STRINGSTRING
PGTG_17926 PGTG_17926 PGTG_07890 PGTG_07890 PGTG_03766 PGTG_03766 PGTG_03746 PGTG_03746 PGTG_02111 PGTG_02111 PGTG_00608 PGTG_00608 PGTG_21346 PGTG_21346 PGTG_15286 PGTG_15286 PGTG_11250 PGTG_11250 UBA4 UBA4 UBA4-2 UBA4-2 PGTG_21081 PGTG_21081
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGTG_17926Ubiquitin-activating enzyme E1 C. (493 aa)
PGTG_07890Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (731 aa)
PGTG_03766NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. (588 aa)
PGTG_03746NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. (590 aa)
PGTG_02111ThiF domain-containing protein. (654 aa)
PGTG_00608Ubiquitin-activating enzyme E1 C. (673 aa)
PGTG_21346ThiF domain-containing protein. (141 aa)
PGTG_15286ThiF domain-containing protein. (384 aa)
PGTG_11250RING-type domain-containing protein. (819 aa)
UBA4Adenylyltransferase and sulfurtransferase UBA4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subseque [...] (508 aa)
UBA4-2Adenylyltransferase and sulfurtransferase UBA4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subseque [...] (509 aa)
PGTG_21081ThiF domain-containing protein. (96 aa)
Your Current Organism:
Puccinia graminis
NCBI taxonomy Id: 418459
Other names: P. graminis f. sp. tritici CRL 75-36-700-3, Puccinia graminis f. sp. tritici CRL 75-36-700-3
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