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cbiA cbiA cbiB cbiB ABX20774.1 ABX20774.1 cbiD cbiD ABX20776.1 ABX20776.1 ABX20777.1 ABX20777.1 ABX20778.1 ABX20778.1 ABX20779.1 ABX20779.1 ABX20780.1 ABX20780.1 ABX20781.1 ABX20781.1 ABX20782.1 ABX20782.1 ABX20783.1 ABX20783.1 cbiM cbiM cbiN cbiN ABX20786.1 ABX20786.1 cbiO cbiO cobQ cobQ ABX20789.1 ABX20789.1 cobS cobS cobT cobT ABX21144.1 ABX21144.1 ABX22078.1 ABX22078.1 ABX22152.1 ABX22152.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cbiAHypothetical protein; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (459 aa)
cbiBHypothetical protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. However, the true cosubstrate could be (R)-1-amino-2-propanol O-2-phosphate, leading to cobinamide phosphate. (319 aa)
ABX20774.1Hypothetical protein; KEGG: stm:STM2033 2.4e-107 cbiC; precorrin-8X methylmutase K03400; COG: COG2082 Precorrin isomerase; Psort location: Cytoplasmic, score:8.96. (210 aa)
cbiDHypothetical protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (379 aa)
ABX20776.1Hypothetical protein; KEGG: spt:SPA0840 3.2e-103 cbiE; precorrin-6Y C5,15-methyltransferase K03399; COG: COG2241 Precorrin-6B methylase 1; Psort location: Cytoplasmic, score:8.96. (201 aa)
ABX20777.1Hypothetical protein; KEGG: stm:STM2030 2.2e-97 cbiT; precorrin-8W decarboxylase K02191; COG: COG2242 Precorrin-6B methylase 2. (189 aa)
ABX20778.1Hypothetical protein; KEGG: stm:STM2029 8.7e-133 cbiF; precorrin-4 C11-methyltransferase K03396; COG: COG2875 Precorrin-4 methylase; Psort location: Cytoplasmic, score:8.96. (257 aa)
ABX20779.1Hypothetical protein; KEGG: dde:Dde_3181 1.5e-41 precorrin-3B C17-methyltransferase K02189:K03395:K00594; COG: COG2073 Cobalamin biosynthesis protein CbiG; Psort location: Cytoplasmic, score:8.96. (351 aa)
ABX20780.1Hypothetical protein; KEGG: sec:SC2035 1.0e-122 cbiH; synthesis of vitamin B12 adenosyl cobalamide precursor K03395; COG: COG1010 Precorrin-3B methylase. (241 aa)
ABX20781.1Hypothetical protein; KEGG: stm:STM2026 4.5e-136 cbiJ; precorrin-6X reductase K03397; COG: COG2099 Precorrin-6x reductase. (263 aa)
ABX20782.1Hypothetical protein; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. (264 aa)
ABX20783.1Hypothetical protein; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. (234 aa)
cbiMHypothetical protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. (245 aa)
cbiNHypothetical protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (93 aa)
ABX20786.1Hypothetical protein; COG: COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; Psort location: CytoplasmicMembrane, score:10.00. (225 aa)
cbiOHypothetical protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. (271 aa)
cobQHypothetical protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (506 aa)
ABX20789.1Hypothetical protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (181 aa)
cobSHypothetical protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (247 aa)
cobTHypothetical protein; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). Belongs to the CobT family. (354 aa)
ABX21144.1Hypothetical protein; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (196 aa)
ABX22078.1Hypothetical protein; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (200 aa)
ABX22152.1Hypothetical protein; KEGG: sec:SC0673 7.0e-108 cobC; alpha ribazole-5'-P phosphatase in cobalamin synthesis K02226; COG: COG0406 Fructose-2,6-bisphosphatase; Psort location: Cytoplasmic, score:8.96; Belongs to the phosphoglycerate mutase family. (206 aa)
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
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