STRINGSTRING
glyA glyA Hbut_1236 Hbut_1236 Hbut_1229 Hbut_1229 Hbut_1214 Hbut_1214 Hbut_1206 Hbut_1206 Hbut_1205 Hbut_1205 Hbut_1199 Hbut_1199 rad50 rad50 mre11 mre11 Hbut_1177 Hbut_1177 Hbut_1174 Hbut_1174 Hbut_1170 Hbut_1170 tmcA-3 tmcA-3 Hbut_1139 Hbut_1139 tfe tfe Hbut_1123 Hbut_1123 Hbut_1119 Hbut_1119 taw1 taw1 Hbut_1104 Hbut_1104 priL priL Hbut_1092 Hbut_1092 Hbut_1068 Hbut_1068 Hbut_1067 Hbut_1067 Hbut_1064 Hbut_1064 Hbut_1039 Hbut_1039 pdxS pdxS Hbut_0599 Hbut_0599 tmcA tmcA Hbut_0648 Hbut_0648 rnz rnz Hbut_0681 Hbut_0681 Hbut_0689 Hbut_0689 Hbut_0697 Hbut_0697 Hbut_0720 Hbut_0720 Hbut_0738 Hbut_0738 Hbut_0739 Hbut_0739 Hbut_0756 Hbut_0756 Hbut_0775 Hbut_0775 Hbut_0776 Hbut_0776 atpB atpB Hbut_0786 Hbut_0786 Hbut_0802 Hbut_0802 Hbut_0806 Hbut_0806 Hbut_0827 Hbut_0827 Hbut_0839 Hbut_0839 Hbut_0845 Hbut_0845 rpl35ae rpl35ae dnaG dnaG Hbut_0896 Hbut_0896 Hbut_0897 Hbut_0897 rfcL rfcL Hbut_0909 Hbut_0909 Hbut_0915 Hbut_0915 albA albA tbp tbp tmcA-2 tmcA-2 Hbut_0955 Hbut_0955 top6A top6A radA radA Hbut_0970 Hbut_0970 albA-2 albA-2 Hbut_0981 Hbut_0981 Hbut_1010 Hbut_1010 Hbut_1022 Hbut_1022 Hbut_1025 Hbut_1025 rpl21e rpl21e Hbut_1657 Hbut_1657 rpl10e rpl10e priS priS rpl44e rpl44e Hbut_1638 Hbut_1638 Hbut_1636 Hbut_1636 Hbut_1627 Hbut_1627 Hbut_1624 Hbut_1624 Hbut_1618 Hbut_1618 rpl1 rpl1 rpl11 rpl11 ftsY ftsY rpl18a rpl18a rpl31e rpl31e rps19e rps19e nep1-2 nep1-2 Hbut_1589 Hbut_1589 Hbut_1584 Hbut_1584 rps10 rps10 rps7 rps7 rps12 rps12 rpl30e rpl30e Hbut_1569 Hbut_1569 Hbut_1562 Hbut_1562 Hbut_1558 Hbut_1558 Hbut_1556 Hbut_1556 Hbut_1555 Hbut_1555 Hbut_1531 Hbut_1531 Hbut_1530 Hbut_1530 Hbut_1529 Hbut_1529 Hbut_1527 Hbut_1527 panB panB Hbut_1515 Hbut_1515 sat sat Hbut_1493 Hbut_1493 Hbut_1488 Hbut_1488 Hbut_1480 Hbut_1480 Hbut_1472 Hbut_1472 Hbut_1468 Hbut_1468 cobB cobB pckG pckG Hbut_1440 Hbut_1440 Hbut_1375 Hbut_1375 Hbut_1374 Hbut_1374 kptA kptA fen fen Hbut_1355 Hbut_1355 Hbut_1354 Hbut_1354 rpl34e rpl34e rps5 rps5 rpl18 rpl18 rpl19e rpl19e Hbut_1317 Hbut_1317 rpl6 rpl6 rps8 rps8 rps14 rps14 rpl5 rpl5 rps4e rps4e rpl24 rpl24 rpl14 rpl14 rps17 rps17 rpl29 rpl29 rps3 rps3 rpl22 rpl22 rpl23 rpl23 Hbut_1302 Hbut_1302 Hbut_1301 Hbut_1301 Hbut_1254 Hbut_1254 Hbut_1297 Hbut_1297 rps19 rps19 Hbut_1281 Hbut_1281 Hbut_1274 Hbut_1274 Hbut_1265 Hbut_1265 Hbut_1259 Hbut_1259 Hbut_1257 Hbut_1257 truB truB rpl14e rpl14e Hbut_0004 Hbut_0004 Hbut_0016 Hbut_0016 Hbut_0025 Hbut_0025 Hbut_0030 Hbut_0030 flpA flpA Hbut_0042 Hbut_0042 ubiX ubiX endA endA Hbut_0064 Hbut_0064 Hbut_0081 Hbut_0081 Hbut_0087 Hbut_0087 Hbut_0088 Hbut_0088 rpl13e rpl13e Hbut_0108 Hbut_0108 Hbut_0112 Hbut_0112 Hbut_0131 Hbut_0131 Hbut_0154 Hbut_0154 Hbut_0157 Hbut_0157 Hbut_0192 Hbut_0192 Hbut_0196 Hbut_0196 hemA hemA Hbut_0223 Hbut_0223 Hbut_0230 Hbut_0230 Hbut_0236 Hbut_0236 Hbut_0262 Hbut_0262 Hbut_0265 Hbut_0265 Hbut_0266 Hbut_0266 Hbut_0291 Hbut_0291 Hbut_0317 Hbut_0317 nep1 nep1 Hbut_0367 Hbut_0367 Hbut_0395 Hbut_0395 Hbut_0399 Hbut_0399 rpl12 rpl12 Hbut_0420 Hbut_0420 lig lig rps3ae rps3ae rps15 rps15 rps24e rps24e rps6e rps6e rps8e rps8e Hbut_0457 Hbut_0457 tgtA tgtA Hbut_0474 Hbut_0474 Hbut_0480 Hbut_0480 rps17e rps17e rbcL rbcL Hbut_0519 Hbut_0519 Hbut_0521 Hbut_0521 Hbut_0522 Hbut_0522 rps13 rps13 rps4 rps4 rpl18e rpl18e rps9 rps9 rps2 rps2 fni fni rps28e rps28e rpl24e rpl24e rpl15e rpl15e Hbut_0569 Hbut_0569 rpl37ae rpl37ae Hbut_0574 Hbut_0574 Hbut_0577 Hbut_0577 Hbut_0579 Hbut_0579 Hbut_0586 Hbut_0586 Hbut_0588 Hbut_0588 Hbut_0590 Hbut_0590 Hbut_0595 Hbut_0595 Hbut_0596 Hbut_0596
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (438 aa)
Hbut_1236Predicted nonsense mediated mRNA decay. (247 aa)
Hbut_1229Conserved crenarchaeal protein. (345 aa)
Hbut_1214Predicted metal-dependent hydrolase. (241 aa)
Hbut_1206Conserved crenarchaeal protein. (160 aa)
Hbut_1205Universally conserved protein. (710 aa)
Hbut_1199Conserved archaeal protein. (216 aa)
rad50Predicted Rad50; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (887 aa)
mre11Predicted DNA repair exonuclease; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. (407 aa)
Hbut_1177Conserved archaeal protein. (566 aa)
Hbut_1174Universally conserved protein. (297 aa)
Hbut_1170Universally conserved protein. (444 aa)
tmcA-3P-loop ATPase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (743 aa)
Hbut_1139Conserved archaeal protein. (200 aa)
tfePredicted transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and dest [...] (173 aa)
Hbut_1123Universally conserved protein. (136 aa)
Hbut_1119Conserved crenarchaeal protein. (333 aa)
taw1Conserved archaeal protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (386 aa)
Hbut_110430S ribosomal protein S25e. (76 aa)
priLConserved archaeal protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (377 aa)
Hbut_1092Conserved archaeal protein. (441 aa)
Hbut_1068Predicted helicase. (939 aa)
Hbut_1067Hypothetical protein. (93 aa)
Hbut_1064Predicted nonsense mRNA decay protein. (350 aa)
Hbut_1039Predicted Endonuclease IV. (283 aa)
pdxSPyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (335 aa)
Hbut_0599Anion permease, ArsB/NhaD. (432 aa)
tmcAPredicted P-loop ATPase fused to an acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (713 aa)
Hbut_0648Metal-dependent hydrolase; Related to alanyl-tRNA synthetase. (188 aa)
rnzMetal-dependent hydrolase of beta lactamase, ElaC; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (302 aa)
Hbut_0681ADP-ribosylglycohydrolase. (256 aa)
Hbut_0689Cobalamin adenosyltransferase. (179 aa)
Hbut_0697Hypothetical protein. (151 aa)
Hbut_0720Methyltransferase. (349 aa)
Hbut_0738Hypothetical protein. (86 aa)
Hbut_0739Hypothetical protein. (144 aa)
Hbut_0756Conserved archaeal protein; Belongs to the UPF0251 family. (121 aa)
Hbut_0775Universally conserved protein. (508 aa)
Hbut_077630S ribosomal protein S26. (96 aa)
atpBV-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (476 aa)
Hbut_0786V-type ATP synthase subunit F. (102 aa)
Hbut_0802NADH oxidase. (469 aa)
Hbut_0806Anion-transporting ATPase. (245 aa)
Hbut_0827Conserved archaeal protein. (139 aa)
Hbut_0839Predicted Histone deacetylase. (357 aa)
Hbut_0845Hypothetical protein. (296 aa)
rpl35ae50S ribosomal protein L35Ae; Belongs to the eukaryotic ribosomal protein eL33 family. (106 aa)
dnaGConserved archaeal protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (426 aa)
Hbut_0896DNA polymerase III. (804 aa)
Hbut_0897Predicted GTPase; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (279 aa)
rfcLReplication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (484 aa)
Hbut_0909Cdc6-2; Involved in regulation of DNA replication. (411 aa)
Hbut_0915Predicted signal peptide. (149 aa)
albADNA/RNA-binding protein Alba 1; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (98 aa)
tbpTATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (202 aa)
tmcA-2Predicted P-loop ATPase fused to an acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (868 aa)
Hbut_0955Hypothetical protein; Similar to ref:NP_341828.1. (182 aa)
top6AType II DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (387 aa)
radADNA repair and recombination protein; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (323 aa)
Hbut_0970Universally conserved protein. (185 aa)
albA-2DNA/RNA-binding protein Alba 1; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (89 aa)
Hbut_0981Universally conserved protein. (189 aa)
Hbut_1010Predicted membrane protein. (277 aa)
Hbut_1022Predicted ABC transporter. (439 aa)
Hbut_1025Hypothetical protein. (93 aa)
rpl21e50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (107 aa)
Hbut_1657Dimethyladenosine transferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (251 aa)
rpl10e50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family. (180 aa)
priSProbable DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer sy [...] (380 aa)
rpl44e50S ribosomal protein L44e; Binds to the 23S rRNA. (95 aa)
Hbut_1638DNA repair and recombination protein radB. (200 aa)
Hbut_1636Conserved archaeal protein. (427 aa)
Hbut_1627Short chain dehydrogenase. (261 aa)
Hbut_1624Hydantoin utilization protein B. (555 aa)
Hbut_1618Hypothetical protein. (215 aa)
rpl150S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (217 aa)
rpl1150S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (168 aa)
ftsYSignal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (312 aa)
rpl18a50S ribosomal protein LX. (87 aa)
rpl31e50S ribosomal protein L31e; Belongs to the eukaryotic ribosomal protein eL31 family. (100 aa)
rps19e30S ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (153 aa)
nep1-2Conserved archaeal protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (230 aa)
Hbut_1589Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase. (385 aa)
Hbut_1584Predicted transcriptional regulator. (142 aa)
rps1030S ribosomal protein S10p; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rps730S ribosomal protein S7p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (202 aa)
rps1230S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa)
rpl30e50S ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family. (112 aa)
Hbut_1569Universally conserved protein; The protein has a PUA domain. (162 aa)
Hbut_1562Predicted GTPase. (375 aa)
Hbut_1558Conserved archaeal protein. (180 aa)
Hbut_1556Conserved crenarchaeal protein. (131 aa)
Hbut_1555Short chain dehydrogenase. (272 aa)
Hbut_15313-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (428 aa)
Hbut_1530Conserved archaeal protein. (97 aa)
Hbut_1529Conserved archaeal protein. (141 aa)
Hbut_15273-hydroxy-3-methylglutaryl CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (351 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (288 aa)
Hbut_1515Cytochrome c biogenesis protein. (523 aa)
satSulfate adenylyltransferase; Belongs to the sulfate adenylyltransferase family. (389 aa)
Hbut_1493Putative MoxR ATPase. (315 aa)
Hbut_14884-hydroxybenzoate polyprenyltransferase. (310 aa)
Hbut_1480Ribosomal protein 10e. (151 aa)
Hbut_1472Hypothetical protein; Similar to ref:NP_148161.1. (216 aa)
Hbut_1468Conserved crenarchaeal protein. (218 aa)
cobBNAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily. (258 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (632 aa)
Hbut_1440Predicted Co/Zn/Cd cation transporter. (287 aa)
Hbut_1375Dehydrogenase. (269 aa)
Hbut_1374Hypothetical protein. (311 aa)
kptARNA:NAD 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (233 aa)
fenEndonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as [...] (350 aa)
Hbut_1355Hypothetical protein. (183 aa)
Hbut_1354Hypothetical protein. (217 aa)
rpl34e50S ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family. (106 aa)
rps550S ribosomal protein S5p; With S4 and S12 plays an important role in translational accuracy. (213 aa)
rpl1850S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (211 aa)
rpl19e50S ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (153 aa)
Hbut_131750S ribosomal protein L32E. (122 aa)
rpl650S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (186 aa)
rps830S ribosomal protein S8p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (133 aa)
rps1430S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (57 aa)
rpl550S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (196 aa)
rps4e30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family. (255 aa)
rpl2450S ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (149 aa)
rpl1450S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (138 aa)
rps1730S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (116 aa)
rpl2950S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (77 aa)
rps330S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (247 aa)
rpl2250S ribosomal protein L22; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (156 aa)
rpl2350S ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (88 aa)
Hbut_130250S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (319 aa)
Hbut_1301Conserved archaeal protein. (280 aa)
Hbut_1254Hypothetical protein; Similar to ref:NP_148310.1. (139 aa)
Hbut_1297Predicted ATPase. (333 aa)
rps1930S ribosomal protein S19p; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (155 aa)
Hbut_1281DNA or RNA helicases of superfamily II. (540 aa)
Hbut_1274DNA polymerase I. (938 aa)
Hbut_1265ATPase. (383 aa)
Hbut_1259Conserved archaeal protein; The protein has a zonk finger domain. (195 aa)
Hbut_1257Predicted Dehydrogenase. (454 aa)
truBPredicted pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (345 aa)
rpl14e50S ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family. (98 aa)
Hbut_0004Conserved crenarchaeal protein - Zn binding domain. (127 aa)
Hbut_0016Dehydrogenase, FixC domain protein; Flavoprotein. (353 aa)
Hbut_0025Polyprenyltransferase family - UbiA; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (302 aa)
Hbut_0030Ribosomal biogenesis protein - Nop56/SIK1. (413 aa)
flpArRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (236 aa)
Hbut_0042Predicted ubiquinone/menaquinone biosynthesis methyl transferase. (239 aa)
ubiXFlavoprotein, 3-polyprenyl-4-hydroxybenzoate decarboxylase, UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (197 aa)
endAGeneral archaeal splicing enzyme; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (181 aa)
Hbut_0064XPD/Rad3 related DNA helicase. (611 aa)
Hbut_0081Conserved protein. (135 aa)
Hbut_0087Putative dehydrogenase (flavoprotein), FixC. (382 aa)
Hbut_0088Methyltransferase. (287 aa)
rpl13e50S ribosomal protein L13e; Belongs to the eukaryotic ribosomal protein eL13 family. (88 aa)
Hbut_0108Dihydroorotate dehydrogenase electron transfer subunit. (257 aa)
Hbut_0112Orotidine-5'-phosphate decarboxylase. (218 aa)
Hbut_0131GTPase or GTP-binding - conserved crenarchaeal protein. (395 aa)
Hbut_0154Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (585 aa)
Hbut_0157Succinate dehydrogenase/fumarate reductase iron-sulfur protein. (307 aa)
Hbut_0192NADH-quinone oxidoreductase chain 14. (482 aa)
Hbut_0196A1pp, Appr-1-p processing enzyme. (199 aa)
hemAglutamyl-tRNAglu reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (411 aa)
Hbut_0223Ribonuclease Z. (245 aa)
Hbut_0230Putative glycerate kinase (GckA). (463 aa)
Hbut_0236Phosphohydrolase - HD superfamily; Has a HD domain. (539 aa)
Hbut_0262Adenylate cyclase, class 2. (193 aa)
Hbut_0265Oxyanion-translocating ATPase, ArsA. (300 aa)
Hbut_0266Predicted EndoIII-related endonuclease. (242 aa)
Hbut_0291Short chain dehydrogenase. (243 aa)
Hbut_0317NADH dehydrogenase. (366 aa)
nep1Conserved uncharacterized protein, Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (230 aa)
Hbut_0367Dual specificity phosphatase, catalytic domain. (275 aa)
Hbut_0395AMMECR1 family protein. (228 aa)
Hbut_0399L asparaginase. (318 aa)
rpl1250S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (127 aa)
Hbut_0420K+ transport, Kef-type, membrane component. (508 aa)
ligATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Can use ATP, ADP and GTP, but not CTP, TTP or NAD(+); Belongs to the ATP-dependent DNA ligase family. (608 aa)
rps3ae30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (215 aa)
rps1530S ribosomal protein S13e. (161 aa)
rps24e30S ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (122 aa)
rps6e30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. (217 aa)
rps8e30S ribosomal protein S8e. (136 aa)
Hbut_0457RNA binding protein, Gar1-type. (116 aa)
tgtAQueuine/archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (527 aa)
Hbut_0474Putative exoribonuclease. (427 aa)
Hbut_0480Predicted nucleotide kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (200 aa)
rps17e30S ribosomal protein S17e; The protein has a longer C terminal than otherwise seen in archaea; Belongs to the eukaryotic ribosomal protein eS17 family. (103 aa)
rbcLRibulose bisphosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (441 aa)
Hbut_0519Sulfide dehydrogenase flavoprotein. (384 aa)
Hbut_0521Conserved uncharacterized protein. (393 aa)
Hbut_0522Universally conserved protein. (476 aa)
rps1330S ribosomal protein S13p; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (151 aa)
rps430S ribosomal protein S4p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (176 aa)
rpl18e50S ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family. (123 aa)
rps930S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (158 aa)
rps230S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (216 aa)
fniIsopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (383 aa)
rps28e30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (81 aa)
rpl24e50S ribosomal protein L24e; Binds to the 23S rRNA. (61 aa)
rpl15e50S ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family. (226 aa)
Hbut_0569Universally conserved uncharacterized protein family UPF0023. (237 aa)
rpl37ae50S ribosomal protein L37Ae; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily. (88 aa)
Hbut_0574Conserved archaeal protein; Probably involved in the biogenesis of the ribosome. (216 aa)
Hbut_0577Predicted phosphoesterase, DHH family. (355 aa)
Hbut_057950S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (57 aa)
Hbut_0586Universally conserved protein. (220 aa)
Hbut_0588Predicted Co/Zn/Cd cation transporter. (372 aa)
Hbut_0590Acyl-CoA hydrolase. (336 aa)
Hbut_0595Cdc6-1; Involved in regulation of DNA replication. (407 aa)
Hbut_0596Predicted hydrolase (HAD superfamily). (236 aa)
Your Current Organism:
Hyperthermus butylicus
NCBI taxonomy Id: 415426
Other names: H. butylicus DSM 5456, Hyperthermus butylicus DSM 5456, Hyperthermus butylicus str. DSM 5456, Hyperthermus butylicus strain DSM 5456
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