STRINGSTRING
A0A1V6Q1P8 A0A1V6Q1P8 A0A1V6Q1A2 A0A1V6Q1A2 A0A1V6Q165 A0A1V6Q165 A0A1V6Q068 A0A1V6Q068 A0A1V6PZG4 A0A1V6PZG4 A0A1V6PZ28 A0A1V6PZ28 A0A1V6PYV7 A0A1V6PYV7 MCM7 MCM7 A0A1V6PYC6 A0A1V6PYC6 A0A1V6PY61 A0A1V6PY61 A0A1V6PY12 A0A1V6PY12 A0A1V6PXK1 A0A1V6PXK1 A0A1V6PXE1 A0A1V6PXE1 A0A1V6PX23 A0A1V6PX23 A0A1V6PWY9 A0A1V6PWY9 A0A1V6PWW7 A0A1V6PWW7 A0A1V6PWI5 A0A1V6PWI5 A0A1V6PVB2 A0A1V6PVB2 A0A1V6PV87 A0A1V6PV87 A0A1V6PV45 A0A1V6PV45 A0A1V6PUX1 A0A1V6PUX1 FEN1 FEN1 A0A1V6PUQ1 A0A1V6PUQ1 A0A1V6PUH3 A0A1V6PUH3 A0A1V6PUH2 A0A1V6PUH2 A0A1V6PUG2 A0A1V6PUG2 A0A1V6PUB8 A0A1V6PUB8 A0A1V6PTZ2 A0A1V6PTZ2 A0A1V6PS32 A0A1V6PS32 A0A1V6PS12 A0A1V6PS12 A0A1V6PRW8 A0A1V6PRW8 A0A1V6PRT4 A0A1V6PRT4 A0A1V6PRS4 A0A1V6PRS4 A0A1V6PRR9 A0A1V6PRR9 A0A1V6PRK0 A0A1V6PRK0 A0A1V6PR95 A0A1V6PR95 A0A1V6PR85 A0A1V6PR85 A0A1V6PQY6 A0A1V6PQY6 A0A1V6PQ34 A0A1V6PQ34 A0A1V6PPY6 A0A1V6PPY6 A0A1V6PJY6 A0A1V6PJY6 A0A1V6PHH0 A0A1V6PHH0 A0A1V6PBN7 A0A1V6PBN7 A0A1V6QG26 A0A1V6QG26 A0A1V6QI16 A0A1V6QI16 A0A1V6QIA5 A0A1V6QIA5 A0A1V6QIH1 A0A1V6QIH1 A0A1V6QKC6 A0A1V6QKC6 A0A1V6QKM0 A0A1V6QKM0 A0A1V6QKM4 A0A1V6QKM4 A0A1V6QLA1 A0A1V6QLA1 A0A1V6QLC1 A0A1V6QLC1 A0A1V6QN16 A0A1V6QN16 A0A1V6QN19 A0A1V6QN19 A0A1V6QNH1 A0A1V6QNH1 A0A1V6QNM8 A0A1V6QNM8 A0A1V6QNN3 A0A1V6QNN3 A0A1V6QP32 A0A1V6QP32 A0A1V6QP74 A0A1V6QP74 A0A1V6QPN6 A0A1V6QPN6 A0A1V6QF87 A0A1V6QF87 A0A1V6QPT4 A0A1V6QPT4 A0A1V6QQC3 A0A1V6QQC3 A0A1V6QFA2 A0A1V6QFA2 A0A1V6QFS8 A0A1V6QFS8 A0A1V6QEZ6 A0A1V6QEZ6 A0A1V6QEH4 A0A1V6QEH4 A0A1V6QEA5 A0A1V6QEA5 A0A1V6QE53 A0A1V6QE53 A0A1V6QDJ5 A0A1V6QDJ5 A0A1V6QDD8 A0A1V6QDD8 A0A1V6QD54 A0A1V6QD54 A0A1V6QD51 A0A1V6QD51 A0A1V6QCG5 A0A1V6QCG5 A0A1V6QCA4 A0A1V6QCA4 A0A1V6QC09 A0A1V6QC09 A0A1V6QC05 A0A1V6QC05 PIF1 PIF1 A0A1V6QBM9 A0A1V6QBM9 A0A1V6QBI8 A0A1V6QBI8 A0A1V6QBE8 A0A1V6QBE8 A0A1V6QBA9 A0A1V6QBA9 A0A1V6QAS0 A0A1V6QAS0 A0A1V6QA59 A0A1V6QA59 A0A1V6Q985 A0A1V6Q985 A0A1V6Q8N7 A0A1V6Q8N7 A0A1V6Q807 A0A1V6Q807 A0A1V6Q7R1 A0A1V6Q7R1 A0A1V6Q7N6 A0A1V6Q7N6 A0A1V6Q7F6 A0A1V6Q7F6 A0A1V6Q718 A0A1V6Q718 A0A1V6Q6N0 A0A1V6Q6N0 A0A1V6Q6L5 A0A1V6Q6L5 A0A1V6Q6K5 A0A1V6Q6K5 A0A1V6Q5T6 A0A1V6Q5T6 A0A1V6Q5K2 A0A1V6Q5K2 A0A1V6Q5G3 A0A1V6Q5G3 A0A1V6Q5B0 A0A1V6Q5B0 A0A1V6Q596 A0A1V6Q596 A0A1V6Q531 A0A1V6Q531 A0A1V6Q4R2 A0A1V6Q4R2 A0A1V6Q4N2 A0A1V6Q4N2 A0A1V6Q3I4 A0A1V6Q3I4 A0A1V6Q1X4 A0A1V6Q1X4 A0A1V6Q1K1 A0A1V6Q1K1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1V6Q1P8DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1223 aa)
A0A1V6Q1A2MPN domain-containing protein. (1255 aa)
A0A1V6Q165Uncharacterized protein. (542 aa)
A0A1V6Q068Uncharacterized protein. (1911 aa)
A0A1V6PZG4HD domain-containing protein. (229 aa)
A0A1V6PZ28DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (272 aa)
A0A1V6PYV7D-aminoacyl-tRNA deacylase. (195 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (808 aa)
A0A1V6PYC6MRC1 domain-containing protein. (1362 aa)
A0A1V6PY61Uncharacterized protein. (551 aa)
A0A1V6PY12DNA primase; Belongs to the eukaryotic-type primase small subunit family. (501 aa)
A0A1V6PXK1DNA polymerase. (1462 aa)
A0A1V6PXE1AAA domain-containing protein. (352 aa)
A0A1V6PX23Replication factor C subunit 1. (1039 aa)
A0A1V6PWY9DNA ligase. (1001 aa)
A0A1V6PWW7Uncharacterized protein. (679 aa)
A0A1V6PWI5Uncharacterized protein. (253 aa)
A0A1V6PVB2AAA domain-containing protein. (394 aa)
A0A1V6PV87Uncharacterized protein. (2309 aa)
A0A1V6PV45Protein kinase domain-containing protein. (478 aa)
A0A1V6PUX1Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (263 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (385 aa)
A0A1V6PUQ1Uncharacterized protein. (562 aa)
A0A1V6PUH3AAA domain-containing protein. (1043 aa)
A0A1V6PUH2Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (342 aa)
A0A1V6PUG2Uncharacterized protein. (1020 aa)
A0A1V6PUB8FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (571 aa)
A0A1V6PTZ2Uncharacterized protein. (145 aa)
A0A1V6PS32ORC_WH_C domain-containing protein. (697 aa)
A0A1V6PS12DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (211 aa)
A0A1V6PRW8DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (344 aa)
A0A1V6PRT4WD_REPEATS_REGION domain-containing protein. (845 aa)
A0A1V6PRS4RNase H domain-containing protein. (396 aa)
A0A1V6PRR9AAA domain-containing protein. (393 aa)
A0A1V6PRK0Uncharacterized protein. (670 aa)
A0A1V6PR95Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (635 aa)
A0A1V6PR85DNA_pol_E_B domain-containing protein. (760 aa)
A0A1V6PQY6AAA domain-containing protein. (714 aa)
A0A1V6PQ34Uncharacterized protein. (296 aa)
A0A1V6PPY6Sld5 domain-containing protein. (183 aa)
A0A1V6PJY6Uncharacterized protein. (264 aa)
A0A1V6PHH0Uncharacterized protein. (195 aa)
A0A1V6PBN7ATP-dependent DNA helicase; Belongs to the helicase family. (280 aa)
A0A1V6QG26DNA helicase; Belongs to the MCM family. (720 aa)
A0A1V6QI16Uncharacterized protein. (1008 aa)
A0A1V6QIA5Helicase ATP-binding domain-containing protein. (831 aa)
A0A1V6QIH1Uncharacterized protein. (623 aa)
A0A1V6QKC6Uncharacterized protein. (880 aa)
A0A1V6QKM0Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (788 aa)
A0A1V6QKM4DNA helicase; Belongs to the MCM family. (897 aa)
A0A1V6QLA1Uncharacterized protein. (282 aa)
A0A1V6QLC1SLD3 domain-containing protein. (989 aa)
A0A1V6QN16Uncharacterized protein. (103 aa)
A0A1V6QN19DNA ligase. (867 aa)
A0A1V6QNH1Uncharacterized protein. (187 aa)
A0A1V6QNM8Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (687 aa)
A0A1V6QNN3DNA polymerase. (1102 aa)
A0A1V6QP32Uncharacterized protein. (473 aa)
A0A1V6QP74AAA domain-containing protein. (1163 aa)
A0A1V6QPN6RPA_C domain-containing protein. (279 aa)
A0A1V6QF87Sld5 domain-containing protein. (226 aa)
A0A1V6QPT4DNA helicase; Belongs to the MCM family. (996 aa)
A0A1V6QQC3Uncharacterized protein. (396 aa)
A0A1V6QFA2Uncharacterized protein. (197 aa)
A0A1V6QFS8Uncharacterized protein. (534 aa)
A0A1V6QEZ6Sld5 domain-containing protein. (178 aa)
A0A1V6QEH4Uncharacterized protein. (371 aa)
A0A1V6QEA5Uncharacterized protein. (1661 aa)
A0A1V6QE53Cnn_1N domain-containing protein. (985 aa)
A0A1V6QDJ5DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (628 aa)
A0A1V6QDD8Uncharacterized protein. (126 aa)
A0A1V6QD54WD_REPEATS_REGION domain-containing protein. (721 aa)
A0A1V6QD51Uncharacterized protein. (123 aa)
A0A1V6QCG5CBFD_NFYB_HMF domain-containing protein. (187 aa)
A0A1V6QCA4Uncharacterized protein. (419 aa)
A0A1V6QC09Uncharacterized protein. (817 aa)
A0A1V6QC05PUL domain-containing protein. (475 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (716 aa)
A0A1V6QBM9Uncharacterized protein. (805 aa)
A0A1V6QBI8DNA helicase; Belongs to the MCM family. (953 aa)
A0A1V6QBE8DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (654 aa)
A0A1V6QBA9POLAc domain-containing protein. (1094 aa)
A0A1V6QAS0AAA domain-containing protein. (350 aa)
A0A1V6QA59Uncharacterized protein. (633 aa)
A0A1V6Q985DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2229 aa)
A0A1V6Q8N7DNA ligase. (837 aa)
A0A1V6Q807Uncharacterized protein. (177 aa)
A0A1V6Q7R1Rtf2 domain-containing protein. (314 aa)
A0A1V6Q7N6Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (867 aa)
A0A1V6Q7F6Cell division control protein; Belongs to the CDC6/cdc18 family. (636 aa)
A0A1V6Q718HD domain-containing protein. (382 aa)
A0A1V6Q6N0Uncharacterized protein. (849 aa)
A0A1V6Q6L5RNase H domain-containing protein. (304 aa)
A0A1V6Q6K5ERCC4 domain-containing protein. (646 aa)
A0A1V6Q5T6Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (844 aa)
A0A1V6Q5K2Zn(2)-C6 fungal-type domain-containing protein. (706 aa)
A0A1V6Q5G3DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (501 aa)
A0A1V6Q5B0DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (870 aa)
A0A1V6Q596DNA helicase; Belongs to the MCM family. (881 aa)
A0A1V6Q531CPSF_A domain-containing protein. (1247 aa)
A0A1V6Q4R2RNase H domain-containing protein. (321 aa)
A0A1V6Q4N2Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
A0A1V6Q3I4AAA_16 domain-containing protein. (534 aa)
A0A1V6Q1X4DNA polymerase. (1675 aa)
A0A1V6Q1K1UmuC domain-containing protein. (611 aa)
Your Current Organism:
Penicillium antarcticum
NCBI taxonomy Id: 416450
Other names: CBS 100492, FRR 4989, P. antarcticum
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.