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Hbut_0030 Hbut_0030 flpA flpA Hbut_0053 Hbut_0053 Hbut_0072 Hbut_0072 srp19 srp19 rps3ae rps3ae rps24e rps24e Hbut_0440 Hbut_0440 Hbut_0457 Hbut_0457 rps17e rps17e rps4 rps4 rpl7ae rpl7ae rpl24e rpl24e rpl15e rpl15e rnp3 rnp3 rnp2 rnp2 rpl37ae rpl37ae Hbut_0719 Hbut_0719 Hbut_0776 Hbut_0776 rpl35ae rpl35ae pdxS pdxS rps19 rps19 rps3 rps3 rnp1 rnp1 Hbut_1317 Hbut_1317 rpl19e rpl19e rps5 rps5 rpl34e rpl34e truB truB Hbut_1405 Hbut_1405 Hbut_1558 Hbut_1558 rpl30e rpl30e rnp4 rnp4 rps19e rps19e rpl31e rpl31e eif6 eif6 rpl44e rpl44e srp54 srp54
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Hbut_0030Ribosomal biogenesis protein - Nop56/SIK1. (413 aa)
flpArRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (236 aa)
Hbut_0053Translation initiation factor eIF-1/SUI1; Belongs to the SUI1 family. (103 aa)
Hbut_0072RIO-like serine/threonine kinase. (299 aa)
srp19Signal recognition particle 19 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. (103 aa)
rps3ae30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (215 aa)
rps24e30S ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (122 aa)
Hbut_0440Hypothetical protein. (136 aa)
Hbut_0457RNA binding protein, Gar1-type. (116 aa)
rps17e30S ribosomal protein S17e; The protein has a longer C terminal than otherwise seen in archaea; Belongs to the eukaryotic ribosomal protein eS17 family. (103 aa)
rps430S ribosomal protein S4p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (176 aa)
rpl7ae50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (127 aa)
rpl24e50S ribosomal protein L24e; Binds to the 23S rRNA. (61 aa)
rpl15e50S ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family. (226 aa)
rnp3RNase P subunit p30; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (220 aa)
rnp2RNase P, Rpp14 family; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (189 aa)
rpl37ae50S ribosomal protein L37Ae; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily. (88 aa)
Hbut_0719Nucleic acid-binding protein, PIN domain, Zn-ribbon module; Conserved archaeal protein. (196 aa)
Hbut_077630S ribosomal protein S26. (96 aa)
rpl35ae50S ribosomal protein L35Ae; Belongs to the eukaryotic ribosomal protein eL33 family. (106 aa)
pdxSPyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (335 aa)
rps1930S ribosomal protein S19p; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (155 aa)
rps330S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (247 aa)
rnp1Ribonuclease P protein component 1; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (111 aa)
Hbut_131750S ribosomal protein L32E. (122 aa)
rpl19e50S ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (153 aa)
rps550S ribosomal protein S5p; With S4 and S12 plays an important role in translational accuracy. (213 aa)
rpl34e50S ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family. (106 aa)
truBPredicted pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (345 aa)
Hbut_1405Universally conserved protein. (192 aa)
Hbut_1558Conserved archaeal protein. (180 aa)
rpl30e50S ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family. (112 aa)
rnp4Conserved archaeal protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (115 aa)
rps19e30S ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (153 aa)
rpl31e50S ribosomal protein L31e; Belongs to the eukaryotic ribosomal protein eL31 family. (100 aa)
eif6Translation initiation factor 6 (eIF-6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (225 aa)
rpl44e50S ribosomal protein L44e; Binds to the 23S rRNA. (95 aa)
srp54Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (447 aa)
Your Current Organism:
Hyperthermus butylicus
NCBI taxonomy Id: 415426
Other names: H. butylicus DSM 5456, Hyperthermus butylicus DSM 5456, Hyperthermus butylicus str. DSM 5456, Hyperthermus butylicus strain DSM 5456
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