13 items (Penicillium antarcticum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (808 aa)
	A0A1V6Q596	DNA helicase; Belongs to the MCM family. (881 aa)
	A0A1V6QLG2	PHD-type domain-containing protein. (841 aa)
	A0A1V6QG26	DNA helicase; Belongs to the MCM family. (720 aa)
	A0A1V6QCJ8	CULLIN_2 domain-containing protein; Belongs to the cullin family. (875 aa)
	A0A1V6Q9H9	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (354 aa)
	A0A1V6PQA7	Uncharacterized protein. (245 aa)
	A0A1V6PHE0	Uncharacterized protein. (610 aa)
	A0A1V6PTN1	Uncharacterized protein. (1654 aa)
	A0A1V6PVT4	Stc1 domain-containing protein. (224 aa)
	A0A1V6PWT8	Uncharacterized protein. (675 aa)
	A0A1V6PY49	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (505 aa)
	A0A1V6PYQ8	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (511 aa)

Your Current Organism:

Penicillium antarcticum

NCBI taxonomy Id: 416450
Other names: CBS 100492, FRR 4989, P. antarcticum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1V6PHE0	A0A1V6PQA7	A0A1V6PHE0	A0A1V6PQA7	Uncharacterized protein.	Uncharacterized protein.	0.419
A0A1V6PQA7	A0A1V6PHE0	A0A1V6PQA7	A0A1V6PHE0	Uncharacterized protein.	Uncharacterized protein.	0.419
A0A1V6PQA7	A0A1V6PTN1	A0A1V6PQA7	A0A1V6PTN1	Uncharacterized protein.	Uncharacterized protein.	0.634
A0A1V6PQA7	A0A1V6PY49	A0A1V6PQA7	A0A1V6PY49	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.516
A0A1V6PQA7	A0A1V6Q9H9	A0A1V6PQA7	A0A1V6Q9H9	Uncharacterized protein.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.843
A0A1V6PQA7	A0A1V6QLG2	A0A1V6PQA7	A0A1V6QLG2	Uncharacterized protein.	PHD-type domain-containing protein.	0.419
A0A1V6PTN1	A0A1V6PQA7	A0A1V6PTN1	A0A1V6PQA7	Uncharacterized protein.	Uncharacterized protein.	0.634
A0A1V6PTN1	A0A1V6Q9H9	A0A1V6PTN1	A0A1V6Q9H9	Uncharacterized protein.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.461
A0A1V6PTN1	A0A1V6QCJ8	A0A1V6PTN1	A0A1V6QCJ8	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.487
A0A1V6PY49	A0A1V6PQA7	A0A1V6PY49	A0A1V6PQA7	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Uncharacterized protein.	0.516
A0A1V6PY49	A0A1V6Q9H9	A0A1V6PY49	A0A1V6Q9H9	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.590
A0A1V6Q596	A0A1V6QG26	A0A1V6Q596	A0A1V6QG26	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
A0A1V6Q596	MCM7	A0A1V6Q596	A0A1V6PYN2	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
A0A1V6Q9H9	A0A1V6PQA7	A0A1V6Q9H9	A0A1V6PQA7	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.843
A0A1V6Q9H9	A0A1V6PTN1	A0A1V6Q9H9	A0A1V6PTN1	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.461
A0A1V6Q9H9	A0A1V6PY49	A0A1V6Q9H9	A0A1V6PY49	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.590
A0A1V6QCJ8	A0A1V6PTN1	A0A1V6QCJ8	A0A1V6PTN1	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Uncharacterized protein.	0.487
A0A1V6QG26	A0A1V6Q596	A0A1V6QG26	A0A1V6Q596	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
A0A1V6QG26	MCM7	A0A1V6QG26	A0A1V6PYN2	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
A0A1V6QLG2	A0A1V6PQA7	A0A1V6QLG2	A0A1V6PQA7	PHD-type domain-containing protein.	Uncharacterized protein.	0.419