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MCM7 MCM7 A0A1V6Q596 A0A1V6Q596 A0A1V6QLG2 A0A1V6QLG2 A0A1V6QG26 A0A1V6QG26 A0A1V6QCJ8 A0A1V6QCJ8 A0A1V6Q9H9 A0A1V6Q9H9 A0A1V6PQA7 A0A1V6PQA7 A0A1V6PHE0 A0A1V6PHE0 A0A1V6PTN1 A0A1V6PTN1 A0A1V6PVT4 A0A1V6PVT4 A0A1V6PWT8 A0A1V6PWT8 A0A1V6PY49 A0A1V6PY49 A0A1V6PYQ8 A0A1V6PYQ8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (808 aa)
A0A1V6Q596DNA helicase; Belongs to the MCM family. (881 aa)
A0A1V6QLG2PHD-type domain-containing protein. (841 aa)
A0A1V6QG26DNA helicase; Belongs to the MCM family. (720 aa)
A0A1V6QCJ8CULLIN_2 domain-containing protein; Belongs to the cullin family. (875 aa)
A0A1V6Q9H9Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (354 aa)
A0A1V6PQA7Uncharacterized protein. (245 aa)
A0A1V6PHE0Uncharacterized protein. (610 aa)
A0A1V6PTN1Uncharacterized protein. (1654 aa)
A0A1V6PVT4Stc1 domain-containing protein. (224 aa)
A0A1V6PWT8Uncharacterized protein. (675 aa)
A0A1V6PY49Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (505 aa)
A0A1V6PYQ8Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (511 aa)
Your Current Organism:
Penicillium antarcticum
NCBI taxonomy Id: 416450
Other names: CBS 100492, FRR 4989, P. antarcticum
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