80 items (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bcl2l13	BCL2 like 13. (551 aa)
	tbc1d15	TBC1 domain family, member 15. (667 aa)
	LOC111237674	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (634 aa)
	mfn2	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (711 aa)
	ambra1	Autophagy/beclin-1 regulator 1b. (1380 aa)
	LOC111238800	Tax1 (human T-cell leukemia virus type I) binding protein 1b. (842 aa)
	LOC111221652	Transcription factor EB. (513 aa)
	rhot2	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (618 aa)
	LOC111226981	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (660 aa)
	pgam5	PGAM family member 5, serine/threonine protein phosphatase, mitochondrial. (305 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	eif2ak3	Eukaryotic translation initiation factor 2-alpha kinase 3. (1107 aa)
	LOC111216921	Hypoxia inducible factor 1 subunit alpha, like. (652 aa)
	csnk2a2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (350 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	mfn1	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (758 aa)
	usp8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1088 aa)
	LOC111238835	GABA(A) receptor-associated protein like 2. (126 aa)
	pink1	PTEN induced kinase 1. (575 aa)
	LOC111226417	Mitogen-activated protein kinase. (420 aa)
	LOC111223177	Tax1 (human T-cell leukemia virus type I) binding protein 1a. (955 aa)
	LOC111235128	Tyrosine-protein kinase. (543 aa)
	LOC111237326	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (718 aa)
	fis1	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (154 aa)
	LOC111219534	Mitogen-activated protein kinase. (384 aa)
	jun	BZIP domain-containing protein; Belongs to the bZIP family. (321 aa)
	TOMM7	Translocase of outer mitochondrial membrane 7. (55 aa)
	LOC111226193	Fork-head domain-containing protein. (627 aa)
	LOC111221715	Uncharacterized protein. (207 aa)
	LOC111221678	Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (340 aa)
	calcoco2	SKICH domain-containing protein. (607 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	mras	Muscle RAS oncogene homolog. (218 aa)
	LOC111230109	Zgc:92606. (117 aa)
	LOC111219998	NBR1 autophagy cargo receptor a. (1079 aa)
	LOC111238475	BCL2 interacting protein 3 like b. (223 aa)
	usp30	Ubiquitin carboxyl-terminal hydrolase. (519 aa)
	FUNDC1	FUN14 domain containing 1. (225 aa)
	tbk1	TANK-binding kinase 1. (733 aa)
	LOC111221707	Transcription factor binding to IGHM enhancer 3b. (453 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (463 aa)
	LOC111216707	Activating transcription factor 4a. (459 aa)
	LOC111228782	Ubiquitin A-52 residue ribosomal protein fusion product 1. (132 aa)
	fundc1	Uncharacterized protein. (169 aa)
	LOC111234054	Zgc:86598; Belongs to the protein kinase superfamily. (392 aa)
	LOC111234029	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
	atg9a	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (858 aa)
	e2f1	E2F transcription factor 1. (445 aa)
	optn	Optineurin. (529 aa)
	Epas1	BHLH domain-containing protein. (75 aa)
	bnip3	BCL2 interacting protein 3. (191 aa)
	mapk10	Mitogen-activated protein kinase. (460 aa)
	ubc	Uncharacterized protein. (748 aa)
	LOC111230220	Zgc:55558. (187 aa)
	LOC111233537	Tyrosine-protein kinase. (550 aa)
	ENSSDUP00000024010	Uncharacterized protein. (131 aa)
	rela	V-rel avian reticuloendotheliosis viral oncogene homolog A. (632 aa)
	LOC111236255	PB1 domain-containing protein. (1077 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	rras	RAS related. (201 aa)
	LOC111230364	Activating transcription factor 4b. (455 aa)
	bcl2l1	BCL2 like 1. (232 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	hif1a	Hypoxia inducible factor 1 subunit alpha a. (779 aa)
	foxo3	Forkhead box O3b. (668 aa)
	LOC111221504	Si:dkey-13a21.4. (204 aa)
	LOC111221542	BH4_2 domain-containing protein. (221 aa)
	LOC111223428	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
	LOC111223575	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (333 aa)
	gabarap	GABA(A) receptor-associated protein b. (122 aa)
	MITF	Melanocyte inducing transcription factor. (513 aa)
	LOC111233015	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (377 aa)
	LOC111231609	BCL2 interacting protein 3 like a. (236 aa)
	becn1	Beclin 1, autophagy related. (447 aa)
	ulk1	Unc-51 like autophagy activating kinase 1. (1027 aa)
	tbc1d17	TBC1 domain family, member 17. (628 aa)
	LOC111231860	Unc-51 like autophagy activating kinase 1a. (921 aa)
	LOC111235092	Mitogen-activated protein kinase. (437 aa)
	rras2	RAS related 2. (202 aa)
	LOC111239883	Zgc:73226. (166 aa)

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSDUP00000024010	LOC111219998	ENSSDUP00000024010	ENSSDUP00000015051	Uncharacterized protein.	NBR1 autophagy cargo receptor a.	0.675
ENSSDUP00000024010	LOC111231860	ENSSDUP00000024010	ENSSDUP00000031602	Uncharacterized protein.	Unc-51 like autophagy activating kinase 1a.	0.833
ENSSDUP00000024010	LOC111236255	ENSSDUP00000024010	ENSSDUP00000024349	Uncharacterized protein.	PB1 domain-containing protein.	0.675
ENSSDUP00000024010	LOC111238835	ENSSDUP00000024010	ENSSDUP00000004847	Uncharacterized protein.	GABA(A) receptor-associated protein like 2.	0.464
ENSSDUP00000024010	ambra1	ENSSDUP00000024010	ENSSDUP00000001285	Uncharacterized protein.	Autophagy/beclin-1 regulator 1b.	0.421
ENSSDUP00000024010	atg5	ENSSDUP00000024010	ENSSDUP00000003161	Uncharacterized protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.612
ENSSDUP00000024010	atg9a	ENSSDUP00000024010	ENSSDUP00000019463	Uncharacterized protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.900
ENSSDUP00000024010	becn1	ENSSDUP00000024010	ENSSDUP00000029998	Uncharacterized protein.	Beclin 1, autophagy related.	0.855
ENSSDUP00000024010	gabarap	ENSSDUP00000024010	ENSSDUP00000028085	Uncharacterized protein.	GABA(A) receptor-associated protein b.	0.464
ENSSDUP00000024010	pink1	ENSSDUP00000024010	ENSSDUP00000005112	Uncharacterized protein.	PTEN induced kinase 1.	0.463
ENSSDUP00000024010	ulk1	ENSSDUP00000024010	ENSSDUP00000030142	Uncharacterized protein.	Unc-51 like autophagy activating kinase 1.	0.833
Epas1	LOC111216921	ENSSDUP00000020682	ENSSDUP00000003748	BHLH domain-containing protein.	Hypoxia inducible factor 1 subunit alpha, like.	0.900
Epas1	LOC111219998	ENSSDUP00000020682	ENSSDUP00000015051	BHLH domain-containing protein.	NBR1 autophagy cargo receptor a.	0.499
Epas1	LOC111236255	ENSSDUP00000020682	ENSSDUP00000024349	BHLH domain-containing protein.	PB1 domain-containing protein.	0.499
Epas1	hif1a	ENSSDUP00000020682	ENSSDUP00000026862	BHLH domain-containing protein.	Hypoxia inducible factor 1 subunit alpha a.	0.900
Epas1	rps27a	ENSSDUP00000020682	ENSSDUP00000004225	BHLH domain-containing protein.	Ribosomal protein S27a.	0.501
FUNDC1	LOC111219998	ENSSDUP00000016752	ENSSDUP00000015051	FUN14 domain containing 1.	NBR1 autophagy cargo receptor a.	0.566
FUNDC1	LOC111221678	ENSSDUP00000016752	ENSSDUP00000011379	FUN14 domain containing 1.	Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily.	0.944
FUNDC1	LOC111223428	ENSSDUP00000016752	ENSSDUP00000027405	FUN14 domain containing 1.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.954
FUNDC1	LOC111223575	ENSSDUP00000016752	ENSSDUP00000027575	FUN14 domain containing 1.	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily.	0.944