC111222397 gins4 gins4 skp1 skp1 psma8 psma8 psmb2 psmb2 psmd9 psmd9 skp2 skp2 mcm8 mcm8 lig1 lig1 psmd8 psmd8 LOC111237550 LOC111237550 ENSSDUP00000029566 ENSSDUP00000029566 LOC111222185 LOC111222185 LOC111221130 LOC111221130 ENSSDUP00000029876 ENSSDUP00000029876 pold2 pold2 cdc26 cdc26 psmd6 psmd6 rfc1 rfc1 psmb8 psmb8 LOC111239428 LOC111239428 LOC111239429 LOC111239429 LOC111239430 LOC111239430 psmc5 psmc5 rfc4 rfc4 bicra bicra ENSSDUP00000000304 ENSSDUP00000000304 ENSSDUP00000000428 ENSSDUP00000000428 psma3 psma3 LOC111237687 LOC111237687 anapc4 anapc4 anapc15 anapc15 psmc3 psmc3 psmb1 psmb1 ENSSDUP00000000783 ENSSDUP00000000783 ENSSDUP00000001025 ENSSDUP00000001025 ENSSDUP00000001040 ENSSDUP00000001040 PSMA4 PSMA4 LOC111227553 LOC111227553 ENSSDUP00000001176 ENSSDUP00000001176 ENSSDUP00000001199 ENSSDUP00000001199 psmc6 psmc6 Mcm9 Mcm9 cdc6 cdc6 orc1 orc1 psma1 psma1 kpna6 kpna6 orc2 orc2 psma5 psma5 psmb4 psmb4 dbf4 dbf4 atad5 atad5 LOC111237191 LOC111237191 LOC111220419 LOC111220419 gins3 gins3 H2AZ1 H2AZ1 pola1 pola1 cdc45 cdc45 pcna pcna rps27a rps27a cul1 cul1 mcm7 mcm7 gins1 gins1 anapc11 anapc11 cdk2 cdk2 anapc7 anapc7 psmb3 psmb3 kpna5 kpna5 mcm6 mcm6 ENSSDUP00000006945 ENSSDUP00000006945 ENSSDUP00000006989 ENSSDUP00000006989 LOC111221313 LOC111221313 psmd1 psmd1 fam89a fam89a ENSSDUP00000007129 ENSSDUP00000007129 ENSSDUP00000007300 ENSSDUP00000007300 ENSSDUP00000007804 ENSSDUP00000007804 anapc2 anapc2 meiob meiob pold4 pold4 PSMD11 PSMD11 LOC111237983 LOC111237983 psmc1 psmc1 psme4 psme4 cdc23 cdc23 ubb ubb LOC111228884 LOC111228884 RCBTB1 RCBTB1 mcm3 mcm3 ccna2 ccna2 ube2s ube2s CCNE2 CCNE2 mcm2 mcm2 psmd2 psmd2 psmf1 psmf1 cdc16 cdc16 rpa2 rpa2 pold3 pold3 ENSSDUP00000013391 ENSSDUP00000013391 uba52 uba52 ENSSDUP00000014088 ENSSDUP00000014088 pole4 pole4 LOC111219851 LOC111219851 LOC111232868 LOC111232868 LOC111232869 LOC111232869 LOC111232798 LOC111232798 ENSSDUP00000014654 ENSSDUP00000014654 psme2 psme2 psme3 psme3 psmd10 psmd10 LOC111228832 LOC111228832 gmnn gmnn ccne1 ccne1 psmd12 psmd12 anapc10 anapc10 cdc7 cdc7 LOC111236888 LOC111236888 LOC111236900 LOC111236900 LOC111230559 LOC111230559 psmc4 psmc4 psma2 psma2 ENSSDUP00000016000 ENSSDUP00000016000 LOC111223824 LOC111223824 ENSSDUP00000016099 ENSSDUP00000016099 rpa1 rpa1 LOC111219765 LOC111219765 ENSSDUP00000017647 ENSSDUP00000017647 ENSSDUP00000017713 ENSSDUP00000017713 rcbtb2 rcbtb2 rpa3 rpa3 ENSSDUP00000017929 ENSSDUP00000017929 LOC111221389 LOC111221389 pole pole orc4 orc4 LOC111228782 LOC111228782 ENSSDUP00000018517 ENSSDUP00000018517 ENSSDUP00000018600 ENSSDUP00000018600 ENSSDUP00000018672 ENSSDUP00000018672 LOC111219593 LOC111219593 ENSSDUP00000018777 ENSSDUP00000018777 LOC111239148 LOC111239148 ccna1 ccna1 rfc3 rfc3 mcm10 mcm10 psmd5 psmd5 LOC111234108 LOC111234108 ENSSDUP00000021373 ENSSDUP00000021373 ENSSDUP00000021478 ENSSDUP00000021478 pole2 pole2 psmd7 psmd7 LOC111221050 LOC111221050 psmd3 psmd3 ENSSDUP00000021685 ENSSDUP00000021685 ENSSDUP00000021729 ENSSDUP00000021729 tm7sf3 tm7sf3 FZR1 FZR1 ENSSDUP00000021879 ENSSDUP00000021879 cdt1 cdt1 ENSSDUP00000021971 ENSSDUP00000021971 ENSSDUP00000022019 ENSSDUP00000022019 pola2 pola2 kxd1 kxd1 ENSSDUP00000022246 ENSSDUP00000022246 ENSSDUP00000022255 ENSSDUP00000022255 cdc27 cdc27 LOC111229617 LOC111229617
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mcm4DNA helicase; Belongs to the MCM family. (861 aa)
prim2DNA primase subunit 2. (592 aa)
ENSSDUP00000032464Histone H2A; Belongs to the histone H2A family. (127 aa)
ENSSDUP00000032462Histone H2A; Belongs to the histone H2A family. (126 aa)
rfc2Replication factor C (activator 1) 2. (387 aa)
kpnb1Karyopherin (importin) beta 1. (876 aa)
ENSSDUP00000022454Histone H3; Belongs to the histone H3 family. (121 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (680 aa)
ENSSDUP00000022496Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa)
ENSSDUP00000022505Histone domain-containing protein; Belongs to the histone H2B family. (121 aa)
kpna1Importin subunit alpha; Belongs to the importin alpha family. (543 aa)
LOC111220098Proteasome activator subunit 4b. (1764 aa)
ubcUncharacterized protein. (748 aa)
pold1DNA polymerase. (1121 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
LOC111223275Proteasome 26S subunit, non-ATPase 4a. (372 aa)
orc3Origin recognition complex, subunit 3. (722 aa)
LOC111230957Histone H2B; Belongs to the histone H2B family. (124 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
anapc16Anaphase promoting complex subunit 16. (108 aa)
orc5Origin recognition complex, subunit 5. (445 aa)
anapc1Anaphase promoting complex subunit 1. (1978 aa)
psmb7Proteasome subunit beta. (277 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (392 aa)
LOC111227991Histone H2A; Belongs to the histone H2A family. (165 aa)
ENSSDUP00000027664Histone_H2A_C domain-containing protein. (155 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (146 aa)
ENSSDUP00000027840Uncharacterized protein; Belongs to the histone H2B family. (117 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (423 aa)
dna2DNA replication helicase/nuclease 2. (1406 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
ENSSDUP00000000054Histone H2B; Belongs to the histone H2B family. (131 aa)
ENSSDUP00000000081Histone H2A; Belongs to the histone H2A family. (142 aa)
anapc5Anaphase promoting complex subunit 5. (773 aa)
ENSSDUP00000027851Uncharacterized protein. (80 aa)
ENSSDUP00000028071Proteasome subunit beta. (274 aa)
psme1Proteasome activator subunit 1. (255 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
LOC111217160Family with sequence similarity 89 member B. (170 aa)
LOC111222397Histone H3.3. (136 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (226 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (164 aa)
psma8Proteasome subunit alpha type. (296 aa)
psmb2Proteasome subunit beta. (199 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (212 aa)
skp2S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (437 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (846 aa)
lig1DNA ligase. (616 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (290 aa)
LOC111237550Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa)
ENSSDUP00000029566Histone H2B; Belongs to the histone H2B family. (114 aa)
LOC111222185Histone H2A; Belongs to the histone H2A family. (140 aa)
LOC111221130Proteasome subunit beta. (278 aa)
ENSSDUP00000029876Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (491 aa)
cdc26Cell division cycle 26 homolog. (97 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
rfc1Replication factor C subunit 1. (1181 aa)
psmb8Proteasome subunit beta. (276 aa)
LOC111239428Proteasome subunit beta. (275 aa)
LOC111239429Proteasome subunit beta 12. (217 aa)
LOC111239430Proteasome subunit beta. (216 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
rfc4Replication factor C (activator 1) 4. (359 aa)
bicraBRD4 interacting chromatin remodeling complex associated protein. (1788 aa)
ENSSDUP00000000304Histone H3; Belongs to the histone H3 family. (108 aa)
ENSSDUP00000000428Uncharacterized protein. (115 aa)
psma3Proteasome subunit alpha type. (255 aa)
LOC111237687ATPase family AAA domain containing 5b. (887 aa)
anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (780 aa)
anapc15Anaphase promoting complex subunit 15. (122 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
psmb1Proteasome subunit beta. (237 aa)
ENSSDUP00000000783Histone H2A; Belongs to the histone H2A family. (143 aa)
ENSSDUP00000001025Histone H2B; Belongs to the histone H2B family. (116 aa)
ENSSDUP00000001040Uncharacterized protein; Belongs to the histone H2B family. (67 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
LOC111227553WD_REPEATS_REGION domain-containing protein. (495 aa)
ENSSDUP00000001176Histone H3; Belongs to the histone H3 family. (110 aa)
ENSSDUP00000001199Histone H2A; Belongs to the histone H2A family. (133 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
Mcm9Uncharacterized protein. (108 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (571 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (832 aa)
psma1Proteasome subunit alpha type. (266 aa)
kpna6Importin subunit alpha; Belongs to the importin alpha family. (547 aa)
orc2Origin recognition complex, subunit 2. (594 aa)
psma5Proteasome subunit alpha type. (241 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
dbf4DBF4 zinc finger. (626 aa)
atad5ATPase family AAA domain containing 5a. (1852 aa)
LOC111237191Proteasome 26S subunit, non-ATPase 4b. (375 aa)
LOC111220419Histone H3; Belongs to the histone H3 family. (136 aa)
gins3GINS complex subunit 3. (211 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (154 aa)
pola1DNA polymerase. (1474 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (576 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
rps27aRibosomal protein S27a. (156 aa)
cul1Cullin 1b; Belongs to the cullin family. (776 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
gins1GINS complex subunit 1 (Psf1 homolog). (196 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
psmb3Proteasome subunit beta. (205 aa)
kpna5Importin subunit alpha; Belongs to the importin alpha family. (536 aa)
mcm6DNA helicase; Belongs to the MCM family. (815 aa)
ENSSDUP00000006945Uncharacterized protein. (267 aa)
ENSSDUP00000006989Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC111221313Histone H2B; Belongs to the histone H2B family. (123 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa)
fam89aFamily with sequence similarity 89 member A. (180 aa)
ENSSDUP00000007129Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
ENSSDUP00000007300Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (90 aa)
ENSSDUP00000007804Histone H2A; Belongs to the histone H2A family. (130 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (818 aa)
meiobMethionine sulfoxide reductase B1b. (472 aa)
pold4Si:dkey-28b4.7. (108 aa)
PSMD11PCI domain-containing protein. (422 aa)
LOC111237983Proteasome subunit alpha type. (246 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (455 aa)
psme4Proteasome activator subunit 4a. (1762 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
ubbUncharacterized protein. (153 aa)
LOC111228884Fizzy/cell division cycle 20 related 1b. (519 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
mcm3DNA helicase; Belongs to the MCM family. (815 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (437 aa)
ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (237 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (409 aa)
mcm2DNA helicase; Belongs to the MCM family. (888 aa)
psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (906 aa)
psmf1Proteasome inhibitor subunit 1. (277 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (619 aa)
rpa2Replication protein A2. (278 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (439 aa)
ENSSDUP00000013391Histone H2A; Belongs to the histone H2A family. (134 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
ENSSDUP00000014088SCY domain-containing protein. (120 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)
LOC111219851Proteasome 26S subunit, non-ATPase 11b. (422 aa)
LOC111232868Histone H3.3. (136 aa)
LOC111232869Histone H3.3. (136 aa)
LOC111232798Proteasome subunit alpha type. (246 aa)
ENSSDUP00000014654Histone H2A; Belongs to the histone H2A family. (126 aa)
psme2Proteasome activator subunit 2. (255 aa)
psme3Proteasome activator subunit 3. (256 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
LOC111228832Zgc:110269. (344 aa)
gmnnGeminin DNA replication inhibitor. (215 aa)
ccne1Cyclin E1; Belongs to the cyclin family. (435 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (456 aa)
anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (206 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae); Belongs to the protein kinase superfamily. (472 aa)
LOC111236888Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
LOC111236900UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
LOC111230559UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (206 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (441 aa)
psma2Proteasome subunit alpha type. (234 aa)
ENSSDUP00000016000RPA_C domain-containing protein. (250 aa)
LOC111223824Proteasome subunit beta. (317 aa)
ENSSDUP00000016099Proteasome subunit beta. (303 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
LOC111219765Histone domain-containing protein. (107 aa)
ENSSDUP00000017647Histone H2B; Belongs to the histone H2B family. (139 aa)
ENSSDUP00000017713annotation not available (93 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
rpa3Replication protein A3. (122 aa)
ENSSDUP00000017929Histone H3; Belongs to the histone H3 family. (130 aa)
LOC111221389Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2076 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (457 aa)
LOC111228782Ubiquitin A-52 residue ribosomal protein fusion product 1. (132 aa)
ENSSDUP00000018517Histone H2A; Belongs to the histone H2A family. (140 aa)
ENSSDUP00000018600Histone H2B; Belongs to the histone H2B family. (114 aa)
ENSSDUP00000018672Histone H3; Belongs to the histone H3 family. (101 aa)
LOC111219593BRD4 interacting chromatin remodeling complex associated protein like. (823 aa)
ENSSDUP00000018777Histone H2A; Belongs to the histone H2A family. (134 aa)
LOC111239148Proteasome subunit beta. (233 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (410 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (921 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (504 aa)
LOC111234108Cyclin E2; Belongs to the cyclin family. (396 aa)
ENSSDUP00000021373Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
ENSSDUP00000021478Histone H2B; Belongs to the histone H2B family. (116 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (526 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (330 aa)
LOC111221050Histone H2A; Belongs to the histone H2A family. (136 aa)
psmd3Proteasome 26S subunit, non-ATPase 3. (519 aa)
ENSSDUP00000021685Histone H3; Belongs to the histone H3 family. (116 aa)
ENSSDUP00000021729Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa)
tm7sf3Transmembrane 7 superfamily member 3. (553 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (579 aa)
ENSSDUP00000021879Histone H2A; Belongs to the histone H2A family. (129 aa)
cdt1Chromatin licensing and DNA replication factor 1. (534 aa)
ENSSDUP00000021971Histone H3; Belongs to the histone H3 family. (96 aa)
ENSSDUP00000022019Histone domain-containing protein; Belongs to the histone H2B family. (116 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa)
kxd1KxDL motif containing 1. (184 aa)
ENSSDUP00000022246Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
ENSSDUP00000022255Histone H2A; Belongs to the histone H2A family. (139 aa)
cdc27Cell division cycle 27. (803 aa)
LOC111229617Proteasome subunit alpha type. (261 aa)
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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