(6 nodes) MCM domain network (Lomentospora prolificans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	jhhlp_006622	DNA helicase; Belongs to the MCM family. (721 aa)
	jhhlp_007697	DNA helicase; Belongs to the MCM family. (1122 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (814 aa)
	jhhlp_006101	DNA helicase; Belongs to the MCM family. (865 aa)
	jhhlp_003351	DNA helicase; Belongs to the MCM family. (893 aa)
	jhhlp_001335	DNA helicase; Belongs to the MCM family. (1021 aa)

Your Current Organism:

Lomentospora prolificans

NCBI taxonomy Id: 41688
Other names: CBS 467.74, IMI 188615, L. prolificans, MUCL 18141, Scedosporium inflatum, Scedosporium prolificans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	jhhlp_001335	A0A2N3N1K1	A0A2N3NHV1	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	jhhlp_003351	A0A2N3N1K1	A0A2N3NGJ5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	jhhlp_006101	A0A2N3N1K1	A0A2N3N4Z3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	jhhlp_006622	A0A2N3N1K1	A0A2N3N6D5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	jhhlp_007697	A0A2N3N1K1	A0A2N3N0A8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
jhhlp_001335	MCM7	A0A2N3NHV1	A0A2N3N1K1	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
jhhlp_001335	jhhlp_003351	A0A2N3NHV1	A0A2N3NGJ5	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
jhhlp_001335	jhhlp_006101	A0A2N3NHV1	A0A2N3N4Z3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
jhhlp_001335	jhhlp_006622	A0A2N3NHV1	A0A2N3N6D5	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
jhhlp_001335	jhhlp_007697	A0A2N3NHV1	A0A2N3N0A8	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
jhhlp_003351	MCM7	A0A2N3NGJ5	A0A2N3N1K1	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
jhhlp_003351	jhhlp_001335	A0A2N3NGJ5	A0A2N3NHV1	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
jhhlp_003351	jhhlp_006101	A0A2N3NGJ5	A0A2N3N4Z3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
jhhlp_003351	jhhlp_006622	A0A2N3NGJ5	A0A2N3N6D5	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
jhhlp_003351	jhhlp_007697	A0A2N3NGJ5	A0A2N3N0A8	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
jhhlp_006101	MCM7	A0A2N3N4Z3	A0A2N3N1K1	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
jhhlp_006101	jhhlp_001335	A0A2N3N4Z3	A0A2N3NHV1	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
jhhlp_006101	jhhlp_003351	A0A2N3N4Z3	A0A2N3NGJ5	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
jhhlp_006101	jhhlp_006622	A0A2N3N4Z3	A0A2N3N6D5	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
jhhlp_006101	jhhlp_007697	A0A2N3N4Z3	A0A2N3N0A8	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999