STRINGSTRING
ABX20347.1 ABX20347.1 ABX20354.1 ABX20354.1 ABX20357.1 ABX20357.1 accD accD ABX20488.1 ABX20488.1 ackA ackA dld dld ABX20966.1 ABX20966.1 ABX21106.1 ABX21106.1 ABX21234.1 ABX21234.1 ABX21237.1 ABX21237.1 maeA maeA fumC fumC ABX21406.1 ABX21406.1 ABX21442.1 ABX21442.1 ABX21488.1 ABX21488.1 ABX21496.1 ABX21496.1 ABX21511.1 ABX21511.1 ghrA ghrA yccX yccX ABX21844.1 ABX21844.1 ABX21870.1 ABX21870.1 ABX21906.1 ABX21906.1 ABX21957.1 ABX21957.1 ABX22077.1 ABX22077.1 gloB gloB accA accA ABX22686.1 ABX22686.1 ABX22688.1 ABX22688.1 ABX22689.1 ABX22689.1 leuA leuA ABX23123.1 ABX23123.1 ABX23124.1 ABX23124.1 frdC frdC frdD frdD ABX23179.1 ABX23179.1 acs acs ABX23302.1 ABX23302.1 ppc ppc lldD lldD ABX23763.1 ABX23763.1 ABX23787.1 ABX23787.1 pckA pckA ABX24036.1 ABX24036.1 ABX24037.1 ABX24037.1 mdh mdh ABX24156.1 ABX24156.1 ABX24340.1 ABX24340.1 ABX24405.1 ABX24405.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABX20347.1Hypothetical protein; KEGG: sty:STY2709 0. maeB; NADP-dependent malate dehydrogenase (decarboxylating) K00029; COG: COG0280 Phosphotransacetylase. (759 aa)
ABX20354.1Hypothetical protein; KEGG: eci:UTI89_C2782 3.1e-153 eutD, ypfA, eutI; ethanolamine utilization protein EutD acetyl/butyryl phosphate transferase K04020; COG: COG0280 Phosphotransacetylase. (338 aa)
ABX20357.1Hypothetical protein; KEGG: rru:Rru_A0914 5.4e-101 aldehyde dehydrogenase K04021; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:8.96. (467 aa)
accDHypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (330 aa)
ABX20488.1Hypothetical protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (709 aa)
ackAHypothetical protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
dldHypothetical protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (600 aa)
ABX20966.1Hypothetical protein; KEGG: spt:SPA0981 1.9e-247 pykA; pyruvate kinase A K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score:8.96. (480 aa)
ABX21106.1Hypothetical protein; KEGG: stm:STM1749 0. adhE; alcohol dehydrogenase / acetaldehyde dehydrogenase K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.26; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (892 aa)
ABX21234.1Hypothetical protein; KEGG: spt:SPA1236 0. nifJ; probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (1174 aa)
ABX21237.1Hypothetical protein; KEGG: spt:SPA1239 3.0e-171 ldhA; D-lactate dehydrogenase K03778; COG: COG1052 Lactate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score:9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
maeAHypothetical protein; KEGG: spt:SPA1302 0. sfcA; NAD-linked malic enzyme; malate oxidoreductase K00027; COG: COG0281 Malic enzyme; Belongs to the malic enzymes family. (565 aa)
fumCHypothetical protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (481 aa)
ABX21406.1Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa)
ABX21442.1Hypothetical protein; KEGG: sec:SC1454 8.2e-66 gloA; glyoxalase I, nickel isomerase K01759; COG: COG0346 Lactoylglutathione lyase and related lyases. (129 aa)
ABX21488.1Hypothetical protein; COG: NOG13889 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96. (104 aa)
ABX21496.1Hypothetical protein; KEGG: stm:STM1378 6.2e-242 pykF; pyruvate kinase I (formerly F), fructose stimulated K00873; COG: COG0469 Pyruvate kinase. (470 aa)
ABX21511.1Hypothetical protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
ghrAHypothetical protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. (312 aa)
yccXHypothetical protein; KEGG: stm:STM1083 1.6e-44 yccX; putative phosphohydrolase K01512; COG: COG1254 Acylphosphatases; Psort location: Cytoplasmic, score:8.96. (93 aa)
ABX21844.1Hypothetical protein; KEGG: eci:UTI89_C0999 9.6e-111 ycbL; hypothetical protein K01069; COG: COG0491 Zn-dependent hydrolases, including glyoxylases. (215 aa)
ABX21870.1Hypothetical protein; KEGG: stm:STM0973 0. pflB; pyruvate formate lyase I K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score:9.97. (760 aa)
ABX21906.1Hypothetical protein; KEGG: stm:STM0935 1.4e-301 poxB; pyruvate dehydrogenase K00156; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.96; Belongs to the TPP enzyme family. (572 aa)
ABX21957.1Hypothetical protein; KEGG: sec:SC0838 0. pflF; putative pyruvate formate lyase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score:9.97. (810 aa)
ABX22077.1Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (550 aa)
gloBHypothetical protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (251 aa)
accAHypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa)
ABX22686.1Hypothetical protein; KEGG: stt:t0160 2.0e-252 lpdA; dihydrolipoamide dehydrogenase K00382; COG: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; Psort location: Cytoplasmic, score:9.97. (475 aa)
ABX22688.1Hypothetical protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (626 aa)
ABX22689.1Hypothetical protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa)
leuAHypothetical protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (523 aa)
ABX23123.1Hypothetical protein; KEGG: sec:SC4222 0. frdA; fumarate reductase, anaerobic, flavoprotein subunit K00244; COG: COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Psort location: Periplasmic, score:9.44. (624 aa)
ABX23124.1Hypothetical protein; KEGG: stm:STM4342 4.7e-134 frdB; fumarate reductase, anaerobic, Fe-S protein subunit K00245; COG: COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Psort location: Cytoplasmic, score:8.96. (244 aa)
frdCHypothetical protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (120 aa)
frdDHypothetical protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa)
ABX23179.1Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa)
acsHypothetical protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (652 aa)
ABX23302.1Hypothetical protein; KEGG: stm:STM4183 4.6e-285 aceB; malate synthase A K01638; COG: COG2225 Malate synthase; Psort location: Cytoplasmic, score:9.97. (533 aa)
ppcHypothetical protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (883 aa)
lldDHypothetical protein; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. (396 aa)
ABX23763.1Hypothetical protein; KEGG: spt:SPA3531 1.2e-277 aldB; aldehyde dehydrogenase B K00138; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.26. (522 aa)
ABX23787.1Hypothetical protein; KEGG: sec:SC3578 5.5e-76 yiaE; 2-keto-D-gluconate reductase K00090; COG: COG1052 Lactate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score:9.97. (164 aa)
pckAHypothetical protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (539 aa)
ABX24036.1Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
ABX24037.1Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (156 aa)
mdhHypothetical protein; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa)
ABX24156.1Hypothetical protein; KEGG: stm:STM3241 0. tdcE; pyruvate formate-lyase 4/2-ketobutyrate formate-lyase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score:9.97. (764 aa)
ABX24340.1Hypothetical protein; COG: COG3722 Transcriptional regulator. (169 aa)
ABX24405.1Hypothetical protein; KEGG: stt:t2929 9.3e-200 yqeF; probable acetyl-CoA acetyltransferase K00626; COG: COG0183 Acetyl-CoA acetyltransferase; Psort location: Cytoplasmic, score:9.97; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
Server load: low (10%) [HD]