STRINGSTRING
rpl13e rpl13e rps15 rps15 rps24e rps24e infB infB rps17e rps17e rps13 rps13 rps4 rps4 rpl18e rpl18e rps9 rps9 rps2 rps2 rps28e rps28e rpl24e rpl24e rpl15e rpl15e rpl37ae rpl37ae Hbut_0579 Hbut_0579 Hbut_0776 Hbut_0776 rpl35ae rpl35ae Hbut_1104 Hbut_1104 rpl2 rpl2 rps19 rps19 rpl23 rpl23 rpl22 rpl22 rpl29 rpl29 rps17 rps17 rpl14 rpl14 rpl5 rpl5 rps14 rps14 rps8 rps8 rpl6 rpl6 Hbut_1317 Hbut_1317 rpl19e rpl19e rpl18 rpl18 rps5 rps5 rpl30 rpl30 rpl15 rpl15 rpl34e rpl34e rpl14e rpl14e Hbut_1480 Hbut_1480 rpl30e rpl30e rps12 rps12 rps7 rps7 rps10 rps10 rps19e rps19e rpl31e rpl31e eif6 eif6 rpl18a rpl18a rpl11 rpl11 rpl1 rpl1 rpl44e rpl44e rpl10e rpl10e rpl21e rpl21e eIF5A eIF5A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpl13e50S ribosomal protein L13e; Belongs to the eukaryotic ribosomal protein eL13 family. (88 aa)
rps1530S ribosomal protein S13e. (161 aa)
rps24e30S ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (122 aa)
infBTranslation initiation factor 2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (612 aa)
rps17e30S ribosomal protein S17e; The protein has a longer C terminal than otherwise seen in archaea; Belongs to the eukaryotic ribosomal protein eS17 family. (103 aa)
rps1330S ribosomal protein S13p; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (151 aa)
rps430S ribosomal protein S4p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (176 aa)
rpl18e50S ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family. (123 aa)
rps930S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (158 aa)
rps230S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (216 aa)
rps28e30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (81 aa)
rpl24e50S ribosomal protein L24e; Binds to the 23S rRNA. (61 aa)
rpl15e50S ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family. (226 aa)
rpl37ae50S ribosomal protein L37Ae; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily. (88 aa)
Hbut_057950S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (57 aa)
Hbut_077630S ribosomal protein S26. (96 aa)
rpl35ae50S ribosomal protein L35Ae; Belongs to the eukaryotic ribosomal protein eL33 family. (106 aa)
Hbut_110430S ribosomal protein S25e. (76 aa)
rpl250S ribosomal protein L2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (238 aa)
rps1930S ribosomal protein S19p; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (155 aa)
rpl2350S ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (88 aa)
rpl2250S ribosomal protein L22; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (156 aa)
rpl2950S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (77 aa)
rps1730S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (116 aa)
rpl1450S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (138 aa)
rpl550S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (196 aa)
rps1430S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (57 aa)
rps830S ribosomal protein S8p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (133 aa)
rpl650S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (186 aa)
Hbut_131750S ribosomal protein L32E. (122 aa)
rpl19e50S ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (153 aa)
rpl1850S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (211 aa)
rps550S ribosomal protein S5p; With S4 and S12 plays an important role in translational accuracy. (213 aa)
rpl3050S ribosomal protein L30P. (184 aa)
rpl1550S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (151 aa)
rpl34e50S ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family. (106 aa)
rpl14e50S ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family. (98 aa)
Hbut_1480Ribosomal protein 10e. (151 aa)
rpl30e50S ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family. (112 aa)
rps1230S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa)
rps730S ribosomal protein S7p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (202 aa)
rps1030S ribosomal protein S10p; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rps19e30S ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (153 aa)
rpl31e50S ribosomal protein L31e; Belongs to the eukaryotic ribosomal protein eL31 family. (100 aa)
eif6Translation initiation factor 6 (eIF-6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (225 aa)
rpl18a50S ribosomal protein LX. (87 aa)
rpl1150S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (168 aa)
rpl150S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (217 aa)
rpl44e50S ribosomal protein L44e; Binds to the 23S rRNA. (95 aa)
rpl10e50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family. (180 aa)
rpl21e50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (107 aa)
eIF5ATranslation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (136 aa)
Your Current Organism:
Hyperthermus butylicus
NCBI taxonomy Id: 415426
Other names: H. butylicus DSM 5456, Hyperthermus butylicus DSM 5456, Hyperthermus butylicus str. DSM 5456, Hyperthermus butylicus strain DSM 5456
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.