STRINGSTRING
A0A1V6PW08 A0A1V6PW08 A0A1V6Q0B8 A0A1V6Q0B8 A0A1V6PSW2 A0A1V6PSW2 A0A1V6PUB8 A0A1V6PUB8 A0A1V6PVC3 A0A1V6PVC3 A0A1V6QJ65 A0A1V6QJ65 A0A1V6QIP8 A0A1V6QIP8 A0A1V6QBY3 A0A1V6QBY3 A0A1V6QBQ1 A0A1V6QBQ1 A0A1V6QAM1 A0A1V6QAM1 A0A1V6Q1E9 A0A1V6Q1E9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1V6PW08H15 domain-containing protein. (222 aa)
A0A1V6Q0B8Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1200 aa)
A0A1V6PSW2Histone H2A; Belongs to the histone H2A family. (138 aa)
A0A1V6PUB8FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (571 aa)
A0A1V6PVC3CENP-T_C domain-containing protein. (464 aa)
A0A1V6QJ65Histone H2B; Belongs to the histone H2B family. (141 aa)
A0A1V6QIP8Histone H2A; Belongs to the histone H2A family. (132 aa)
A0A1V6QBY3Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2912 aa)
A0A1V6QBQ1Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1219 aa)
A0A1V6QAM1Histone domain-containing protein. (161 aa)
A0A1V6Q1E9Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
Your Current Organism:
Penicillium antarcticum
NCBI taxonomy Id: 416450
Other names: CBS 100492, FRR 4989, P. antarcticum
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