(24 nodes) Riboflavin synthase-like beta-barrel network (Penicillium antarcticum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1V6QE16	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450. (708 aa)
	A0A1V6QAY2	FAD-binding FR-type domain-containing protein. (385 aa)
	A0A1V6Q6T3	Uncharacterized protein. (274 aa)
	A0A1V6Q5S5	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (318 aa)
	A0A1V6Q4F5	Uncharacterized protein. (233 aa)
	A0A1V6Q3I1	FAD-binding FR-type domain-containing protein. (694 aa)
	A0A1V6Q1W1	FAD-binding FR-type domain-containing protein. (842 aa)
	A0A1V6Q1G7	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa)
	A0A1V6PZZ6	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. (863 aa)
	A0A1V6PZM5	FAD-binding FR-type domain-containing protein. (411 aa)
	A0A1V6PZE9	FAD-binding FR-type domain-containing protein. (687 aa)
	A0A1V6PYS6	Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family. (1107 aa)
	A0A1V6PWL8	FAD-binding FR-type domain-containing protein. (644 aa)
	A0A1V6PTD7	FAD-binding FR-type domain-containing protein. (741 aa)
	A0A1V6PSM3	FAD-binding FR-type domain-containing protein. (638 aa)
	A0A1V6PVA7	FAD-binding FR-type domain-containing protein. (1043 aa)
	A0A1V6PU17	FAD-binding FR-type domain-containing protein. (619 aa)
	A0A1V6PSC8	Uncharacterized protein. (468 aa)
	A0A1V6QJN0	FAD-binding FR-type domain-containing protein. (596 aa)
	A0A1V6QIU1	FAD-binding FR-type domain-containing protein. (576 aa)
	TAH18	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (640 aa)
	A0A1V6QJT5	Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family. (1018 aa)
	A0A1V6QKM3	Uncharacterized protein; Belongs to the globin family. (419 aa)
	cprA	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (695 aa)

Your Current Organism:

Penicillium antarcticum

NCBI taxonomy Id: 416450
Other names: CBS 100492, FRR 4989, P. antarcticum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1V6PSC8	A0A1V6PZZ6	A0A1V6PSC8	A0A1V6PZZ6	Uncharacterized protein.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.783
A0A1V6PSC8	A0A1V6Q4F5	A0A1V6PSC8	A0A1V6Q4F5	Uncharacterized protein.	Uncharacterized protein.	0.454
A0A1V6PSC8	A0A1V6Q5S5	A0A1V6PSC8	A0A1V6Q5S5	Uncharacterized protein.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.628
A0A1V6PSC8	A0A1V6QE16	A0A1V6PSC8	A0A1V6QE16	Uncharacterized protein.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450.	0.461
A0A1V6PSC8	cprA	A0A1V6PSC8	A0A1V6QNC7	Uncharacterized protein.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.461
A0A1V6PSM3	A0A1V6PZZ6	A0A1V6PSM3	A0A1V6PZZ6	FAD-binding FR-type domain-containing protein.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.693
A0A1V6PVA7	A0A1V6PZZ6	A0A1V6PVA7	A0A1V6PZZ6	FAD-binding FR-type domain-containing protein.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.899
A0A1V6PWL8	A0A1V6PZZ6	A0A1V6PWL8	A0A1V6PZZ6	FAD-binding FR-type domain-containing protein.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.899
A0A1V6PYS6	A0A1V6PZZ6	A0A1V6PYS6	A0A1V6PZZ6	Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.899
A0A1V6PYS6	A0A1V6QJT5	A0A1V6PYS6	A0A1V6QJT5	Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family.	Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family.	0.850
A0A1V6PZM5	A0A1V6PZZ6	A0A1V6PZM5	A0A1V6PZZ6	FAD-binding FR-type domain-containing protein.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.783
A0A1V6PZM5	A0A1V6Q4F5	A0A1V6PZM5	A0A1V6Q4F5	FAD-binding FR-type domain-containing protein.	Uncharacterized protein.	0.454
A0A1V6PZZ6	A0A1V6PSC8	A0A1V6PZZ6	A0A1V6PSC8	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	Uncharacterized protein.	0.783
A0A1V6PZZ6	A0A1V6PSM3	A0A1V6PZZ6	A0A1V6PSM3	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	FAD-binding FR-type domain-containing protein.	0.693
A0A1V6PZZ6	A0A1V6PVA7	A0A1V6PZZ6	A0A1V6PVA7	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	FAD-binding FR-type domain-containing protein.	0.899
A0A1V6PZZ6	A0A1V6PWL8	A0A1V6PZZ6	A0A1V6PWL8	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	FAD-binding FR-type domain-containing protein.	0.899
A0A1V6PZZ6	A0A1V6PYS6	A0A1V6PZZ6	A0A1V6PYS6	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family.	0.899
A0A1V6PZZ6	A0A1V6PZM5	A0A1V6PZZ6	A0A1V6PZM5	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	FAD-binding FR-type domain-containing protein.	0.783
A0A1V6PZZ6	A0A1V6Q1G7	A0A1V6PZZ6	A0A1V6Q1G7	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.783
A0A1V6PZZ6	A0A1V6Q4F5	A0A1V6PZZ6	A0A1V6Q4F5	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	Uncharacterized protein.	0.483