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pdhD pdhD pdhC pdhC pdhB pdhB pdhA pdhA llmg_0117 llmg_0117 bglS bglS pgk pgk fbp fbp pmg pmg ldhB ldhB bglA bglA nifJ nifJ llmg_0453 llmg_0453 llmg_0475 llmg_0475 gapA gapA enoA enoA fadD fadD ascB ascB llmg_0955 llmg_0955 llmg_0959 llmg_0959 llmg_0960 llmg_0960 bglH bglH pfk pfk pyk pyk ldh ldh tpiA tpiA ldhX ldhX bglA2 bglA2 llmg_1738 llmg_1738 llmg_1894 llmg_1894 adhA adhA fbaA fbaA galM galM glk glk adhE adhE pgiA pgiA gapB gapB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pdhDPyruvate dehydrogenase complex E3 component; lipoamide_DH: dihydrolipoamide dehydrogenase; High confidence in function and specificity. (472 aa)
pdhCDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, PDHac_trf_long: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; High confidence in function and specificity. (530 aa)
pdhBPyruvate dehydrogenase E1 component beta subunit; 1-deoxy-D-xylulose-5-phosphate synthase (DXP synthase); High confidence in function and specificity. (326 aa)
pdhA[EC:1.2.4.1], Pyruvate dehydrogenase E1 component alpha subunit type II, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A) (Fragment)., Dehydrogenase, E1 component, Dehydrogenase E1 component; High confidence in function and specificity. (374 aa)
llmg_0117Hypothetical protein; Putative hydrolase (HAD superfamily) (PFAM), Haloacid dehalogenase-like hydrolase; Conserved hypothetical protein. (207 aa)
bglSBeta-glucosidase, Gentiobiase; Cellobiase; Beta-D-glucoside glucohydrolase; Amygdalase, Glycoside hydrolase, family 1; High confidence in function and specificity; Belongs to the glycosyl hydrolase 1 family. (478 aa)
pgkPhosphoglycerate kinase; High confidence in function and specificity; Belongs to the phosphoglycerate kinase family. (398 aa)
fbpFructose-bisphosphatase; High confidence in function and specificity. (640 aa)
pmgPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (233 aa)
ldhBL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (314 aa)
bglA6-phospho-beta-glucosidase; Glycoside hydrolase, family 1; High confidence in function and specificity; Belongs to the glycosyl hydrolase 1 family. (478 aa)
nifJNifJ protein; Pyruvate:ferredoxin (flavodoxin) oxidoreductase, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain, pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase; High confidence in function and specificity. (1223 aa)
llmg_0453Similar to sucrose-specific PTS enzyme IIABC; PTS system likely trehalose specific; High confidence in function and specificity. (161 aa)
llmg_0475Malate/lactate dehydrogenase; Similar to ldhB; Specificity unclear; Belongs to the LDH/MDH superfamily. (304 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase, type I; High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
enoAEnoA protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (433 aa)
fadDLong-chain acyl-CoA synthetase; Acetyl-coenzyme A synthetase; High confidence in function and specificity. (507 aa)
ascB6-phospho-beta-glucosidase; Glycosyl hydrolase, family 1; High confidence in function and specificity; Belongs to the glycosyl hydrolase 1 family. (477 aa)
llmg_0955PF00107.12: Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity. (348 aa)
llmg_0959Beta-glucosidase; Specificity unclear; Belongs to the glycosyl hydrolase 1 family. (184 aa)
llmg_0960Beta-glucosidase; High confidence in function and specificity; Belongs to the glycosyl hydrolase 1 family. (160 aa)
bglHBeta-glucosidase; High confidence in function and specificity; Belongs to the glycosyl hydrolase 1 family. (478 aa)
pfkPfk protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (340 aa)
pykPyk protein; High confidence in function and specificity; Belongs to the pyruvate kinase family. (502 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (325 aa)
tpiATpiA protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa)
ldhXL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (323 aa)
bglA26-phospho-beta-glucosidase; Glycoside hydrolase, family 1; High confidence in function and specificity; Belongs to the glycosyl hydrolase 1 family. (480 aa)
llmg_1738Beta-glucosidase; High confidence in function and specificity; Belongs to the glycosyl hydrolase 1 family. (453 aa)
llmg_1894Similar to phosphoglycerate/bisphosphoglycerate mutases; High confidence in function and specificity. (193 aa)
adhAZinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity. (340 aa)
fbaAPseudogene; Transposase for insertion sequence element IS905M, contains a stop codon at position 606; Conserved hypothetical protein. (298 aa)
galMAldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (339 aa)
glkGlucokinase; PF00480: ROK family, TIGR00744: ROK family protein (putative glucokinase); High confidence in function and specificity. (323 aa)
adhEPF00465.7: Iron-containing alcohol dehydrogenase; High confidence in function and specificity; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (903 aa)
pgiAPgiA protein; PF00342: Phosphoglucose isomerase; High confidence in function and specificity; Belongs to the GPI family. (448 aa)
gapBTIGR01534: Glyceraldehyde-3-phosphate dehydrogenase, type I, PF02800: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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