74 items (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111221651	Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (530 aa)
	TGFB1I1	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (466 aa)
	cdkn1b	Cyclin-dependent kinase inhibitor 1Bb. (185 aa)
	khdrbs2	KH domain containing, RNA binding, signal transduction associated 2. (343 aa)
	LOC111239887	Betacellulin, epidermal growth factor family member. (187 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (879 aa)
	egfr	Receptor protein-tyrosine kinase. (1196 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	rasa1	RAS p21 protein activator (GTPase activating protein) 1a. (1049 aa)
	LOC111237405	Receptor protein-tyrosine kinase. (1182 aa)
	ubc	Uncharacterized protein. (748 aa)
	LOC111230220	Zgc:55558. (187 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	LOC111235389	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	LOC111234824	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (293 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (956 aa)
	LOC111221098	Neuregulin 1. (605 aa)
	LOC111231357	Docking protein 1b. (684 aa)
	elmod3	ELMO/CED-12 domain containing 3. (412 aa)
	LOC111233089	Uncharacterized protein. (318 aa)
	nono	Non-POU domain containing, octamer-binding. (441 aa)
	LOC111225174	Engulfment and cell motility 3. (715 aa)
	ENSSDUP00000030774	EGF-like domain-containing protein. (95 aa)
	LOC111233771	Receptor protein-tyrosine kinase. (1238 aa)
	erbb2	Receptor protein-tyrosine kinase. (1292 aa)
	elmod2	ELMO/CED-12 domain containing 2. (298 aa)
	gpnmb	Glycoprotein (transmembrane) nmb. (622 aa)
	arhgap35	Rho GTPase activating protein 35a. (1571 aa)
	LOC111234371	Neuregulin 2a. (602 aa)
	CDK4	Cyclin dependent kinase 4. (151 aa)
	cdk4	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (306 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2405 aa)
	cdk2	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC111221481	Engulfment and cell motility 2. (723 aa)
	LOC111232019	SH2 domain-containing protein. (427 aa)
	LOC111224096	Crystallin, beta B1, like 3; Belongs to the beta/gamma-crystallin family. (209 aa)
	egf	Epidermal growth factor. (1051 aa)
	ptpn1	Tyrosine-protein phosphatase non-receptor type. (437 aa)
	LOC111233200	KH domain containing, RNA binding, signal transduction associated 1b. (362 aa)
	LOC111227470	Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (527 aa)
	LOC111238251	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	khdrbs3	KH RNA binding domain containing, signal transduction associated 3. (370 aa)
	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1620 aa)
	LOC111238220	CRK proto-oncogene, adaptor protein. (315 aa)
	ubb	Uncharacterized protein. (153 aa)
	LOC111235000	Tyrosine-protein kinase. (516 aa)
	ENSSDUP00000009820	Protein kinase domain-containing protein. (180 aa)
	ENSSDUP00000009829	Uncharacterized protein. (226 aa)
	elmod1	ELMO/CED-12 domain containing 1. (325 aa)
	erbb3	Protein kinase domain-containing protein. (1353 aa)
	sfpq	Splicing factor proline/glutamine-rich. (641 aa)
	LOC111223159	Engulfment and cell motility 1. (726 aa)
	LOC111232203	Leupaxin. (399 aa)
	LOC111226747	Heparin-binding EGF-like growth factor a. (238 aa)
	LOC111217085	Uncharacterized protein. (867 aa)
	LOC111236039	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (596 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	nrg4	EGF-like domain-containing protein. (109 aa)
	pspc1	Paraspeckle component 1. (540 aa)
	LOC111225541	KH domain containing, RNA binding, signal transduction associated 1a. (400 aa)
	ccne1	Cyclin E1; Belongs to the cyclin family. (435 aa)
	LOC111227252	Suppressor of cytokine signaling 3a. (205 aa)
	ccnd1	Cyclin D1; Belongs to the cyclin family. (292 aa)
	nrg2	Neuregulin 2b. (696 aa)
	LOC111219064	Erb-b2 receptor tyrosine kinase 3b. (1370 aa)
	LOC111234595	Rho GTPase activating protein 35b. (1529 aa)
	rnf222	RING-type domain-containing protein. (197 aa)
	LOC111228782	Ubiquitin A-52 residue ribosomal protein fusion product 1. (132 aa)
	LOC111220086	Suppressor of cytokine signaling 3. (228 aa)
	ENSSDUP00000019408	EGF-like domain-containing protein. (105 aa)
	LOC111218871	Receptor protein-tyrosine kinase. (1379 aa)
	LOC111229077	Signal transducing adaptor family member 2a. (364 aa)

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDK4	LOC111228782	ENSSDUP00000006599	ENSSDUP00000018383	Cyclin dependent kinase 4.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.539
CDK4	LOC111234824	ENSSDUP00000006599	ENSSDUP00000028608	Cyclin dependent kinase 4.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.820
CDK4	ccnd1	ENSSDUP00000006599	ENSSDUP00000017296	Cyclin dependent kinase 4.	Cyclin D1; Belongs to the cyclin family.	0.820
CDK4	ccne1	ENSSDUP00000006599	ENSSDUP00000015399	Cyclin dependent kinase 4.	Cyclin E1; Belongs to the cyclin family.	0.770
CDK4	cdkn1b	ENSSDUP00000006599	ENSSDUP00000032511	Cyclin dependent kinase 4.	Cyclin-dependent kinase inhibitor 1Bb.	0.662
CDK4	rps27a	ENSSDUP00000006599	ENSSDUP00000004225	Cyclin dependent kinase 4.	Ribosomal protein S27a.	0.633
CDK4	uba52	ENSSDUP00000006599	ENSSDUP00000013443	Cyclin dependent kinase 4.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.539
CDK4	ubb	ENSSDUP00000006599	ENSSDUP00000009754	Cyclin dependent kinase 4.	Uncharacterized protein.	0.528
CDK4	ubc	ENSSDUP00000006599	ENSSDUP00000023286	Cyclin dependent kinase 4.	Uncharacterized protein.	0.528
CSDE1	ENSSDUP00000009820	ENSSDUP00000021333	ENSSDUP00000009820	Cold shock domain containing E1, RNA-binding.	Protein kinase domain-containing protein.	0.425
CSDE1	ENSSDUP00000009829	ENSSDUP00000021333	ENSSDUP00000009829	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.425
CSDE1	LOC111218871	ENSSDUP00000021333	ENSSDUP00000019789	Cold shock domain containing E1, RNA-binding.	Receptor protein-tyrosine kinase.	0.529
CSDE1	LOC111219064	ENSSDUP00000021333	ENSSDUP00000018046	Cold shock domain containing E1, RNA-binding.	Erb-b2 receptor tyrosine kinase 3b.	0.529
CSDE1	LOC111221098	ENSSDUP00000021333	ENSSDUP00000029112	Cold shock domain containing E1, RNA-binding.	Neuregulin 1.	0.401
CSDE1	LOC111226747	ENSSDUP00000021333	ENSSDUP00000012229	Cold shock domain containing E1, RNA-binding.	Heparin-binding EGF-like growth factor a.	0.428
CSDE1	LOC111228782	ENSSDUP00000021333	ENSSDUP00000018383	Cold shock domain containing E1, RNA-binding.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.438
CSDE1	LOC111233771	ENSSDUP00000021333	ENSSDUP00000030994	Cold shock domain containing E1, RNA-binding.	Receptor protein-tyrosine kinase.	0.529
CSDE1	LOC111234371	ENSSDUP00000021333	ENSSDUP00000007104	Cold shock domain containing E1, RNA-binding.	Neuregulin 2a.	0.401
CSDE1	LOC111234595	ENSSDUP00000021333	ENSSDUP00000018179	Cold shock domain containing E1, RNA-binding.	Rho GTPase activating protein 35b.	0.420
CSDE1	LOC111235000	ENSSDUP00000021333	ENSSDUP00000009758	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.425