STRINGSTRING
ABX20128.1 ABX20128.1 ABX20129.1 ABX20129.1 lhgD lhgD glaH glaH ABX20256.1 ABX20256.1 fadJ fadJ ABX20465.1 ABX20465.1 patD patD ABX22083.1 ABX22083.1 ABX22617.1 ABX22617.1 ABX22686.1 ABX22686.1 ABX22896.1 ABX22896.1 fadB fadB patA patA ABX24405.1 ABX24405.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABX20128.1Hypothetical protein; KEGG: stm:STM2792 3.2e-222 gabT; 4-aminobutyrate aminotransferase K00823:K07250; COG: COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Psort location: Cytoplasmic, score:8.96; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
ABX20129.1Hypothetical protein; KEGG: stm:STM2791 9.0e-250 gabD; succinate-semialdehyde dehydrogenase I K00135; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.97. (482 aa)
lhgDHypothetical protein; Catalyzes the dehydrogenation of L-2-hydroxyglutarate (L2HG) to alpha-ketoglutarate and couples to the respiratory chain by feeding electrons from the reaction into the membrane quinone pool. Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. Reaction=(S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol; Xref=Rhea:RHEA:58664, ChEBI:CHEBI:16782, ChEBI:CHEBI:16810, ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:58665; Belongs to the L2HGDH family. (422 aa)
glaHHypothetical protein; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (328 aa)
ABX20256.1Hypothetical protein; KEGG: stt:t0297 0. cadA; lysine decarboxylase K01582; COG: COG1982 Arginine/lysine/ornithine decarboxylases. (714 aa)
fadJHypothetical protein; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (714 aa)
ABX20465.1Hypothetical protein; KEGG: stt:t0504 7.3e-255 putative amino acid decarboxylase K01586; COG: COG0019 Diaminopimelate decarboxylase; Psort location: Cytoplasmic, score:8.96. (465 aa)
patDHypothetical protein; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4- aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (474 aa)
ABX22083.1Hypothetical protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (406 aa)
ABX22617.1Hypothetical protein; KEGG: sec:SC0234 0. ldcC; lysine decarboxylase 2, constitutive K01582; COG: COG1982 Arginine/lysine/ornithine decarboxylases; Psort location: Cytoplasmic, score:8.96. (713 aa)
ABX22686.1Hypothetical protein; KEGG: stt:t0160 2.0e-252 lpdA; dihydrolipoamide dehydrogenase K00382; COG: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; Psort location: Cytoplasmic, score:9.97. (475 aa)
ABX22896.1Hypothetical protein; KEGG: stm:STM4519 3.0e-233 putative NAD-dependent aldehyde dehydrogenase K00135; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.97. (456 aa)
fadBHypothetical protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (755 aa)
patAHypothetical protein; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (429 aa)
ABX24405.1Hypothetical protein; KEGG: stt:t2929 9.3e-200 yqeF; probable acetyl-CoA acetyltransferase K00626; COG: COG0183 Acetyl-CoA acetyltransferase; Psort location: Cytoplasmic, score:9.97; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
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