15 items (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111226679	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (319 aa)
	LOC111237172	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
	dstn	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (200 aa)
	LOC111227308	Uncharacterized protein. (711 aa)
	il10	Interleukin 10. (187 aa)
	LOC111232050	Interleukin 12 receptor, beta 2a. (765 aa)
	LOC111223632	BolA family member 2; Belongs to the BolA/IbaG family. (86 aa)
	p4hb	Protein disulfide-isomerase. (517 aa)
	jak1	Tyrosine-protein kinase. (1155 aa)
	jak2	Tyrosine-protein kinase. (1133 aa)
	LOC111216626	Protein disulfide-isomerase. (577 aa)
	cfl1	Cofilin 1; Belongs to the actin-binding proteins ADF family. (167 aa)
	IL12B	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (320 aa)
	LOC111236541	Uncharacterized protein. (884 aa)
	LOC111236466	Tyrosine-protein kinase. (1114 aa)

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL12B	LOC111232050	ENSSDUP00000027855	ENSSDUP00000003206	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	Interleukin 12 receptor, beta 2a.	0.905
LOC111226679	il10	ENSSDUP00000013910	ENSSDUP00000003040	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	Interleukin 10.	0.430
LOC111232050	IL12B	ENSSDUP00000003206	ENSSDUP00000027855	Interleukin 12 receptor, beta 2a.	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	0.905
LOC111232050	LOC111236466	ENSSDUP00000003206	ENSSDUP00000032116	Interleukin 12 receptor, beta 2a.	Tyrosine-protein kinase.	0.573
LOC111232050	jak1	ENSSDUP00000003206	ENSSDUP00000017855	Interleukin 12 receptor, beta 2a.	Tyrosine-protein kinase.	0.573
LOC111232050	jak2	ENSSDUP00000003206	ENSSDUP00000022125	Interleukin 12 receptor, beta 2a.	Tyrosine-protein kinase.	0.742
LOC111236466	LOC111232050	ENSSDUP00000032116	ENSSDUP00000003206	Tyrosine-protein kinase.	Interleukin 12 receptor, beta 2a.	0.573
LOC111236466	jak1	ENSSDUP00000032116	ENSSDUP00000017855	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.937
LOC111236466	jak2	ENSSDUP00000032116	ENSSDUP00000022125	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.901
LOC111237172	cfl1	ENSSDUP00000000683	ENSSDUP00000024937	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.	Cofilin 1; Belongs to the actin-binding proteins ADF family.	0.901
LOC111237172	dstn	ENSSDUP00000000683	ENSSDUP00000002145	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.905
cfl1	LOC111237172	ENSSDUP00000024937	ENSSDUP00000000683	Cofilin 1; Belongs to the actin-binding proteins ADF family.	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.	0.901
cfl1	dstn	ENSSDUP00000024937	ENSSDUP00000002145	Cofilin 1; Belongs to the actin-binding proteins ADF family.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.905
dstn	LOC111237172	ENSSDUP00000002145	ENSSDUP00000000683	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.	0.905
dstn	cfl1	ENSSDUP00000002145	ENSSDUP00000024937	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Cofilin 1; Belongs to the actin-binding proteins ADF family.	0.905
il10	LOC111226679	ENSSDUP00000003040	ENSSDUP00000013910	Interleukin 10.	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	0.430
jak1	LOC111232050	ENSSDUP00000017855	ENSSDUP00000003206	Tyrosine-protein kinase.	Interleukin 12 receptor, beta 2a.	0.573
jak1	LOC111236466	ENSSDUP00000017855	ENSSDUP00000032116	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.937
jak1	jak2	ENSSDUP00000017855	ENSSDUP00000022125	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.937
jak2	LOC111232050	ENSSDUP00000022125	ENSSDUP00000003206	Tyrosine-protein kinase.	Interleukin 12 receptor, beta 2a.	0.742