(56 nodes) NADP binding network (Penicillium antarcticum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1V6Q4Z2	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (358 aa)
	A0A1V6Q5Q3	Oxidored_FMN domain-containing protein. (422 aa)
	A0A1V6Q6N9	TauD domain-containing protein. (428 aa)
	A0A1V6Q6S8	Uncharacterized protein. (706 aa)
	A0A1V6Q8A2	PKS_ER domain-containing protein. (389 aa)
	A0A1V6Q780	TauD domain-containing protein. (369 aa)
	A0A1V6P6D3	NAD_binding_2 domain-containing protein. (243 aa)
	A0A1V6PM85	Uncharacterized protein. (371 aa)
	A0A1V6PP94	Uncharacterized protein. (330 aa)
	A0A1V6PQZ4	Uncharacterized protein; Belongs to the FMO family. (575 aa)
	A0A1V6PRF9	PKS_ER domain-containing protein. (398 aa)
	A0A1V6PRJ5	Aldedh domain-containing protein. (458 aa)
	A0A1V6PRS8	Zn(2)-C6 fungal-type domain-containing protein. (1056 aa)
	A0A1V6PS68	Uncharacterized protein. (526 aa)
	A0A1V6PSD9	Uncharacterized protein. (546 aa)
	A0A1V6PSR9	Uncharacterized protein. (587 aa)
	A0A1V6PT17	Glyceraldehyde-3-phosphate dehydrogenase. (336 aa)
	A0A1V6PT52	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (473 aa)
	A0A1V6PVD0	RibD_C domain-containing protein. (621 aa)
	A0A1V6PVK6	Oxidored_FMN domain-containing protein. (420 aa)
	A0A1V6PWN3	PKS_ER domain-containing protein. (330 aa)
	A0A1V6PX22	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (516 aa)
	A0A1V6PX35	Uncharacterized protein. (279 aa)
	A0A1V6QPQ1	Uncharacterized protein. (574 aa)
	A0A1V6QPL6	Uncharacterized protein. (123 aa)
	A0A1V6QNT7	Uncharacterized protein. (546 aa)
	cprA	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (695 aa)
	A0A1V6QNB3	Uncharacterized protein. (638 aa)
	A0A1V6QN92	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (265 aa)
	A0A1V6QN72	Uncharacterized protein. (359 aa)
	A0A1V6QMW7	Uncharacterized protein; Belongs to the FMO family. (491 aa)
	A0A1V6QL65	Uncharacterized protein. (570 aa)
	A0A1V6QKW3	Uncharacterized protein. (615 aa)
	A0A1V6QKP0	Uncharacterized protein. (576 aa)
	A0A1V6QKI9	Homoserine dehydrogenase. (370 aa)
	A0A1V6QIJ5	PKS_ER domain-containing protein. (347 aa)
	A0A1V6QI04	RibD_C domain-containing protein. (278 aa)
	A0A1V6QG84	Uncharacterized protein; Belongs to the FMO family. (487 aa)
	TAH18	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (640 aa)
	A0A1V6QE16	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450. (708 aa)
	A0A1V6PXA0	Uncharacterized protein. (620 aa)
	A0A1V6PXJ4	Oxidored_FMN domain-containing protein. (422 aa)
	A0A1V6PXN6	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (521 aa)
	A0A1V6PZ48	Uncharacterized protein; Belongs to the FMO family. (477 aa)
	A0A1V6Q0S4	Pyr_redox_2 domain-containing protein. (538 aa)
	A0A1V6Q0Z5	PKS_ER domain-containing protein. (345 aa)
	A0A1V6Q250	Semialdhyde_dh domain-containing protein. (364 aa)
	A0A1V6Q323	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (550 aa)
	A0A1V6QD83	Uncharacterized protein. (495 aa)
	A0A1V6Q9Y4	Pyr_redox_2 domain-containing protein. (686 aa)
	A0A1V6Q910	Uncharacterized protein. (541 aa)
	A0A1V6Q331	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (514 aa)
	A0A1V6Q354	Uncharacterized protein. (225 aa)
	A0A1V6Q8E2	Uncharacterized protein. (620 aa)
	A0A1V6Q432	PKS_ER domain-containing protein. (381 aa)
	A0A1V6Q4C6	Uncharacterized protein. (1357 aa)

Your Current Organism:

Penicillium antarcticum

NCBI taxonomy Id: 416450
Other names: CBS 100492, FRR 4989, P. antarcticum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V6PP94	A0A1V6Q323	Uncharacterized protein.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.400
A0A1V6PRJ5	A0A1V6PT17	Aldedh domain-containing protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.444
A0A1V6PRJ5	A0A1V6Q250	Aldedh domain-containing protein.	Semialdhyde_dh domain-containing protein.	0.606
A0A1V6PRJ5	A0A1V6Q4Z2	Aldedh domain-containing protein.	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.444
A0A1V6PRJ5	A0A1V6QKI9	Aldedh domain-containing protein.	Homoserine dehydrogenase.	0.568
A0A1V6PRS8	A0A1V6PWN3	Zn(2)-C6 fungal-type domain-containing protein.	PKS_ER domain-containing protein.	0.442
A0A1V6PT17	A0A1V6PRJ5	Glyceraldehyde-3-phosphate dehydrogenase.	Aldedh domain-containing protein.	0.444
A0A1V6PT17	A0A1V6PT52	Glyceraldehyde-3-phosphate dehydrogenase.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.463
A0A1V6PT17	A0A1V6PVD0	Glyceraldehyde-3-phosphate dehydrogenase.	RibD_C domain-containing protein.	0.585
A0A1V6PT17	A0A1V6PX22	Glyceraldehyde-3-phosphate dehydrogenase.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.476
A0A1V6PT17	A0A1V6PXN6	Glyceraldehyde-3-phosphate dehydrogenase.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.443
A0A1V6PT17	A0A1V6Q250	Glyceraldehyde-3-phosphate dehydrogenase.	Semialdhyde_dh domain-containing protein.	0.839
A0A1V6PT17	A0A1V6Q323	Glyceraldehyde-3-phosphate dehydrogenase.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.968
A0A1V6PT17	A0A1V6Q331	Glyceraldehyde-3-phosphate dehydrogenase.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.639
A0A1V6PT17	A0A1V6Q4Z2	Glyceraldehyde-3-phosphate dehydrogenase.	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.888
A0A1V6PT17	A0A1V6QI04	Glyceraldehyde-3-phosphate dehydrogenase.	RibD_C domain-containing protein.	0.585
A0A1V6PT52	A0A1V6PT17	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.463
A0A1V6PT52	A0A1V6PX22	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.451
A0A1V6PT52	A0A1V6PXN6	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.400
A0A1V6PT52	A0A1V6Q323	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.585