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glf1 glf1 llmg_0247 llmg_0247 murA1 murA1 femD femD llmg_0453 llmg_0453 nagZ nagZ murA2 murA2 ptnD ptnD ptnC ptnC ptnAB ptnAB nagB nagB scrK scrK galU galU nagA nagA nanE nanE llmg_1320 llmg_1320 murB murB murQ murQ glmS glmS llmg_1608 llmg_1608 ugd ugd pmi pmi glgD glgD glgC glgC llmg_2003 llmg_2003 glmU glmU chiC chiC galE galE galT galT galK galK glk glk pgiA pgiA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glf1Glf1 protein; High confidence in function and specificity. (376 aa)
llmg_0247Putative UDP-glucose 4-epimerase; Function unclear. (279 aa)
murA1UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (420 aa)
femDPutative phospho-sugar mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (452 aa)
llmg_0453Similar to sucrose-specific PTS enzyme IIABC; PTS system likely trehalose specific; High confidence in function and specificity. (161 aa)
nagZPutative beta-N-acetylglucosaminidase; High confidence in function and specificity. (406 aa)
murA2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (426 aa)
ptnDEIID-AGA: PTS system, mannose/fructose/sorbose family, IID component; High confidence in function and specificity. (307 aa)
ptnCEII-Sor: PTS system, mannose/fructose/sorbose family, IIC component; High confidence in function and specificity. (270 aa)
ptnABPTS system, mannose-specific IIAB components; Pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component; High confidence in function and specificity. (329 aa)
nagBGlucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (235 aa)
scrKFructokinase; High confidence in function and specificity. (291 aa)
galUUDP--glucose-1-phosphate uridylyltransferase; High confidence in function and specificity. (313 aa)
nagANagA protein; High confidence in function and specificity. (382 aa)
nanEPutative N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (234 aa)
llmg_1320Putative xylan beta-1,4-xylosidase; Pseudogene; Conserved hypothetical protein; Belongs to the glycosyl hydrolase 43 family. (461 aa)
murBMurB protein; Cell wall formation. (299 aa)
murQConserved hypothetical protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (297 aa)
glmSGlucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (605 aa)
llmg_1608Putative glycosyl hydrolases; Similar to xylosidases/arabinosidases; Function unclear; Belongs to the glycosyl hydrolase 43 family. (333 aa)
ugdUDP-glucose 6-dehydrogenase; High confidence in function and specificity. (389 aa)
pmiMannose-6-phosphate isomerase; High confidence in function and specificity; Belongs to the mannose-6-phosphate isomerase type 1 family. (315 aa)
glgDGlucose-1-phosphate adenylyltransferase; High confidence in function and specificity. (379 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (380 aa)
llmg_2003UDP-glucose 4-epimerase; High confidence in function and specificity. (189 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the t [...] (458 aa)
chiCAcidic endochitinase precursor (EC 3.2.1.14); Chitinase II, Glycosyl hydrolases family 18; Conserved hypothetical protein. (492 aa)
galEGalE protein; NAD dependent epimerase/dehydratase family; High confidence in function and specificity; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (326 aa)
galTUDP-glucose--hexose-1-phosphate uridylyltransferase; High confidence in function and specificity. (493 aa)
galKGalK protein; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (399 aa)
glkGlucokinase; PF00480: ROK family, TIGR00744: ROK family protein (putative glucokinase); High confidence in function and specificity. (323 aa)
pgiAPgiA protein; PF00342: Phosphoglucose isomerase; High confidence in function and specificity; Belongs to the GPI family. (448 aa)
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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