28 items (Penicillium antarcticum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	A0A1V6PRW8	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (344 aa)
	A0A1V6PPX7	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1726 aa)
	A0A1V6PR95	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (635 aa)
	A0A1V6QN16	Uncharacterized protein. (103 aa)
	A0A1V6QKC1	DNA_MISMATCH_REPAIR_2 domain-containing protein. (932 aa)
	A0A1V6QJR8	ERCC4 domain-containing protein. (593 aa)
	A0A1V6QI65	Serine/threonine-protein kinase. (1142 aa)
	A0A1V6QHK4	TBPIP domain-containing protein. (214 aa)
	A0A1V6QGG9	TP6A_N domain-containing protein. (345 aa)
	A0A1V6QDJ5	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (628 aa)
	A0A1V6QC96	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1125 aa)
	A0A1V6QBN5	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (634 aa)
	A0A1V6Q6K5	ERCC4 domain-containing protein. (646 aa)
	A0A1V6Q645	Uncharacterized protein. (77 aa)
	A0A1V6Q5N0	Uncharacterized protein. (379 aa)
	A0A1V6Q4I6	DNA_MISMATCH_REPAIR_2 domain-containing protein. (888 aa)
	A0A1V6Q3L0	ERCC4 domain-containing protein. (966 aa)
	A0A1V6Q2T3	Uncharacterized protein; Belongs to the RecA family. (359 aa)
	A0A1V6Q0V0	Uncharacterized protein. (960 aa)
	A0A1V6Q068	Uncharacterized protein. (1911 aa)
	A0A1V6PZZ7	Uncharacterized protein. (831 aa)
	A0A1V6PYE5	DUF1767 domain-containing protein. (238 aa)
	A0A1V6PWU3	DNA_mis_repair domain-containing protein. (833 aa)
	A0A1V6PWC7	Uncharacterized protein. (237 aa)
	A0A1V6PV45	Protein kinase domain-containing protein. (478 aa)
	A0A1V6PUT2	RECA_2 domain-containing protein. (432 aa)
	A0A1V6PTE8	DUF2439 domain-containing protein. (646 aa)
	A0A1V6PSA9	Uncharacterized protein. (281 aa)

Your Current Organism:

Penicillium antarcticum

NCBI taxonomy Id: 416450
Other names: CBS 100492, FRR 4989, P. antarcticum

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V6PPX7	A0A1V6PR95	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.404
A0A1V6PPX7	A0A1V6PRW8	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.652
A0A1V6PPX7	A0A1V6PUT2	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	RECA_2 domain-containing protein.	0.470
A0A1V6PPX7	A0A1V6PWU3	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	DNA_mis_repair domain-containing protein.	0.435
A0A1V6PPX7	A0A1V6PZZ7	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Uncharacterized protein.	0.516
A0A1V6PPX7	A0A1V6Q068	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Uncharacterized protein.	0.485
A0A1V6PPX7	A0A1V6Q0V0	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Uncharacterized protein.	0.516
A0A1V6PPX7	A0A1V6QDJ5	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.505
A0A1V6PPX7	A0A1V6QGG9	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	TP6A_N domain-containing protein.	0.562
A0A1V6PPX7	A0A1V6QI65	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Serine/threonine-protein kinase.	0.656
A0A1V6PPX7	A0A1V6QJR8	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	ERCC4 domain-containing protein.	0.524
A0A1V6PR95	A0A1V6PPX7	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.404
A0A1V6PR95	A0A1V6PRW8	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.989
A0A1V6PR95	A0A1V6PUT2	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	RECA_2 domain-containing protein.	0.966
A0A1V6PR95	A0A1V6PV45	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Protein kinase domain-containing protein.	0.719
A0A1V6PR95	A0A1V6PWU3	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	DNA_mis_repair domain-containing protein.	0.740
A0A1V6PR95	A0A1V6PYE5	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	DUF1767 domain-containing protein.	0.939
A0A1V6PR95	A0A1V6PZZ7	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Uncharacterized protein.	0.700
A0A1V6PR95	A0A1V6Q0V0	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Uncharacterized protein.	0.700
A0A1V6PR95	A0A1V6Q2T3	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Uncharacterized protein; Belongs to the RecA family.	0.927