STRINGSTRING
yggX yggX ABX24256.1 ABX24256.1 ABX24254.1 ABX24254.1 ygiQ ygiQ tsaD tsaD ABX23973.1 ABX23973.1 feoC feoC nfuA nfuA ABX23614.1 ABX23614.1 cyaY cyaY fdhE fdhE ABX23324.1 ABX23324.1 nrfA nrfA ABX23100.1 ABX23100.1 ABX23044.1 ABX23044.1 ABX22768.1 ABX22768.1 erpA erpA ABX22213.1 ABX22213.1 hutI hutI bioB bioB dps dps rlmC rlmC ABX21782.1 ABX21782.1 ABX21368.1 ABX21368.1 ABX21366.1 ABX21366.1 ABX21364.1 ABX21364.1 ABX21234.1 ABX21234.1 lapB lapB ABX21055.1 ABX21055.1 ABX21052.1 ABX21052.1 ABX20917.1 ABX20917.1 ABX20912.1 ABX20912.1 ABX20909.1 ABX20909.1 napA napA nuoI nuoI iscA iscA ABX20273.1 ABX20273.1 iscR iscR ABX20150.1 ABX20150.1 glaH glaH luxS luxS norV norV ABX20069.1 ABX20069.1 rlmD rlmD nuoB nuoB ispG ispG ABX20278.1 ABX20278.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yggXHypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. (91 aa)
ABX24256.1Hypothetical protein; COG: COG0298 Hydrogenase maturation factor; Psort location: Cytoplasmic, score:8.96. (82 aa)
ABX24254.1Hypothetical protein; COG: NOG08099 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96. (162 aa)
ygiQKEGG: eci:UTI89_C3435 0. hypothetical protein; COG: COG1032 Fe-S oxidoreductase. (723 aa)
tsaDHypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (337 aa)
ABX23973.1Hypothetical protein; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (158 aa)
feoCHypothetical protein; May function as a transcriptional regulator that controls feoABC expression. (81 aa)
nfuAHypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (191 aa)
ABX23614.1Hypothetical protein; KEGG: eci:UTI89_C2480 6.1e-45 napC; cytochrome c protein, subunit of nitrate reductase, periplasmic K02569; COG: COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit; Belongs to the TorC/TorY family. (394 aa)
cyaYHypothetical protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (106 aa)
fdhEHypothetical protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (309 aa)
ABX23324.1Hypothetical protein; KEGG: mac:MA0154 1.0e-11 bioB; biotin synthase K01012; COG: COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (377 aa)
nrfAHypothetical protein; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family. (478 aa)
ABX23100.1Hypothetical protein; COG: COG1959 Predicted transcriptional regulator. (125 aa)
ABX23044.1Hypothetical protein; KEGG: eco:b4236 3.1e-41 cybC; cytochrome b562, truncated (pseudogene); COG: COG3783 Soluble cytochrome b562; Psort location: Periplasmic, score:9.76. (128 aa)
ABX22768.1Hypothetical protein; Could be a 3Fe-4S cluster-containing protein. (95 aa)
erpAHypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. (114 aa)
ABX22213.1Hypothetical protein; KEGG: btk:BT9727_2470 2.4e-12 probable esterase K07214; COG: COG2382 Enterochelin esterase and related enzymes; Psort location: Cytoplasmic, score:9.97. (405 aa)
hutIHypothetical protein; KEGG: sec:SC0785 2.1e-202 hutI; imidazolonepropionase K01468; COG: COG1228 Imidazolonepropionase and related amidohydrolases; Psort location: Cytoplasmic, score:8.96; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (407 aa)
bioBHypothetical protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (346 aa)
dpsHypothetical protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. (167 aa)
rlmCHypothetical protein; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily. (375 aa)
ABX21782.1Hypothetical protein; KEGG: stm:STM1103 1.3e-154 hpaD; 4-hydroxyphenylacetate catabolism K00455; COG: COG3384 Uncharacterized conserved protein; Psort location: Cytoplasmic, score:8.96. (283 aa)
ABX21368.1Hypothetical protein; KEGG: eci:UTI89_C1042 1.7e-65 hyaC; probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit K03620; COG: COG1969 Ni,Fe-hydrogenase I cytochrome b subunit; Psort location: CytoplasmicMembrane, score:10.00. (242 aa)
ABX21366.1Hypothetical protein; COG: NOG17080 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96. (99 aa)
ABX21364.1Hypothetical protein; KEGG: eci:UTI89_C1045 6.2e-36 hyaF; hydrogenase-1 operon protein HyaF K03618; COG: COG1773 Rubredoxin; Psort location: Cytoplasmic, score:8.96. (353 aa)
ABX21234.1Hypothetical protein; KEGG: spt:SPA1236 0. nifJ; probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (1174 aa)
lapBHypothetical protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (389 aa)
ABX21055.1Hypothetical protein; KEGG: eci:UTI89_C1042 5.3e-110 hyaC; probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit K03620; COG: COG1969 Ni,Fe-hydrogenase I cytochrome b subunit; Psort location: CytoplasmicMembrane, score:10.00. (243 aa)
ABX21052.1Hypothetical protein; KEGG: eci:UTI89_C1045 6.6e-112 hyaF; hydrogenase-1 operon protein HyaF K03618; COG: NOG06279 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96. (282 aa)
ABX20917.1Hypothetical protein; Iron-storage protein. (167 aa)
ABX20912.1Hypothetical protein; Iron-storage protein. (165 aa)
ABX20909.1Hypothetical protein; COG: COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA; Psort location: Cytoplasmic, score:8.96; Belongs to the UPF0149 family. (221 aa)
napAHypothetical protein; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (828 aa)
nuoIHypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (190 aa)
iscAHypothetical protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. (107 aa)
ABX20273.1Hypothetical protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (128 aa)
iscRHypothetical protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. (164 aa)
ABX20150.1Hypothetical protein; KEGG: btk:BT9727_2470 2.0e-07 probable esterase K07214; COG: COG2382 Enterochelin esterase and related enzymes; Psort location: Cytoplasmic, score:9.26. (414 aa)
glaHHypothetical protein; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (328 aa)
luxSHypothetical protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (171 aa)
norVHypothetical protein; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family. (479 aa)
ABX20069.1Hypothetical protein; COG: COG0298 Hydrogenase maturation factor. (90 aa)
rlmDHypothetical protein; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (431 aa)
nuoBHypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (220 aa)
ispGHypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (372 aa)
ABX20278.1COG: COG2975 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96. (66 aa)
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
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