7 items (Penicillium antarcticum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	A0A1V6Q9I2	Uncharacterized protein. (691 aa)
	A0A1V6Q021	Uncharacterized protein. (686 aa)
	A0A1V6QPE8	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (518 aa)
	A0A1V6PXB3	Pyruvate carboxyltransferase domain-containing protein. (358 aa)
	A0A1V6PTW2	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (539 aa)
	A0A1V6PRI6	Uncharacterized protein. (459 aa)
	A0A1V6QCW7	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (458 aa)

Your Current Organism:

Penicillium antarcticum

NCBI taxonomy Id: 416450
Other names: CBS 100492, FRR 4989, P. antarcticum

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V6PRI6	A0A1V6PTW2	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.685
A0A1V6PRI6	A0A1V6PXB3	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein.	0.723
A0A1V6PRI6	A0A1V6QPE8	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.685
A0A1V6PTW2	A0A1V6PRI6	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Uncharacterized protein.	0.685
A0A1V6PTW2	A0A1V6PXB3	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Pyruvate carboxyltransferase domain-containing protein.	0.943
A0A1V6PTW2	A0A1V6Q021	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Uncharacterized protein.	0.904
A0A1V6PTW2	A0A1V6Q9I2	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Uncharacterized protein.	0.904
A0A1V6PTW2	A0A1V6QCW7	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.924
A0A1V6PTW2	A0A1V6QPE8	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.887
A0A1V6PXB3	A0A1V6PRI6	Pyruvate carboxyltransferase domain-containing protein.	Uncharacterized protein.	0.723
A0A1V6PXB3	A0A1V6PTW2	Pyruvate carboxyltransferase domain-containing protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.943
A0A1V6PXB3	A0A1V6Q021	Pyruvate carboxyltransferase domain-containing protein.	Uncharacterized protein.	0.901
A0A1V6PXB3	A0A1V6Q9I2	Pyruvate carboxyltransferase domain-containing protein.	Uncharacterized protein.	0.901
A0A1V6PXB3	A0A1V6QCW7	Pyruvate carboxyltransferase domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.938
A0A1V6PXB3	A0A1V6QPE8	Pyruvate carboxyltransferase domain-containing protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.943
A0A1V6Q021	A0A1V6PTW2	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.904
A0A1V6Q021	A0A1V6PXB3	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein.	0.901
A0A1V6Q021	A0A1V6Q9I2	Uncharacterized protein.	Uncharacterized protein.	0.892
A0A1V6Q021	A0A1V6QCW7	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.915
A0A1V6Q021	A0A1V6QPE8	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.904