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dnaN | Beta subunit of DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation [...] (380 aa) | ||||
recO | DNA repair protein recO; Involved in DNA repair and RecF pathway recombination. (251 aa) | ||||
recR | Recombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (198 aa) | ||||
recA | Recombination protein A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (387 aa) | ||||
ssbA | Helix-destabilizing protein, Nucleic acid-binding OB-fold; High confidence in function and specificity. (129 aa) | ||||
holB | holB: DNA polymerase III, delta prime subunit; High confidence in function and specificity. (286 aa) | ||||
dnaE | DNA polymerase III alpha subunit; High confidence in function and specificity. (1070 aa) | ||||
recJ | Single strand DNA-specific exonuclease; DHH family; High confidence in function and specificity. (742 aa) | ||||
holA | Putative DNA polymerase III, delta subunit; High confidence in function and specificity. (334 aa) | ||||
dnaQ | DNA polymerase III, epsilon chain; High confidence in function and specificity. (277 aa) | ||||
recD | Exodeoxyribonuclease V alpha chain; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (833 aa) | ||||
ps416 | Single-strand binding protein ssB; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (141 aa) | ||||
priA | Primosomal protein N' (Replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (781 aa) | ||||
recF | DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (359 aa) | ||||
polC | DNA polymerase III alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1635 aa) | ||||
polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. (877 aa) | ||||
ssbB | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (166 aa) | ||||
dnaX | DNA polymerase III subunits gamma / tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (553 aa) | ||||
ruvB | Holliday junction DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (333 aa) | ||||
ruvA | Holliday junction DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (197 aa) | ||||
recG | ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (666 aa) |