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| | gpsA | Glycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: tma:TM0378 glycerol-3-phosphate dehydrogenase. (336 aa) |
| | Tlet_0012 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: tma:TM0206 hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (170 aa) |
| | Tlet_0030 | Flavodoxin-like protein; KEGG: cdf:CD1679 putative flavodoxin. (157 aa) |
| | Tlet_0048 | PFAM: carbohydrate kinase FGGY; KEGG: lac:LBA0354 gluconate kinase. (480 aa) |
| | Tlet_0049 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: tma:TM0327 phosphoglycerate dehydrogenase, putative. (324 aa) |
| | Tlet_0060 | PFAM: Transketolase domain protein; Transketolase central region; KEGG: tma:TM1762 transketolase. (629 aa) |
| | Tlet_0104 | PFAM: ROK family protein; KEGG: sth:STH602 putative glucose kinase. (293 aa) |
| | Tlet_0139 | TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: ter:Tery_5016 glycogen debranching enzyme GlgX; Belongs to the glycosyl hydrolase 13 family. (713 aa) |
| | Tlet_0147 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: tma:TM1873 ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (376 aa) |
| | Tlet_0180 | PFAM: iron-containing alcohol dehydrogenase; KEGG: tma:TM0111 alcohol dehydrogenase, iron-containing. (385 aa) |
| | Tlet_0193 | PFAM: glucose-6-phosphate isomerase; KEGG: pab:PAB1199 glucose-6-phosphate isomerase. (176 aa) |
| | Tlet_0220 | PFAM: ROK family protein; KEGG: det:DET0049 ROK family protein. (291 aa) |
| | Tlet_0255 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: dsy:DSY4430 hypothetical protein. (315 aa) |
| | apgM | Phosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (402 aa) |
| | Tlet_0281 | TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase; KEGG: tma:TM0239 glucose-1-phosphate adenylyltransferase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (368 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (420 aa) |
| | Tlet_0297 | PFAM: aminotransferase class I and II; KEGG: tma:TM1255 aspartate aminotransferase. (379 aa) |
| | Tlet_0303 | TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: Nucleotidyl transferase; KEGG: tma:TM0862 glucose-1-phosphate thymidylyltransferase. (355 aa) |
| | Tlet_0312 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: tma:TM0381 dihydrolipoamide dehydrogenase. (451 aa) |
| | Tlet_0325 | PFAM: Polyprenyl synthetase; KEGG: tma:TM0161 geranyltranstransferase; Belongs to the FPP/GGPP synthase family. (276 aa) |
| | Tlet_0327 | TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; KEGG: tma:TM1693 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (244 aa) |
| | Tlet_0343 | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; KEGG: tma:TM1080 ribose 5-phosphate isomerase B. (145 aa) |
| | Tlet_0355 | PFAM: glycoside hydrolase family 3 domain protein; KEGG: tma:TM0076 beta-glucosidase. (779 aa) |
| | Tlet_0356 | PFAM: Acetyl xylan esterase; KEGG: tma:TM0077 acetylxylan esterase. (326 aa) |
| | argG | PFAM: argininosuccinate synthase; KEGG: tma:TM1780 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (425 aa) |
| | Tlet_0364 | PFAM: fumarate lyase; KEGG: tma:TM1781 argininosuccinate lyase. (398 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (341 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (395 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (279 aa) |
| | argD | TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: tma:TM1785 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (396 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (265 aa) |
| | Tlet_0421 | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tma:TM1640 glutamate synthase (NADPH) small chain. (471 aa) |
| | Tlet_0430 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: tma:TM0798 malonyl CoA-acyl carrier protein transacylase. (301 aa) |
| | Tlet_0434 | Hypothetical protein; KEGG: chy:CHY_1349 phosphofructokinase. (268 aa) |
| | Tlet_0439 | PFAM: Heptaprenyl diphosphate synthase component I; KEGG: tma:TM1555 hypothetical protein. (191 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa) |
| | Tlet_0460 | Cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: tvo:TVN0174 cystathionine gamma-lyase. (378 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa) |
| | Tlet_0495 | PFAM: aminotransferase class I and II; KEGG: tma:TM1698 aspartate aminotransferase. (399 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (163 aa) |
| | Tlet_0569 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: pfu:PF0753 2-oxoglutarate ferredoxin oxidoreductase, beta subunit. (284 aa) |
| | Tlet_0570 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tma:TM1164 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit. (564 aa) |
| | adk | Nucleoside-triphosphate--adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (217 aa) |
| | Tlet_0610 | TIGRFAM: putative glucokinase, ROK family; PFAM: ROK family protein; ATPase BadF/BadG/BcrA/BcrD type; KEGG: tma:TM1469 glucokinase. (316 aa) |
| | Tlet_0653 | IMP cyclohydrolase; PFAM: MGS domain protein; KEGG: cth:Cthe_1246 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (188 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (345 aa) |
| | dxr | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (359 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (95 aa) |
| | Tlet_0682 | PFAM: mannose-6-phosphate isomerase type I; KEGG: tma:TM0736 mannose-6-phosphate isomerase. (284 aa) |
| | surE | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (259 aa) |
| | Tlet_0713 | PFAM: metallophosphoesterase; KEGG: hpy:HP0104 2',3'-cyclic-nucleotide 2'-phosphodiesterase (CpdB). (284 aa) |
| | Tlet_0719 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (273 aa) |
| | Tlet_0731 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: tma:TM1518 aspartokinase II; Belongs to the aspartokinase family. (398 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (215 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | Tlet_0748 | PFAM: diacylglycerol kinase; KEGG: tma:TM0407 diacylglycerol kinase. (159 aa) |
| | Tlet_0749 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: tma:TM0406 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit. (200 aa) |
| | Tlet_0750 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: tma:TM0405 2-oxoglutarate ferredoxin oxidoreductase, beta subunit. (274 aa) |
| | Tlet_0762 | TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: mpa:MAP2692 fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase. (338 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (314 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (396 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (441 aa) |
| | Tlet_0841 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (367 aa) |
| | Tlet_0870 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: tma:TM1878 UDP-sugar hydrolase; Belongs to the 5'-nucleotidase family. (515 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (115 aa) |
| | Tlet_0874 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (467 aa) |
| | Tlet_0917 | TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: tma:TM0541 fumarate hydratase beta subunit. (161 aa) |
| | Tlet_0918 | TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; KEGG: tma:TM0540 fumarate hydratase alpha subunit. (282 aa) |
| | Tlet_0921 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tma:TM0879 ferredoxin. (75 aa) |
| | Tlet_0922 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tma:TM0878 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit. (386 aa) |
| | Tlet_0937 | PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: tma:TM0769 phosphomannomutase. (479 aa) |
| | Tlet_0944 | TIGRFAM: ornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: ava:Ava_B0165 ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (411 aa) |
| | Tlet_0973 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: tma:TM0665 cysteine synthase. (292 aa) |
| | Tlet_0974 | TIGRFAM: serine O-acetyltransferase; KEGG: tma:TM0666 serine acetyltransferase. (208 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (241 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: tma:TM0689 phosphoglycerate kinase / triose-phosphate isomerase; Belongs to the phosphoglycerate kinase family. (397 aa) |
| | Tlet_0998 | TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: tma:TM0688 glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa) |
| | Tlet_1036 | Beta-glucosidase; PFAM: glycoside hydrolase family 3 domain protein; KEGG: tma:TM0025 beta-glucosidase. (910 aa) |
| | Tlet_1058 | PFAM: aminotransferase class IV; KEGG: tma:TM0831 branched-chain amino acid aminotransferase. (278 aa) |
| | Tlet_1069 | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa) |
| | Tlet_1094 | PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: tma:TM1432 glycerol-3-phosphate dehydrogenase. (479 aa) |
| | Tlet_1113 | PFAM: fumarate lyase; KEGG: atc:AGR_L_463 argininosuccinate lyase (arginosuccinase) (ASAL); Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. (479 aa) |
| | tal | Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa) |
| | katG | Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (726 aa) |
| | Tlet_1230 | PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: shn:Shewana3_2311 alpha amylase, catalytic region. (529 aa) |
| | Tlet_1241 | PFAM: aminotransferase class I and II; KEGG: pho:PH0377 putative histidinol-phosphate aminotransferase. (349 aa) |
| | ldh | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (312 aa) |
| | Tlet_1262 | TIGRFAM: pullulanase, type I; PFAM: glycoside hydrolase family 13 domain protein; pullanase-associated protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: tma:TM1845 pullulanase; Belongs to the glycosyl hydrolase 13 family. (842 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (382 aa) |
| | Tlet_1288 | PFAM: alanine racemase domain protein; KEGG: tma:TM1597 hypothetical protein. (356 aa) |
| | Tlet_1329 | PFAM: Transketolase domain protein; KEGG: tma:TM0954 transketolase, N-terminal subunit. (277 aa) |
| | Tlet_1330 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: tma:TM0953 transketolase, C-terminal subunit. (322 aa) |
| | Tlet_1360 | TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; KEGG: mja:MJ0205 aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (339 aa) |
| | Tlet_1364 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: mka:MK0109 aspartokinase; Belongs to the aspartokinase family. (450 aa) |
| | Tlet_1365 | PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: tma:TM0268 5-methyltetrahydrofolate S-homocysteine methyltransferase. (773 aa) |
| | Tlet_1380 | TIGRFAM: cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; cytidylyltransferase; KEGG: tma:TM0857 riboflavin kinase / FMN adenylyltransferase. (247 aa) |
| | glgA | Glycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (486 aa) |
| | Tlet_1413 | TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: tma:TM0272 pyruvate,orthophosphate dikinase; Belongs to the PEP-utilizing enzyme family. (882 aa) |
| | Tlet_1457 | PFAM: FAD dependent oxidoreductase; Malate:quinone-oxidoreductase; transport-associated; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: tde:TDE0134 oxidoreductase, FAD-dependent. (566 aa) |
| | Tlet_1461 | Succinate--CoA ligase (ADP-forming); PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; KEGG: mja:MJ0210 succinyl-CoA synthetase beta chain. (358 aa) |
| | Tlet_1462 | PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: hbu:Hbut_0202 succinyl-CoA synthetase alpha chain. (278 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (275 aa) |
| | Tlet_1557 | TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: fnu:FN0495 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa) |
| | ispH | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (278 aa) |
| | plsY | Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (199 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: tma:TM1385 glucose-6-phosphate isomerase; Belongs to the GPI family. (451 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (281 aa) |
| | Tlet_1682 | PFAM: Transketolase domain protein; KEGG: bja:blr2168 putative transketolase alpha subunit protein. (302 aa) |
| | Tlet_1683 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: msm:MSMEG_2166 transketoloase, C half. (333 aa) |
| | Tlet_1684 | PFAM: ribulose bisphosphate carboxylase large chain; KEGG: rpc:RPC_2184 ribulose 1 5-bisphosphate carboxylase large subunit-like. (376 aa) |
| | Tlet_1694 | PFAM: FAD linked oxidase domain protein; KEGG: tte:TTE0224 FAD/FMN-containing dehydrogenases. (464 aa) |
| | Tlet_1697 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: tte:TTE1946 glyoxylate reductase. (327 aa) |
| | Tlet_1711 | TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; KEGG: chy:CHY_0128 fructose-1,6-bisphosphate aldolase, class II. (280 aa) |
| | Tlet_1717 | PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: aba:Acid345_2336 Fe-S protein, radical SAM family. (439 aa) |
| | Tlet_1722 | PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: tma:TM1537 Mg-protoporphyrin IX monomethyl ester oxidative cyclase-related protein. (443 aa) |
| | Tlet_1724 | Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: tma:TM1585 glycerate kinase, putative. (412 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (313 aa) |
| | Tlet_1732 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tma:TM1095 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (428 aa) |
| | Tlet_1739 | PFAM: inositol monophosphatase; KEGG: tma:TM1415 putative myo-inositol-1(or 4)-monophosphatase. (255 aa) |
| | Tlet_1758 | TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: swo:Swol_1398 2-oxoglutarate oxidoreductase gamma subunit. (179 aa) |
| | Tlet_1759 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: swo:Swol_1399 putative keto/oxoacid ferredoxin oxidoreductase, beta subunit. (250 aa) |
| | Tlet_1760 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tma:TM1759 2-oxoisovalerate ferredoxin oxidoreductase, alpha subunit. (350 aa) |
| | Tlet_1761 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tma:TM1758 2-oxoisovalerate ferredoxin oxidoreductase, delta subunit. (76 aa) |
| | Tlet_1766 | Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: tma:TM1131 aminotransferase, putative. (412 aa) |
| | Tlet_1768 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: tma:TM1401 D-3-phosphoglycerate dehydrogenase. (303 aa) |
| | Tlet_1774 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: tma:TM0018 pyruvate ferredoxin oxidoreductase, beta subunit. (324 aa) |
| | Tlet_1775 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tma:TM0017 pyruvate ferredoxin oxidoreductase, alpha subunit. (390 aa) |
| | Tlet_1776 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tma:TM0016 pyruvate ferredoxin oxidoreductase, delta subunit. (100 aa) |
| | Tlet_1777 | TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: tma:TM0015 pyruvate ferredoxin oxidoreductase, gamma subunit. (190 aa) |
| | Tlet_1778 | PFAM: glycoside hydrolase family 57; Domain of unknown function DUF1957; KEGG: ter:Tery_0045 glycoside hydrolase, family 57; Belongs to the glycosyl hydrolase 57 family. (527 aa) |
| | acpP-2 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (79 aa) |
| | Tlet_1794 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (224 aa) |
| | Tlet_1795 | PFAM: phosphatidate cytidylyltransferase; KEGG: tma:TM1397 phosphatidate cytidylyltransferase; Belongs to the CDS family. (272 aa) |
| | Tlet_1800 | Hypothetical protein; KEGG: afu:AF0748 A. fulgidus predicted coding region AF0748. (332 aa) |
| | Tlet_1809 | PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: mbu:Mbur_2001 predicted phospho-2-dehydro-3-deoxyheptonate aldolase. (247 aa) |
| | Tlet_1831 | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: tte:TTE0545 Acyl-CoA dehydrogenases. (379 aa) |
| | Tlet_1855 | PFAM: ribulose-phosphate 3-epimerase; KEGG: tma:TM1718 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (216 aa) |
| | Tlet_1859 | PFAM: aminotransferase class I and II; KEGG: cac:CAC2970 PLP-dependent aminotransferase. (391 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa) |
| | Tlet_1879 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mja:MJ0033 succinate dehydrogenase flavoprotein subunit. (593 aa) |
| | trpB | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (422 aa) |
| | Tlet_1891 | TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II; KEGG: cth:Cthe_0349 fructose-1,6-bisphosphate aldolase, class II. (309 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (328 aa) |
| | purD | TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; ATP-grasp domain protein; KEGG: tte:TTE0593 phosphoribosylamine--glycine ligase; Belongs to the GARS family. (415 aa) |
| | purH | TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: bca:BCE_0327 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (506 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (206 aa) |
| | purM | TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: tte:TTE0590 Phosphoribosylaminoimidazol (AIR) synthetase. (337 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (463 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (724 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (234 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (84 aa) |
| | purC | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; KEGG: tte:TTE0588 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase. (232 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (161 aa) |
| | Tlet_1942 | Threonine aldolase; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: chy:CHY_0904 low-specificity L-threonine aldolase. (338 aa) |
| | Tlet_1944 | TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain; KEGG: mta:Moth_1946 L-serine dehydratase, iron-sulfur-dependent, alpha subunit. (293 aa) |
| | Tlet_1945 | TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: serine dehydratase beta chain; KEGG: chy:CHY_2458 L-serine dehydratase, iron-sulfur-dependent, beta subunit. (222 aa) |
| | Tlet_1946 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (336 aa) |
| | dapH | Tetrahydrodipicolinate succinyltransferase domain protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (245 aa) |
| | Tlet_1949 | PFAM: diaminopimelate epimerase; KEGG: tma:TM1522 diaminopimelate epimerase; Belongs to the diaminopimelate epimerase family. (240 aa) |
| | pfp | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (420 aa) |
| | gcvPB | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (479 aa) |
| | gcvPA | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (443 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (362 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa) |
| | Tlet_1962 | TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: tma:TM0208 pyruvate kinase; Belongs to the pyruvate kinase family. (472 aa) |
| | dxs | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (619 aa) |
| | Tlet_2048 | PFAM: inositol monophosphatase; KEGG: ade:Adeh_3387 inositol-1(or 4)-monophosphatase. (255 aa) |
