(30 nodes) Toll Like Receptor 7/8 (TLR7/8) Cascade network (Puccinia graminis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PGTG_05215	Uncharacterized protein. (161 aa)
	PGTG_22636	STE/STE7 protein kinase. (597 aa)
	PGTG_22530	BZIP domain-containing protein. (993 aa)
	PGTG_20910	Mitogen-activated protein kinase kinase. (111 aa)
	PGTG_20747	STE protein kinase. (559 aa)
	PGTG_17888	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (271 aa)
	PGTG_17533	CIA30 domain-containing protein. (241 aa)
	PGTG_17183	Metallophos domain-containing protein. (415 aa)
	PGTG_13814	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (416 aa)
	PGTG_16812	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (493 aa)
	PGTG_06721	Uncharacterized protein. (1949 aa)
	PGTG_06617	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (412 aa)
	PGTG_07166	Uncharacterized protein. (399 aa)
	PGTG_07885	Protein phosphatase 2 (Formerly 2A), regulatory subunit A. (682 aa)
	PGTG_08310	Ubiquitin-40S ribosomal protein S27a-2. (159 aa)
	PGTG_08882	Serine/threonine-protein phosphatase. (305 aa)
	PGTG_10007	Uncharacterized protein. (570 aa)
	PGTG_10060	Uncharacterized protein. (80 aa)
	PGTG_11486	Uncharacterized protein. (493 aa)
	PGTG_11141	STE/STE7/MEK1 protein kinase; Belongs to the protein kinase superfamily. (454 aa)
	PGTG_13068	Polyubiquitin-A. (609 aa)
	PGTG_00549	RING-type domain-containing protein. (499 aa)
	PGTG_00763	BZIP domain-containing protein. (420 aa)
	PGTG_00812	Uncharacterized protein. (501 aa)
	PGTG_02790	Uncharacterized protein. (608 aa)
	PGTG_02309	Uncharacterized protein. (506 aa)
	PGTG_03141	Uncharacterized protein. (371 aa)
	PGTG_03567	Uncharacterized protein. (886 aa)
	PGTG_04715	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
	PGTG_05107	Mitogen-activated protein kinase kinase. (128 aa)

Your Current Organism:

Puccinia graminis

NCBI taxonomy Id: 418459
Other names: P. graminis f. sp. tritici CRL 75-36-700-3, Puccinia graminis f. sp. tritici CRL 75-36-700-3

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PGTG_00549	PGTG_08310	E3JRC9	E3KDZ2	RING-type domain-containing protein.	Ubiquitin-40S ribosomal protein S27a-2.	0.950
PGTG_00549	PGTG_13068	E3JRC9	E3KQW1	RING-type domain-containing protein.	Polyubiquitin-A.	0.978
PGTG_00549	PGTG_17533	E3JRC9	E3L552	RING-type domain-containing protein.	CIA30 domain-containing protein.	0.950
PGTG_00763	PGTG_00812	E3JTN9	E3JTX2	BZIP domain-containing protein.	Uncharacterized protein.	0.650
PGTG_00763	PGTG_04715	E3JTN9	E3K3V7	BZIP domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.679
PGTG_00763	PGTG_06617	E3JTN9	E3K8X9	BZIP domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.679
PGTG_00763	PGTG_10007	E3JTN9	E3KF07	BZIP domain-containing protein.	Uncharacterized protein.	0.679
PGTG_00763	PGTG_10060	E3JTN9	E3KJ65	BZIP domain-containing protein.	Uncharacterized protein.	0.650
PGTG_00763	PGTG_13814	E3JTN9	E3KUR0	BZIP domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.679
PGTG_00763	PGTG_16812	E3JTN9	E3L2N5	BZIP domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.679
PGTG_00763	PGTG_17888	E3JTN9	E3L6I3	BZIP domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.679
PGTG_00812	PGTG_00763	E3JTX2	E3JTN9	Uncharacterized protein.	BZIP domain-containing protein.	0.650
PGTG_00812	PGTG_02790	E3JTX2	E3JWC4	Uncharacterized protein.	Uncharacterized protein.	0.406
PGTG_00812	PGTG_03567	E3JTX2	E3JZY6	Uncharacterized protein.	Uncharacterized protein.	0.406
PGTG_00812	PGTG_11486	E3JTX2	E3KLW8	Uncharacterized protein.	Uncharacterized protein.	0.406
PGTG_00812	PGTG_22530	E3JTX2	H6QUS9	Uncharacterized protein.	BZIP domain-containing protein.	0.650
PGTG_02309	PGTG_08310	E3JXS3	E3KDZ2	Uncharacterized protein.	Ubiquitin-40S ribosomal protein S27a-2.	0.584
PGTG_02309	PGTG_13068	E3JXS3	E3KQW1	Uncharacterized protein.	Polyubiquitin-A.	0.514
PGTG_02309	PGTG_17533	E3JXS3	E3L552	Uncharacterized protein.	CIA30 domain-containing protein.	0.584
PGTG_02790	PGTG_00812	E3JWC4	E3JTX2	Uncharacterized protein.	Uncharacterized protein.	0.406