STRINGSTRING
lpxP lpxP arnT arnT lpxT lpxT lpxM lpxM kdsA kdsA ABX21534.1 ABX21534.1 ABX21540.1 ABX21540.1 lpxL lpxL kdsB kdsB lpxK lpxK pagP pagP lpxH lpxH gmhA gmhA ABX22602.1 ABX22602.1 lpxB lpxB lpxA lpxA lpxD lpxD lpxC lpxC ABX23196.1 ABX23196.1 ABX23361.1 ABX23361.1 ABX23710.1 ABX23710.1 ABX23712.1 ABX23712.1 ABX23713.1 ABX23713.1 ABX23714.1 ABX23714.1 ABX23716.1 ABX23716.1 ABX23717.1 ABX23717.1 ABX23718.1 ABX23718.1 ABX23719.1 ABX23719.1 ABX23720.1 ABX23720.1 ABX23722.1 ABX23722.1 ABX23723.1 ABX23723.1 ABX23724.1 ABX23724.1 hldD hldD ABX23793.1 ABX23793.1 ABX24091.1 ABX24091.1 ABX24092.1 ABX24092.1 hldE hldE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lpxPHypothetical protein; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily. (306 aa)
arnTHypothetical protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. (548 aa)
lpxTHypothetical protein; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. (239 aa)
lpxMHypothetical protein; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (323 aa)
kdsAHypothetical protein; KEGG: stm:STM1772 3.8e-148 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) K01627; COG: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Psort location: Cytoplasmic, score:8.96; Belongs to the KdsA family. (284 aa)
ABX21534.1Hypothetical protein; KEGG: spt:SPA3566 1.7e-113 waaK; lipopolysaccharide 1,2-N-acetylglucosaminetransferase K03280; COG: COG0438 Glycosyltransferase. (380 aa)
ABX21540.1COG: COG3528 Uncharacterized protein conserved in bacteria. (300 aa)
lpxLHypothetical protein; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (306 aa)
kdsBHypothetical protein; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (248 aa)
lpxKHypothetical protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (325 aa)
pagPHypothetical protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. (190 aa)
lpxHHypothetical protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (240 aa)
gmhAHypothetical protein; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (198 aa)
ABX22602.1Hypothetical protein; KEGG: sty:STY0275 2.8e-95 yaeD; D-glycero-D-manno-heptose 1 phosphatase K03273; COG: COG0241 Histidinol phosphatase and related phosphatases; Psort location: Cytoplasmic, score:8.96. (188 aa)
lpxBHypothetical protein; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (382 aa)
lpxAHypothetical protein; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa)
lpxDHypothetical protein; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (341 aa)
lpxCHypothetical protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (305 aa)
ABX23196.1Hypothetical protein; KEGG: pha:PSHAa2772 4.8e-93 eptA; lipid A phosphoethanolamine transferase, associated with polymyxin resistance K03760; COG: COG2194 Predicted membrane-associated, metal-dependent hydrolase; Psort location: CytoplasmicMembrane, score:9.46. (547 aa)
ABX23361.1Hypothetical protein; KEGG: pha:PSHAa2772 6.8e-21 eptA; lipid A phosphoethanolamine transferase, associated with polymyxin resistance K03760; COG: COG2194 Predicted membrane-associated, metal-dependent hydrolase; Psort location: CytoplasmicMembrane, score:10.00. (577 aa)
ABX23710.1Hypothetical protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (425 aa)
ABX23712.1Hypothetical protein; KEGG: sty:STY4071 8.9e-179 rfaQ, waaQ; lipopolysaccharide heptosyltransferase III K02849; COG: COG0859 ADP-heptose:LPS heptosyltransferase. (344 aa)
ABX23713.1Hypothetical protein; KEGG: stm:STM3722 2.5e-197 rfaG, waaG; UDP-glucose:(heptosyl)lipopolysaccharide alpha-1,3-glucosyltransferase K02844; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score:8.96. (374 aa)
ABX23714.1Hypothetical protein; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family. (265 aa)
ABX23716.1Hypothetical protein; KEGG: sec:SC3642 3.5e-184 rfaB; UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase K02840; COG: COG0438 Glycosyltransferase. (363 aa)
ABX23717.1Hypothetical protein; KEGG: stt:t3801 1.1e-171 waaI; lipopolysaccharide 1,3-galactosyltransferase K03278; COG: COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases. (337 aa)
ABX23718.1Hypothetical protein; KEGG: stm:STM3717 1.8e-171 rfaJ, waaJ; UDP-D-glucose:(galactosyl)lipopolysaccharide alpha-1,2-glucosyltransferase K03279; COG: COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases. (336 aa)
ABX23719.1Hypothetical protein; KEGG: stt:t3803 1.6e-115 waaY; lipopolysaccharide core biosynthesis protein K02850; COG: NOG10262 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96. (232 aa)
ABX23720.1Hypothetical protein; COG: NOG06879 non supervised orthologous group. (269 aa)
ABX23722.1Hypothetical protein; KEGG: sec:SC3636 2.3e-203 waaL; hypothetical protein K02847; COG: COG3307 Lipid A core - O-antigen ligase and related enzymes; Psort location: CytoplasmicMembrane, score:10.00. (404 aa)
ABX23723.1Hypothetical protein; KEGG: stt:t3807 3.1e-169 waaC; lipopolysaccharide heptosyltransferase-1 K02841; COG: COG0859 ADP-heptose:LPS heptosyltransferase. (317 aa)
ABX23724.1Hypothetical protein; KEGG: spt:SPA3563 5.7e-184 waaF; ADP-heptose-LPS heptosyltransferase II K02843; COG: COG0859 ADP-heptose:LPS heptosyltransferase. (348 aa)
hldDHypothetical protein; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (310 aa)
ABX23793.1Hypothetical protein; KEGG: pha:PSHAa2772 3.0e-28 eptA; lipid A phosphoethanolamine transferase, associated with polymyxin resistance K03760; COG: COG2194 Predicted membrane-associated, metal-dependent hydrolase; Psort location: CytoplasmicMembrane, score:10.00. (563 aa)
ABX24091.1Hypothetical protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. (188 aa)
ABX24092.1Hypothetical protein; KEGG: stm:STM3315 2.4e-169 yrbH; putative sugar phosphate isomerase K06041; COG: COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Psort location: Cytoplasmic, score:8.96. (328 aa)
hldEHypothetical protein; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. (477 aa)
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
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